1996 US Open – Women's singles

Defending champion Steffi Graf defeated Monica Seles in a rematch of the previous year's final, 7–5, 6–4 to win the women's singles tennis title at the 1996 US Open. It was her fifth US Open title and 21st major singles title overall. Graf did not lose a set during the tournament.

This marked the final major appearance of 1990 champion Gabriela Sabatini. It was also the final major singles appearance of 15-time major quarterfinalist and former world No. 4 Zina Garrison.