Cholic acidCholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid that is insoluble in water (soluble in alcohol and acetic acid), it is a white crystalline substance. Salts of cholic acid are called cholates. Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids produced by the liver, where it is synthesized from cholesterol. These two major bile acids are roughly equal in concentration in humans.
Bile acidBile acids are steroidacids found predominantly in the bile of mammals and other vertebrates. Diverse bile acids are synthesized in the liver in peroxisomes. Bile acids are conjugated with taurine or glycine residues to give anions called bile salts. Primary bile acids are those synthesized by the liver. Secondary bile acids result from bacterial actions in the colon.
TaurineTaurine ( ; IUPAC: 2-aminoethanesulfonic acid) is a naturally occurring organic compound with the chemical formula H2N−CH2−CH2−SO2−OH in its non-zwitterionic form and H3N+−CH2−CH2−SO−3 in its zwitterionic form, and is a non-proteinogenic amino sulfonic acid widely distributed in mammalian tissues and organs.
HydrolysisHydrolysis (; from Ancient Greek hydro-'water' and lysis'to unbind') is any chemical reaction in which a molecule of water breaks one or more chemical bonds. The term is used broadly for substitution and elimination reactions in which water is the nucleophile. Biological hydrolysis is the cleavage of biomolecules where a water molecule is consumed to effect the separation of a larger molecule into component parts.
CholagogueA cholagogue is a substance that is purported by humoral practitioners to encourage the discharge of bile from the system, purging it downward. Deployment is no longer recommended because the biliary purge, like the traditional kidney purge, can cause pancreatic problems. In Patrick O'Brian's Post Captain (Ch.
BileBile (from Latin bilis), also known as gall, is a yellow-green fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine. In humans, bile is primarily composed of water, is produced continuously by the liver, and is stored and concentrated in the gallbladder. After a human eats, this stored bile is discharged into the first section of the small intestine, known as the duodenum through the ampulla of Vater in the duodenal wall.
MammalClass of animals with milk-producing glandsA mammal (from Latin mamma 'breast') is a vertebrate animal of the classMammalia (). Mammals are characterized by the presence of milk-producing mammary glands for feeding their young, a broad neocortex region of the brain, fur or hair, and three middle ear bones. These characteristics distinguish them from reptiles and birds, from which their ancestors diverged in the Carboniferous period over 300 million years ago.CholereticCholeretics are substances that increase the volume of secretion of bile from the liver as well as the amount of solids secreted.
CattleLarge, domesticated, cloven-hooved herbivoresCattle (Bos taurus) are large, domesticated, bovidungulates widely kept as livestock. They are prominent modern members of the subfamily Bovinae and the most widespread species of the genus Bos. Taurine cattle are widely distributed across Europe and temperate areas of Asia, the Americas, and Australia. Zebus are found mainly in India and tropical areas of Asia, America, and Australia.
Salt (chemistry)In chemistry, a salt or ionic compound is a chemical compound consisting of an assembly of positively charged ions (cations) and negatively charged ions (anions), which results in a compound with no net electric charge. The constituent ions are held together by electrostatic forces termed ionic bonds. The component ions in a salt can be either inorganic, such as chloride (Cl), or organic, such as acetate (CH3COO).
FatIn nutrition, biology, and chemistry, fat usually means any ester of fatty acids, or a mixture of such compounds, most commonly those that occur in living beings or in food. The term often refers specifically to triglycerides (triple esters of glycerol), that are the main components of vegetable oils and of fatty tissue in animals; or, even more narrowly, to triglycerides that are solid or semisolid at room temperature, thus excluding oils.
BiotransformationBiotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds. Biotransformations can be conducted with whole cells, their lysates, or purified enzymes. Increasingly, biotransformations are effected with purified enzymes. Major industries and life-saving technologies depend on biotransformations.*As an Amazon Associate I earn from qualifying purchases.