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Spray drying

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Spray drying is a method of forming a dry powder from a liquid or slurry by rapidly drying with a hot gas. This is the preferred method of drying of many thermally-sensitive materials such as foods and pharmaceuticals, or materials which may require extremely consistent, fine particle size. Air is most commonly used as the heated drying medium; however, nitrogen may be used if the liquid is flammable (such as ethanol) or if the product is oxygen-sensitive.

Spray nozzleSpray nozzleA spray nozzle or atomizer is a device that facilitates the dispersion of a liquid by the formation of a spray. The production of a spray requires the fragmentation of liquid structures, such as liquid sheets or ligaments, into droplets, often by using kinetic energy to overcome the cost of creating additional surface area.Amorphous solidAmorphous solidIn condensed matter physics and materials science, an amorphous solid (from Ancient Greek (a)'without' and (morphḗ)'shape, form'), or non-crystalline solid, is a solid that lacks the long-range order that is a characteristic of a crystal. The terms "glass" and "glassy solid" are sometimes used synonymously with amorphous solid; however, these terms refer specifically to amorphous materials that undergo a glass transition.Micro-encapsulationMicro-encapsulationMicroencapsulation is a process in which tiny particles or droplets are surrounded by a coating to give small capsules, with useful properties. In general, it is used to incorporate food ingredients, enzymes, cells or other materials on a micrometric scale. Microencapsulation can also be used to enclose solids, liquids, or gases inside a micrometric wall made of hard or soft soluble film, in order to reduce dosing frequency and prevent the degradation of pharmaceuticals.Ultrasonic nozzleUltrasonic nozzleUltrasonic nozzles are a type of spray nozzle that use high frequency vibrations produced by piezoelectric transducers acting upon the nozzle tip that create capillary waves in a liquid film. Once the amplitude of the capillary waves reaches a critical height (due to the power level supplied by the generator), they become too tall to support themselves and tiny droplets fall off the tip of each wave resulting in atomization.World War IIWorld War IIGlobal conflict from 1939 to 1945BelligerentsAlliesAxisCommanders and leadersMain Allied leaders: Joseph StalinFranklin D. RooseveltWinston ChurchillChiang Kai-shekMain Axis leaders: Adolf HitlerHirohitoBenito MussoliniCasualties and losses 60–75 million deaths (military and civilian) World War II, or the Second World War (1 September 1939 – 2 September 1945), was a global conflict between two coalitions: the Allies and the Axis powers.AmphiphileAmphiphileIn chemistry, an amphiphile (from Greekαμφις (amphis)'both' and φιλíα (philia)'love, friendship'), also referred to as an amphipath, is a dipolar chemical compound possessing both hydrophilic (water-loving, polar) and lipophilic (fat-loving, nonpolar) properties within the same molecule. Such compound is called amphiphilic or amphipathic.Modified starchModified starchModified starch, also called starch derivatives, is prepared by physically, enzymatically, or chemically treating native starch to change its properties. Modified starches are used in practically all starch applications, such as in food products as a thickening agent, stabilizer or emulsifier; in pharmaceuticals as a disintegrant; or as binder in coated paper. They are also used in many other applications.Fluidized bedFluidized bedA fluidized bed is a physical phenomenon that occurs when a solid particulate substance (usually present in a holding vessel) is under the right conditions so that it behaves like a fluid. The usual way to achieve a fluidized bed is to pump pressurized fluid into the particles. The resulting medium then has many properties and characteristics of normal fluids, such as the ability to free-flow under gravity, or to be pumped using fluid technologies.EthanolEthanolOrganic compoundA bottle of ethanolNames Pronunciation Preferred IUPAC nameEthanolOther names Absolute alcoholAlcoholCologne spiritDrinking alcoholEthylic alcoholEthyl alcoholEthyl hydroxideEthylene hydrateEthylolGrain alcoholHydroxyethaneMethylcarbinolIdentifiers CAS Number64-17-53D model (JSmol)Interactive imageAbbreviations EtOH Beilstein Reference1718733 ChEBICHEBI:16236ChEMBLChEMBL545ChemSpider682DrugBankDB00898ECHA InfoCard100.000.526Gmelin Reference787 IUPHAR/BPS2299KEGGC00469PubChemCID702UNII3K9958V90MUN numberUN 1170 CompTox Dashboard(EPA)DTXSID9020584InChIInChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3Key: LFQSCWFLJHTTHZ-UHFFFAOYSA-NInChI=1/C2H6O/c1-2-3/h3H,2H2,1H3Key: LFQSCWFLJHTTHZ-UHFFFAOYABSMILESOCCProperties Chemical formulaC2H6OMolar mass46.069 g·mol Appearance Colorless liquid Odorwine-like, pungent Density0.78945 g/cm (at 20 °C) Melting point−114.14 ± 0.03 °C (−173.45 ± 0.05 °F; 159.01 ± 0.03 K) Boiling point78.23 ± 0.09 °C (172.81 ± 0.16 °F; 351.38 ± 0.09 K) Solubility in waterMisciblelog P−0.31 Vapor pressure5.95 kPa (at 20 °C) Acidity (pKa) 15.9 (H2O), 29.8 (DMSO) Magnetic susceptibility (χ)−33.60·10 cm/mol Refractive index (nD)1.3611 Viscosity1.2 mPa·s (at 20 °C), 1.074 mPa·s (at 25 °C) Dipole moment1.69 D Hazards GHS labelling: PictogramsSignal wordDangerHazard statementsH225, H319, H360DPrecautionary statementsP210, P233, P240, P241, P242, P305+P351+P338NFPA 704 (fire diamond) 230Flash point14 °C (57 °F; 287 K) (Absolute) Lethal dose or concentration (LD, LC): LD50 (median dose)7060 mg/kg (oral, rat)3450 mg/kg (mouse)NIOSH (US health exposure limits): PEL (Permissible)TWA 1000 ppm (1900 mg/m) REL (Recommended)TWA 1000 ppm (1900 mg/m) IDLH (Immediate danger)3300 ppm Safety data sheet (SDS) Related compounds Related compoundsEthaneMethanolSupplementary data page Ethanol (data page)Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).N verify ( ?)NitrogenNitrogenChemical element with atomic number 7 (N)–↑N↓Pcarbon ← nitrogen → oxygenMedicationMedicationMedication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in many ways.

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