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Ringer's lactate solution

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Ringer's lactate solution (RL), also known as sodium lactate solution or Lactated Ringer's (LR), is a mixture of sodium chloride, sodium lactate, potassium chloride, and calcium chloride in water. It is used for replacing fluids and electrolytes in those who have low blood volume or low blood pressure. It may also be used to treat metabolic acidosis and to wash the eye following a chemical burn. It is given by intravenous infusion or applied to the affected area.

Sodium lactateSodium lactateNames Preferred IUPAC nameSodium 2-hydroxypropanoateOther names Sodium DL-lactateLactic acid sodium saltE325Identifiers CAS Number72-17-33D model (JSmol)Interactive imageChEBICHEBI:75228ChEMBLChEMBL1357ChemSpider6049ECHA InfoCard100.000.702E numberE325 (antioxidants, ...)PubChemCID6286UNIITU7HW0W0QTCompTox Dashboard(EPA)DTXSID6052829InChIInChI=1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1Key: NGSFWBMYFKHRBD-UHFFFAOYSA-MInChI=1/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1Key: NGSFWBMYFKHRBD-REWHXWOFARSMILES[Na+].[O-]C(=O)C(O)CProperties Chemical formulaC3H5NaO3Molar mass112.06 g/mol Appearance White powder Density1.33 g/mL, 1.31 g/ml (60 % syrup) Melting point161 to 162 °C (322 to 324 °F; 434 to 435 K) 17 °C (60 % syrup) Boiling point113 °C (235 °F; 386 K) (60 % syrup) Solubility in water> 1.5 g/mL Hazards Flash point< 25 Lethal dose or concentration (LD, LC): LD50 (median dose)1000 mg/kg (intravenous, rat) Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).Nverify ( ?)Potassium chloridePotassium chloridePotassium chloride (KCl, or potassium salt) is a metal halidesalt composed of potassium and chlorine. It is odorless and has a white or colorlessvitreouscrystal appearance. The solid dissolves readily in water, and its solutions have a salt-like taste. Potassium chloride can be obtained from ancient dried lake deposits.Calcium chlorideCalcium chlorideChemical compoundChemical compoundCalcium chloride is an inorganic compound, a salt with the chemical formulaCaCl2. The compound is a white crystalline solid at room temperature, and it is highly soluble in water. The salt can be created by neutralising hydrochloric acid with calcium hydroxide. Calcium chloride is commonly encountered as a hydrated solid with generic formula CaCl2·nH2O, where n = 0, 1, 2, 4, and 6.Metabolic acidosisMetabolic acidosisMetabolic acidosis is a serious electrolyte disorder characterized by an imbalance in the body's acid-base balance. Metabolic acidosis has three main root causes: increased acid production, loss of bicarbonate, and a reduced ability of the kidneys to excrete excess acids. Metabolic acidosis can lead to acidemia, which is defined as arterial blood pH that is lower than 7.35.Sodium chlorideSodium chlorideSodium chloride , is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. It is transparent or translucent, brittle, hygroscopic, and occurs as the mineral halite. In its edible form, common table salt, it is commonly used as a condiment and food preservative.HypervolemiaHypervolemiaHypervolemia, also known as fluid overload, is the medical condition where there is too much fluid in the blood. The opposite condition is hypovolemia, which is too little fluid volume in the blood. Fluid volume excess in the intravascular compartment occurs due to an increase in total body sodium content and a consequent increase in extracellular body water.HypovolemiaHypovolemiaHypovolemia, also known as volume depletion or volume contraction, is a state of abnormally low extracellular fluid in the body. This may be due to either a loss of both salt and water or a decrease in blood volume. Hypovolemia refers to the loss of extracellular fluid and should not be confused with dehydration. Hypovolemia is caused by a variety of events, but these can be simplified into two categories: those that are associated with kidney function and those that are not.WaterWaterNames Preferred IUPAC nameWaterSystematic IUPAC nameOxidane (not in common use)Other names Hydrogen oxideHydrogen hydroxide (H2O or HOH)Hydroxylic acidDihydrogen monoxide (DHMO) (parody name)Dihydrogen oxideHydric acidHydrohydroxic acidHydroxic acidHydroxoic acidHydrolμ-Oxidodihydrogenκ-Hydroxylhydrogen(0)AquaNeutral liquidOxygen dihydride (may be considered incorrect)Identifiers CAS Number7732-18-53D model (JSmol)Interactive imageBeilstein Reference3587155 ChEBICHEBI:15377ChEMBLChEMBL1098659ChemSpider937DrugBankDB09145ECHA InfoCard100.028.902EC Number231-791-2Gmelin Reference117 KEGGC00001PubChemCID962RTECS numberZC0110000UNII059QF0KO0RCompTox Dashboard(EPA)DTXSID6026296InChIInChI=1S/H2O/h1H2Key: XLYOFNOQVPJJNP-UHFFFAOYSA-NSMILESOProperties Chemical formulaH2OMolar mass18.015 g·mol Appearance Almost colorless or white crystalline solid, almost colorless liquid, with a hint of blue, colorless gas OdorOdorless DensityLiquid (1 atm, VSMOW):0.99984283(84) g/mL at 0 °C0.99997495(84) g/mL at 3.983035(670) °C (temperature of maximum density, often 4 °C)0.99704702(83) g/mL at 25 °C0.96188791(96) g/mL at 95 °CSolid:0.9167 g/mL at 0 °CMelting point0.00 °C (32.00 °F; 273.15 K) Boiling point99.98 °C (211.96 °F; 373.13 K) SolubilityPoorly soluble in haloalkanes, aliphatic and aromatic hydrocarbons, ethers.Chemical burnChemical burnA chemical burn occurs when living tissue is exposed to a corrosive substance (such as a strong acid, base or oxidizer) or a cytotoxic agent (such as mustard gas, lewisite or arsine). Chemical burns follow standard burn classification and may cause extensive tissue damage. The main types of irritant and/or corrosive products are: acids, bases, oxidizers and reducing agents, solvents, and alkylants.HyperkalemiaHyperkalemiaHyperkalemia is an elevated level of potassium (K) in the blood. Normal potassium levels are between 3.5 and 5.0mmol/L (3.5 and 5.0mEq/L) with levels above 5.5mmol/L defined as hyperkalemia. Typically hyperkalemia does not cause symptoms. Occasionally when severe it can cause palpitations, muscle pain, muscle weakness, or numbness. Hyperkalemia can cause an abnormal heart rhythm which can result in cardiac arrest and death.ElectrolyteElectrolyteAn electrolyte is a substance that conducts electricity through the movement of ions, but not through the movement of electrons. This includes most soluble salts, acids, and bases, dissolved in a polar solvent like water. Upon dissolving, the substance separates into cations and anions, which disperse uniformly throughout the solvent. Solid-state electrolytes also exist. In medicine and sometimes in chemistry, the term electrolyte refers to the substance that is dissolved.Intravenous therapyIntravenous therapyIntravenous therapy (abbreviated as IV therapy) is a medical process that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.HypotensionHypotensionHypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure. Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood and is indicated by two numbers, the systolic blood pressure (the top number) and the diastolic blood pressure (the bottom number), which are the maximum and minimum blood pressures within the cardiac cycle, respectively.

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