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Rectal administration

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Rectal administration uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels, and flow into the body's circulatory system, which distributes the drug to the body's organs and bodily systems. UsesMedical usesIn addition to pharmacological effects, rectal administration has some properties which can be advantageous for the use in medicine. Rectal administration can allow patients to remain in the home setting when the oral route is compromised.

Intravenous therapyIntravenous therapyIntravenous therapy (abbreviated as IV therapy) is a medical process that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.Macy CatheterThe Macy Catheter is a specialized catheter designed to provide comfortable and discreet administration of ongoing medications via the rectal route. The catheter was developed to make rectal access more practical and provide a way to deliver and retain liquid formulations in the distal rectum so that health practitioners can leverage the established benefits of rectal administration.Route of administrationRoute of administrationIn pharmacology and toxicology, a route of administration (ROA) is the way by which a drug, fluid, poison, or other substance is introduced into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration. Routes can also be classified based on where the target of action is.EnemaEnemaFluid injection into the large intestineRectal bulb syringe to administer smaller enemasAn enema, also known as a clyster, is the rectal administration of a fluid by injection into the lower bowel via the anus. The word enema can also refer to the liquid injected, as well as to a device for administering such an injection.MedicationMedicationMedication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in many ways.Circulatory systemCirculatory systemOrgan system for circulating blood in animalsIn vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek kardia meaning heart, and Latin vascula meaning vessels).HospiceHospiceHospice care is a type of health care that focuses on the palliation (providing relief of pain) of a terminally ill patient's pain and symptoms and attending to their emotional and spiritual needs at the end of life. Hospice care prioritizes comfort and quality of life by reducing pain and suffering.Blood vesselBlood vesselBlood vessels are the tubular structures of a circulatory system transporting blood in animal bodies. Blood vessels transport blood cells, nutrients, and oxygen to most of the tissues of a body, and also transport waste products and carbon dioxide away from the tissues. Some tissues – such as cartilage, epithelium, and the lens and cornea of the eye – are not supplied with blood vessels, so are termed avascular.RectumRectumThe rectum (pl.: rectums or recta) is the final straight portion of the large intestine in humans and some other mammals, and the gut in others. Before expulsion through the anus or cloaca, the rectum stores the feces temporarily. The adult human rectum is about 12 centimetres (4.7 in) long, and begins at the rectosigmoid junction (the end of the sigmoid colon) at the level of the third sacral vertebra or the sacral promontory depending upon what definition is used.Biological systemBiological systemA biological system is a complex network which connects several biologically relevant entities. Biological organization spans several scales and is determined based on different structures depending on what the system is. Examples of biological systems at the macro scale are populations of organisms. On the organ and tissue scale in mammals and other animals, examples include the circulatory system, the respiratory system, and the nervous system.Absorption (pharmacology)Absorption is the journey of a drug travelling from the site of administration to the site of action. The drug travels by some route of administration (oral, topical-dermal, etc.) in a chosen dosage form (e.g., tablets, capsules, or in solution). Absorption by some other routes, such as intravenous therapy, intramuscular injection, enteral nutrition, is even more straightforward and there is less variability in absorption and bioavailability is often near 100%.Organ (biology)Organ (biology)In a multicellular organism, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The intestinal wall, for example, is formed by epithelial tissue and smooth muscle tissue.

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