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RNA world

Hypothetical stage in the early evolutionary history of life on EarthA comparison of RNA (left) with DNA (right), showing the helices and nucleobases each employsThe RNA world is a hypothetical stage in the evolutionary history of life on Earth in which self-replicatingRNA molecules proliferated before the evolution of DNA and proteins. The term also refers to the hypothesis that posits the existence of this stage.

AbiogenesisAbiogenesisLife arising from non-living matterStages in the origin of life process range from the well understood, such as the habitable Earth and the abiotic synthesis of simple molecules, to the largely unknown, like the derivation of the last universal common ancestor (LUCA) with its complex molecular functionalities.Abiogenesis or the origin of life (sometimes called biopoiesis) is the natural process by which life arises from non-living matter, such as simple organic compounds.RNP worldRNP worldThe RNP world is a hypothesized intermediate period in the origin of life characterized by the primary metabolic role of ribonucleoproteins. The period followed the hypothesized RNA world and ended with the formation of DNA and contemporary proteins. In the RNP world, RNA molecules began to synthesize peptides. These would eventually become proteins which have since assumed most of the diverse functions RNA performed previously.DNADNAMolecule that carries genetic informationThe structure of the DNA double helix (type B-DNA). The atoms in the structure are colour-coded by element and the detailed structures of two base pairs are shown in the bottom right.Simplified diagramDeoxyribonucleic acid (pronunciation; DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.ProteinProteinBiomolecule consisting of chains of amino acid residuesA representation of the 3D structure of the protein myoglobin showing turquoise α-helices. This protein was the first to have its structure solved by X-ray crystallography. Toward the right-center among the coils, a prosthetic group called a heme group (shown in gray) with a bound oxygen molecule (red).Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acidresidues.LifeLifeLife is the capacity in matter, formed of one or more units called cells, for processes such as cell signaling, homeostasis, metabolism, cell growth, adaptation, response to stimuli, and reproduction. All life eventually reaches a state of death. Many philosophical definitions of living systems have been proposed, such as self-organizing systems.Self-replicationSelf-replicationSelf-replication is any behavior of a dynamical system that yields construction of an identical or similar copy of itself. Biological cells, given suitable environments, reproduce by cell division. During cell division, DNA is replicated and can be transmitted to offspring during reproduction. Biological viruses can replicate, but only by commandeering the reproductive machinery of cells through a process of infection.RNARNAFamily of large biological moleculesA hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). This is a single strand of RNA that folds back upon itself. Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA).Alexander RichAlexander RichAlexander Rich (15 November 1924 – 27 April 2015) was an American biologist and biophysicist. He was the William Thompson Sedgwick Professor of Biophysics at the Massachusetts Institute of Technology (since 1958) and Harvard Medical School. Rich earned an A.B. (magna cum laude) and an M.D. (cum laude) from Harvard University. He was a post-doc of Linus Pauling.FalsifiabilityFalsifiabilityFalsifiability is a standard of evaluation of scientific statements, including theories and hypotheses. A statement is falsifiable if it belongs to a language or logical structure capable of describing an empirical observation that contradicts it. In the case of a theory, falsifiability requires that, given an initial condition, the theory must theoretically exclude some observations, that is, it must make formal predictions.Walter GilbertWalter GilbertWalter Gilbert (born March 21, 1932) is an American biochemist, physicist, molecular biology pioneer, and Nobel laureate.History of lifeHistory of lifeThe history of life on Earth traces the processes by which living and extinct organisms evolved, from the earliest emergence of life to the present day. Earth formed about 4.54 ± 0.05 billion years ago (abbreviated as Ga, for gigaannum) and evidence suggests that life emerged prior to 3.7 Ga. The similarities among all known present-day species indicate that they have diverged through the process of evolution from a common ancestor.Data storageData storageData storage is the recording (storing) of information (data) in a storage medium. Handwriting, phonographic recording, magnetic tape, and optical discs are all examples of storage media. Biological molecules such as RNA and DNA are considered by some as data storage. Recording may be accomplished with virtually any form of energy. Electronic data storage requires electrical power to store and retrieve data.

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