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Permissive cell

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A permissive cell or permissive host is one that allows a virus to circumvent its defenses and replicate. Usually this occurs when the virus has modulated one or several of the host cellular intrinsic defenses and the host immune system. The permissive state of a host has now been determined to be the primary factor in determining whether a virus will cause pathological symptoms in a host. Susceptible versus permissiveA virus can enter a susceptible cell, but it may or may not be able to replicate.

Myxoma virusMyxoma virusMyxoma virus is a poxvirus in the genus Leporipoxvirus. The two broad geographic types of Myxoma virus are Californian and South American. Californian myxoma virus is found on the West Coast of the United States, the Baja Peninsula of Mexico, and the southwest coast of Canada. South American or Brazilian myxoma virus is found in South and Central America.Susceptible individualSusceptible individualIn epidemiology a susceptible individual (sometimes known simply as a susceptible) is a member of a population who is at risk of becoming infected by a disease. Susceptible individualsSusceptibles have been exposed to neither the wild strain of the disease nor a vaccination against it, and thus have not developed immunity.InterferonInterferonInterferons (IFNs, IN-tər-FEER-on) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses. IFNs belong to the large class of proteins known as cytokines, molecules used for communication between cells to trigger the protective defenses of the immune system that help eradicate pathogens.RabbitRabbitMammals of the family LeporidaeRabbits, or bunnies, are small mammals in the familyLeporidae (which also includes the hares), which is in the orderLagomorpha (which also includes pikas). They are familiar throughout the world as a small herbivore, a prey animal, a domesticated form of livestock, and a pet, having a widespread effect on ecologies and cultures. The most widespread rabbit genera are Oryctolagus and Sylvilagus.Viral sheddingViral sheddingViral shedding is the expulsion and release of virus progeny following successful reproduction during a hostcell infection. Once replication has been completed and the host cell is exhausted of all resources in making viral progeny, the viruses may begin to leave the cell by several methods.InoculationInoculationInoculation is the act of implanting a pathogen or other microbe or virus into a person or other organism. It is a method of artificially inducing immunity against various infectious diseases. The term "inoculation" is also used more generally to refer to intentionally depositing microbes into any growth medium, as into a Petri dish used to culture the microbe, or into food ingredients for making cultured foods such as yoghurt and fermented beverages such as beer and wine.Immune systemImmune systemBiological system protecting an organism against diseaseThe immune system is a network of biological systems that protects an organism from diseases. It detects and responds to a wide variety of pathogens, such as viruses, bacteria, and parasites, as well as cancer cells and foreign objects, such as wood splinters—distinguishing them from the organism's own healthy tissue. Many species have two major subsystems of the immune system.VirusVirusInfectious agent that replicates in cellsA virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity.ImmunosuppressionImmunosuppressionImmunosuppression is a reduction of the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions. In general, deliberately induced immunosuppression is performed to prevent the body from rejecting an organ transplant.

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