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Organomercury chemistry

Organomercury chemistry refers to the study of organometallic compounds that contain mercury. Many organomercury compounds are highly toxic, but some are, or have once been, used in medicine, e.g., merbromin ("Mercurochrome") and the vaccine preservative thiomersal. Structure and bondingMost organomercury compounds feature diamagnetic Hg(II) and adopt a linear C−Hg−X structure. Indeed, no organic derivatives of Hg2 are known, as Hg2 requires electronegative substituents for condensed-phase stability.

Grignard reagentGrignard reagentGrignard reagents or Grignard compounds are chemical compounds with the general formula RMgX(S)n, where X is a halide, R is an organic group (normally an alkyl or aryl), S is an ether, and n is usually 2. Usually, the ether groups are omitted from the formula. Thus, two typical examples are methylmagnesium chlorideClMgCH3 and phenylmagnesium bromideC6H5MgBr. They are a subclass of the organomagnesium compounds.MetalloceneMetalloceneA metallocene is a compound typically consisting of two cyclopentadienyl anions (C5H−5, abbreviated Cp) bound to a metal center (M). They have the general formula (C5R5)2M]+ (R = H, alkyl typically). Closely related to the metallocenes are the metallocene derivatives, e.g. titanocene dichloride or vanadocene dichloride. Certain metallocenes and their derivatives exhibit catalytic properties, although metallocenes are rarely used industrially.DiamagnetismDiamagnetismDiamagnetism is a form of magnetic response in materials that describes the property being repelled by an applied magnetic field; application of such creates in them an induced magnetic field in the opposite direction, thus causing a repulsive force. In contrast, paramagnetic and ferromagnetic materials are attracted by a magnetic field.Mercury (element)Mercury (element)Chemical element with atomic number 80 (Hg)Cd↑Hg↓Cngold ← mercury → thalliumDiphenylmercuryDiphenylmercuryDiphenylmercury is the organomercury compound with the formula Hg(C6H5)2. It is a white solid. The compound is of historic interest as a particularly stable organometallic compound but it finds few uses because of its high toxicity.ThiomersalThiomersalThiomersal (INN), or thimerosal (USAN, JAN), also sold under the name merthiolate, is an organomercury compound. It is a well-established antiseptic and antifungal agent. It has been used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks.Laboratory glasswareLaboratory glasswareLaboratory glassware is a variety of equipment used in scientific work, traditionally made of glass. Glass may be blown, bent, cut, molded, or formed into many sizes and shapes. It is commonly used in chemistry, biology, and analytical laboratories. Many laboratories have training programs to demonstrate how glassware is used and to alert first–time users to the safety hazards involved with using glassware.MerbrominMerbrominMerbromin (marketed as Mercurochrome, Merbromine, Mercurocol, Sodium mercurescein, Asceptichrome, Supercrome, Brocasept and Cinfacromin) is an organomercuricdisodiumsaltcompound used as a topicalantiseptic for minor cuts and scrapes and as a biological dye. While readily available in most countries, it is no longer sold in much of the West, including Switzerland, Brazil, France, Iran, Germany, Denmark, or the United States, due to its mercury content.Organometallic chemistryOrganometallic chemistryOrganometallic chemistry is the study of organometallic compounds, chemical compounds containing at least one chemical bond between a carbon atom of an organic molecule and a metal, including alkali, alkaline earth, and transition metals, and sometimes broadened to include metalloids like boron, silicon, and selenium, as well.Organocadmium chemistryOrganocadmium chemistryOrganocadmium chemistry describes the physical properties, synthesis, reactions, and use of organocadmium compounds, which are organometallic compounds containing a carbon to cadmium chemical bond. Cadmium shares group 12 with zinc and mercury and their corresponding chemistries have much in common. The synthetic utility of organocadmium compounds is limited. The simplest organocadmium compound is dimethylcadmium.Lewis acids and basesLewis acids and basesA Lewis acid is a chemical species that contains an empty orbital which is capable of accepting an electron pair from a Lewis base to form a Lewis adduct. A Lewis base, then, is any species that has a filled orbital containing an electron pair which is not involved in bonding but may form a dative bond with a Lewis acid to form a Lewis adduct. For example, NH3 is a Lewis base, because it can donate its lone pair of electrons.IodomethaneIodomethane, also called methyl iodide, and commonly abbreviated "MeI", is the chemical compound with the formula CH3I. It is a dense, colorless, volatile liquid. In terms of chemical structure, it is related to methane by replacement of one hydrogen atom by an atom of iodine. It is naturally emitted in small amounts by rice plantations.

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