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Nuclear magnetic resonance spectroscopy

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Nuclear magnetic resonance spectroscopy, commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique based on re-orientation of atomic nuclei with non-zero nuclear spins in an external magnetic field. This re-orientation occurs with absorption of electromagnetic radiation in the radio frequency region from roughly 4 to 900 MHz, which depends on the isotopic nature of the nucleus and increases proportionally to the strength of the external magnetic field.

Nuclear magnetic resonanceNuclear magnetic resonanceSpectroscopic technique based on change of nuclear spin stateBruker 700 MHz nuclear magnetic resonance (NMR) spectrometer.Nuclear Magnetic Resonance (NMR) basic principlesNuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are disturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus.Carbon-13 nuclear magnetic resonanceCarbon-13 nuclear magnetic resonanceCarbon-13 (C13) nuclear magnetic resonance (most commonly known as carbon-13 NMR spectroscopy or C NMR spectroscopy or sometimes simply referred to as carbon NMR) is the application of nuclear magnetic resonance (NMR) spectroscopy to carbon. It is analogous to proton NMR (H NMR) and allows the identification of carbon atoms in an organic molecule just as proton NMR identifies hydrogen atoms. C NMR detects only the Cisotope.Proton nuclear magnetic resonanceProton nuclear magnetic resonanceProton nuclear magnetic resonance (proton NMR, hydrogen-1 NMR, or 1H NMR) is the application of nuclear magnetic resonance in NMR spectroscopy with respect to hydrogen-1 nuclei within the molecules of a substance, in order to determine the structure of its molecules. In samples where natural hydrogen (H) is used, practically all the hydrogen consists of the isotope 1H (hydrogen-1; i.e. having a proton for a nucleus).SpectroscopySpectroscopyStudy involving matter and electromagnetic radiationA prism separates white light by dispersing it into its component colors, which can then be studied using spectroscopy.Spectroscopy is the field of study that measures and interprets electromagnetic spectra as it interacts with matter. In narrower contexts, spectroscopy is the precise study of color as generalized from radiated visible light to all bands of the electromagnetic spectrum.Functional groupFunctional groupIn organic chemistry, a functional group is any substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions. The same functional group will undergo the same or similar chemical reactions regardless of the rest of the molecule's composition. This enables systematic prediction of chemical reactions and behavior of chemical compounds and the design of chemical synthesis.Atomic nucleusAtomic nucleusThe atomic nucleus is the small, dense region consisting of protons and neutrons at the center of an atom, discovered in 1911 by Ernest Rutherford at the University of Manchester based on the 1909 Geiger–Marsden gold foil experiment. After the discovery of the neutron in 1932, models for a nucleus composed of protons and neutrons were quickly developed by Dmitri Ivanenko and Werner Heisenberg.IsotopeIsotopeIsotopes are distinct nuclear species (or nuclides) of the same chemical element. They have the same atomic number (number of protons in their nuclei) and position in the periodic table (and hence belong to the same chemical element), but different nucleon numbers (mass numbers) due to different numbers of neutrons in their nuclei. While all isotopes of a given element have virtually the same chemical properties, they have different atomic masses and physical properties.Radio frequencyRadio frequencyRadio frequency (RF) is the oscillation rate of an alternating electric current or voltage or of a magnetic, electric or electromagnetic field or mechanical system in the frequency range from around 20 kHz to around 300 GHz. These are the frequencies at which energy from an oscillating current can radiate off a conductor into space as radio waves, so they are used in radio technology, among other uses.Spin quantum numberIn chemistry and quantum mechanics, the spin quantum number is a quantum number (designated s) that describes the intrinsic angular momentum (or spin angular momentum, or simply spin) of an electron or other particle. It has the same value for all particles of the same type, such as s = ⁠1/2⁠ for all electrons. It is an integer for all bosons, such as photons, and a half-odd-integer for all fermions, such as electrons and protons.Spin (physics)Spin (physics)Spin is an intrinsic form of angular momentum carried by elementary particles, and thus by composite particles such as hadrons, atomic nuclei, and atoms. Spin is quantized, and accurate models for the interaction with spin require relativistic quantum mechanics or quantum field theory.ProteinProteinBiomolecule consisting of chains of amino acid residuesA representation of the 3D structure of the protein myoglobin showing turquoise α-helices. This protein was the first to have its structure solved by X-ray crystallography. Toward the right-center among the coils, a prosthetic group called a heme group (shown in gray) with a bound oxygen molecule (red).Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acidresidues.

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