Brain-derived neurotrophic factor
Tropomyosin receptor kinase CProtein found in humansMore reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 15: 87.86 – 88.26 MbChr 7: 78.18 – 78.74 MbPubMed searchWikidataTropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase, is a protein that in humans is encoded by the NTRK3gene.Growth factorNerve growth factor
NeurotrophinNeurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death – allowing the neurons to survive.
Neurotrophic factorsNeurotrophic factors (NTFs) are a family of biomolecules – nearly all of which are peptides or small proteins – that support the growth, survival, and differentiation of both developing and mature neurons. Most NTFs exert their trophic effects on neurons by signaling through tyrosine kinases, usually a receptor tyrosine kinase. In the mature nervous system, they promote neuronal survival, induce synaptic plasticity, and modulate the formation of long-term memories.
NeuronPrimary cell of the nervous systemA neuron (American English), neurone (British English), or nerve cell, is a cell that is excitable, firing electric signals called action potentials. Neurons form neural networks in the nervous system, mainly in the central nervous system. Neurons receive and conduct impulses.
ProteinBiomolecule consisting of chains of amino acid residuesA representation of the 3D structure of the protein myoglobin showing turquoise α-helices. This protein was the first to have its structure solved by X-ray crystallography. Toward the right-center among the coils, a prosthetic group called a heme group (shown in gray) with a bound oxygen molecule (red).Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acidresidues.
Central nervous systemThe central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and the spinal cord. The retina is also technically part of the CNS. The CNS is named so because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts.
Tropomyosin receptor kinase BProtein and coding gene in humansMore reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 9: 84.67 – 85.03 MbChr 13: 58.95 – 59.28 MbPubMed searchWikidataTropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2gene.
SynapseIn the nervous system, a synapse is a structure that allows a neuron to exchange (receive or send) signals with another cell in its immediate vicinity. Synapses can be classified as either chemical or electrical, depending on the mechanism of signal transmission between neurons. In the case of electrical synapses, neurons are coupled bidirectionally with each other through gap junctions and have a connected cytoplasmic milieu.
GeneSequence of DNA that determines traits in an organismIn biology, the word gene has two meanings. The Mendelian gene is a basic unit of . The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of RNA or protein from a gene), DNA is first copied into RNA.
Tropomyosin receptor kinase CProtein found in humansMore reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 15: 87.86 – 88.26 MbChr 7: 78.18 – 78.74 MbPubMed searchWikidataTropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase, is a protein that in humans is encoded by the NTRK3gene.Growth factorNerve growth factorNeurotrophinNeurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death – allowing the neurons to survive.Neurotrophic factorsNeurotrophic factors (NTFs) are a family of biomolecules – nearly all of which are peptides or small proteins – that support the growth, survival, and differentiation of both developing and mature neurons. Most NTFs exert their trophic effects on neurons by signaling through tyrosine kinases, usually a receptor tyrosine kinase. In the mature nervous system, they promote neuronal survival, induce synaptic plasticity, and modulate the formation of long-term memories.NeuronPrimary cell of the nervous systemA neuron (American English), neurone (British English), or nerve cell, is a cell that is excitable, firing electric signals called action potentials. Neurons form neural networks in the nervous system, mainly in the central nervous system. Neurons receive and conduct impulses.ProteinBiomolecule consisting of chains of amino acid residuesA representation of the 3D structure of the protein myoglobin showing turquoise α-helices. This protein was the first to have its structure solved by X-ray crystallography. Toward the right-center among the coils, a prosthetic group called a heme group (shown in gray) with a bound oxygen molecule (red).Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acidresidues.Central nervous systemThe central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and the spinal cord. The retina is also technically part of the CNS. The CNS is named so because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts.Tropomyosin receptor kinase BProtein and coding gene in humansMore reference expression dataBioGPSEnsemblUniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)Chr 9: 84.67 – 85.03 MbChr 13: 58.95 – 59.28 MbPubMed searchWikidataTropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2gene.SynapseIn the nervous system, a synapse is a structure that allows a neuron to exchange (receive or send) signals with another cell in its immediate vicinity. Synapses can be classified as either chemical or electrical, depending on the mechanism of signal transmission between neurons. In the case of electrical synapses, neurons are coupled bidirectionally with each other through gap junctions and have a connected cytoplasmic milieu.GeneSequence of DNA that determines traits in an organismIn biology, the word gene has two meanings. The Mendelian gene is a basic unit of . The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of RNA or protein from a gene), DNA is first copied into RNA.*As an Amazon Associate I earn from qualifying purchases.