Viral hemorrhagic feverViral hemorrhagic fevers (VHFs) are a diverse group of infectious diseases characterized by fever and systemic damage to the circulatory system caused by RNA viruses. Viral hemorrhagic fevers cause symptoms ranging from mild to life-threatening, depending on the virus involved, but generally cause internal bleeding that leads to sudden onset of muscle pain, fever, and hypotension. In severe cases, it can cause life-threatening shock and bleeding from internal organs.
Marburg virusMarburg virus (MARV) is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus. It causes Marburg virus disease in primates, a form of viral hemorrhagic fever. The World Health Organization (WHO) rates it as a Risk Group 4 Pathogen (requiring biosafety level 4-equivalent containment).
Egyptian fruit batThe Egyptian fruit bat or Egyptian rousette (Rousettus aegyptiacus) is a species of megabat that occurs in Africa, the Middle East, the Mediterranean and the Indian subcontinent. It is one of three species of Rousettus with an African-Malagasy range, though the only species of its genus found in continental Africa. The common ancestor of the three species colonised the region in the late Pliocene or early Pleistocene. The species is traditionally divided into six subspecies.
Ravn virusRavn virus (; RAVV) is a close relative of Marburg virus (MARV). RAVV causes Marburg virus disease, a form of viral hemorrhagic fever in humans and nonhuman primates.
Disseminated intravascular coagulationDisseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels. Symptoms may include chest pain, shortness of breath, leg pain, problems speaking, or problems moving parts of the body. As clotting factors and platelets are used up, bleeding may occur. This may include blood in the urine, blood in the stool, or bleeding into the skin. Complications may include organ failure.
MarburgvirusThe genusMarburgvirus is the taxonomic home of Marburg marburgvirus, whose members are the two known marburgviruses, Marburg virus (MARV) and Ravn virus (RAVV). Both viruses cause Marburg virus disease in humans and nonhuman primates, a form of viral hemorrhagic fever.
EbolaEbola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a zoonoticviral hemorrhagic fever in humans and other primates, caused by four of the six known ebolaviruses. Symptoms typically start anywhere between two days and three weeks after infection. The first symptoms are usually fever, sore throat, muscle pain, and headaches.
PrimateOrder of mammalsPrimates is an order of mammals, which is further divided into the strepsirrhines, which include lemurs, galagos, and lorisids; and the haplorhines, which include tarsiers and simians (monkeys and apes).
Equatorial AfricaEquatorial Africa is an ambiguous term that is sometimes used to refer to the equatorial region of sub-Saharan Africa traversed by the Equator, more broadly to tropical Africa, or in a biological and geo-environmental sense to the intra-tropical African rainforest region. See alsoCentral AfricaFrench Equatorial AfricaSaharaSahelSudan (region)TropicsReferencesExternal links"Equatorial Africa: Material Culture from Peoples of the Congo, Uganda & Kenya". Museum of Anthropology.
Signs and symptomsSigns and symptoms (S/S) are diagnostic indications of an illness, injury, or condition. While signs are objective and externally observable, symptoms are a person's reported subjective experiences. A sign, for example, can be an elevated or lower than normal temperature or blood pressure, or an abnormal finding showing on medical imaging.
RNAFamily of large biological moleculesA hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). This is a single strand of RNA that folds back upon itself. Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA).*As an Amazon Associate I earn from qualifying purchases.