Brugia malayiBrugia malayi is a filarial (arthropod-borne) nematode (roundworm), one of the three causative agents of lymphatic filariasis in humans. Lymphatic filariasis, also known as elephantiasis, is a condition characterized by swelling of the lower limbs. The two other filarial causes of lymphatic filariasis are Wuchereria bancrofti and Brugia timori, which both differ from B. malayi morphologically, symptomatically, and in geographical extent.
Brugia timoriBrugia timori is a filarial (arthropod-borne) nematode (roundworm) which causes the disease "Timor filariasis", or "Timorian filariasis". While this disease was first described in 1965, the identity of Brugia timori as the causative agent was not known until 1977. In that same year, Anopheles barbirostris was shown to be its primary vector. There is no known animal reservoir host.
MosquitoFamily of fliesMosquitoes, the Culicidae, are a family of small flies consisting of 3,600 species. The word mosquito (formed by mosca and diminutive-ito) is Spanish and Portuguese for little fly. Mosquitoes have a slender, segmented body, one pair of wings, three pairs of long hair-like legs, and a specialized, highly elongated set of mouthparts forming a proboscis, adapted for piercing and sucking.
FilarioideaThe Filarioidea are a superfamily of highly specialisedparasiticnematodes. Species within this superfamily are known as filarial worms or filariae (singular filaria). Infections with parasitic filarial worms cause disease conditions generically known as filariasis. Drugs against these worms are known as filaricides. IntroductionFilarioidea all are specialised parasites and the definitive host is always a vertebrate, a mammal, bird, reptile or amphibian, but not a fish.
Mosquito-borne diseaseMosquito-borne diseases or mosquito-borne illnesses are diseases caused by bacteria, viruses or parasites transmitted by mosquitoes. Nearly 700 million people contract mosquito-borne illnesses each year, resulting in over a million deaths.
ElephantiasisElephantiasis, often incorrectly called elephantitis, is the enlargement and hardening of limbs or body parts due to tissue swelling (edema). It is characterised by edema, hypertrophy, and fibrosis of skin and subcutaneous tissues, due to obstruction of lymphatic vessels (lymphedema). It may affect the genitalia.
Wuchereria bancroftiWuchereria bancrofti is a filarial (arthropod-borne) nematode (roundworm) that is the major cause of lymphatic filariasis. It is one of the three parasitic worms, together with Brugia malayi and B. timori, that infect the lymphatic system to cause lymphatic filariasis. These filarial worms are spread by a variety of mosquito vector species.
LymphedemaLymphedema (USA), lymphoedema (UK) also known as lymphatic edema (US)/oedema (UK), is a condition of localized swelling caused by a compromised lymphatic system. The lymphatic system functions as a critical portion of the body's immune system and returns interstitial fluid to the bloodstream. Lymphedema is most frequently a complication of cancer treatment or parasitic infections, but it can also be seen in a number of genetic disorders.
AsymptomaticAsymptomatic (or clinically silent) is an adjective categorising the medical conditions (i.e., injuries or diseases) that patients carry but without experiencing their symptoms, despite an explicit diagnosis (e.g., a positive medical test). Pre-symptomatic is the adjective categorising the time periods during which the medical conditions are asymptomatic.
Parasitic wormParasitic worms, also known as helminths, are a polyphyletic group of large macroparasites; adults can generally be seen with the naked eye. Many are intestinal worms that are soil-transmitted and infect the gastrointestinal tract. Other parasitic worms such as schistosomes reside in blood vessels. Some parasitic worms, including leeches and monogeneans, are ectoparasites – thus, they are not classified as helminths, which are endoparasites.
BreastUpper region of primate torsoThe breasts are two prominences located on the upper ventral region of the torso in humans and other primates. Both sexes develop breasts from the same embryologicaltissues. The relative size and development of the breasts is a major secondary sex distinction between females and males. There is also considerable variation in size between individuals.
MicroscopyMicroscopy is the technical field of using microscopes to view subjects too small to be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of microscopy: optical, electron, and scanning probe microscopy, along with the emerging field of X-ray microscopy.
Blood smearA blood smear, peripheral blood smear or blood film is a thin layer of blood smeared on a glass microscope slide and then stained in such a way as to allow the various blood cells to be examined microscopically. Blood smears are examined in the investigation of hematological (blood) disorders and are routinely employed to look for blood parasites, such as those of malaria and filariasis.*As an Amazon Associate I earn from qualifying purchases.