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Intramuscular injection

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Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle. In medicine, it is one of several methods for parenteral administration of medications. Intramuscular injection may be preferred because muscles have larger and more numerous blood vessels than subcutaneous tissue, leading to faster absorption than subcutaneous or intradermal injections. Medication administered via intramuscular injection is not subject to the first-pass metabolism effect which affects oral medications.

Injection (medicine)Injection (medicine)An injection (often and usually referred to as a "shot" in US English, a "jab" in UK English, or a "jag" in Scottish English and Scots) is the act of administering a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe. An injection is considered a form of parenteral drug administration; it does not involve absorption in the digestive tract.Intradermal injectionIntradermal injectionIntradermal injection (also intracutaneous or intradermic, abbreviated as ID) is a shallow or superficial injection of a substance into the dermis, which is located between the epidermis and the hypodermis. For certain substances, administration via an ID route can result in a faster systemic uptake compared with subcutaneous injections, leading to a stronger immune response to vaccinations, immunology and novel cancer treatments, and faster drug uptake.Blood vesselBlood vesselBlood vessels are the tubular structures of a circulatory system transporting blood in animal bodies. Blood vessels transport blood cells, nutrients, and oxygen to most of the tissues of a body, and also transport waste products and carbon dioxide away from the tissues. Some tissues – such as cartilage, epithelium, and the lens and cornea of the eye – are not supplied with blood vessels, so are termed avascular.Deltoid muscleDeltoid muscleThe deltoid muscle (or musculus deltoideus) is the muscle forming the rounded contour of the human shoulder. It is also known as the 'common shoulder muscle', particularly in other animals such as the domestic cat.Vastus lateralis muscleVastus lateralis muscleThe vastus lateralis (), also called the vastus externus, is the largest and most powerful part of the quadriceps femoris, a muscle in the thigh. Together with other muscles of the quadriceps group, it serves to extend the knee joint, moving the lower leg forward. It arises from a series of flat, broad tendons attached to the femur, and attaches to the outer border of the patella.Gluteal musclesGluteal musclesThe gluteal muscles, often called glutes, are a group of three muscles which make up the gluteal region commonly known as the buttocks: the gluteus maximus, gluteus medius and gluteus minimus. The three muscles originate from the ilium and sacrum and insert on the femur. The functions of the muscles include extension, abduction, external rotation, and internal rotation of the hip joint. StructureThe gluteus maximus is the largest and most of the three gluteal muscles.Route of administrationRoute of administrationIn pharmacology and toxicology, a route of administration (ROA) is the way by which a drug, fluid, poison, or other substance is introduced into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration. Routes can also be classified based on where the target of action is.MuscleMuscleMuscle is a specialised soft tissue, one of the four basic types of animal tissues. There are three types of muscle tissues in vertebrates: skeletal muscle tissue, cardiac muscle tissue, and smooth muscle tissue. Muscle tissue gives skeletal muscles the ability to contract and relax. Muscle tissue contains special contractile proteins called actin and myosin which interact to cause movement.MedicineMedicineDiagnosis, treatment, and prevention of illnessThe Doctor by Sir Luke Fildes (1891)Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment and palliation of their injury or disease, while promoting their health. Medicine encompasses a variety of health care practices which evolved to maintain and restore health through the prevention and treatment of illness and infection.Subcutaneous administrationSubcutaneous administrationSubcutaneous administration is the insertion of medications beneath the skin either by injection or infusion. A subcutaneous injection is administered as a bolus into the subcutis, the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis. The instruments are usually a hypodermic needle and a syringe. Subcutaneous injections are highly effective in administering medications such as insulin, morphine, diacetylmorphine and goserelin.First pass effectFirst pass effectThe first pass effect (FPE), also known as first-pass metabolism (FPM) or presystemic metabolism, is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation. The effect is most associated with orally administeredmedications, but some drugs still undergo first-pass metabolism even when delivered via an alternate route (e.g., IV, IM, etc.).LitreLitreThe litre (Commonwealth spelling) or liter (American spelling) (SI symbols L and l, other symbol used: ℓ) is a metric unit of volume. It is equal to 1 cubic decimetre (dm3), 1000 cubic centimetres (cm3) or 0.001 cubic metres (m3). A cubic decimetre (or litre) occupies a volume of 10 cm × 10 cm × 10 cm (see figure) and is thus equal to one-thousandth of a cubic metre. The original French metric system used the litre as a base unit.

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