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Gene Ontology

The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and gene product attributes; 2) annotate genes and gene products, and assimilate and disseminate annotation data; and 3) provide tools for easy access to all aspects of the data provided by the project, and to enable functional interpretation of experimental data using the GO,…

Model organismModel organismA model organism is a non-humanspecies that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. Model organisms are widely used to research human disease when human experimentation would be unfeasible or unethical.OBO FoundryOBO FoundryThe Open Biological and Biomedical Ontologies (OBO) Foundry is a group of people who build and maintain ontologies related to the life sciences. The OBO Foundry establishes a set of principles for ontology development for creating a suite of interoperable reference ontologies in the biomedical domain. Currently, there are more than a hundred ontologies that follow the OBO Foundry principles.BioinformaticsBioinformaticsBioinformatics ( ) is an interdisciplinary field of science that develops computational methods and software tools for understanding biological data, especially when the data sets are large and complex. Bioinformatics integrates principles from biology, chemistry, physics, computer science, data science, computer programming, information engineering, mathematics, and statistics to analyze and interpret biological data.Gene nomenclatureGene nomenclature is the scientific naming of genes, the units of in living organisms. It is also closely associated with protein nomenclature, as genes and the proteins they code for usually have similar nomenclature. An international committee published recommendations for genetic symbols and nomenclature in 1957.Controlled vocabularyControlled vocabularyA controlled vocabulary provides a way to organize knowledge for subsequent retrieval. Controlled vocabularies are used in subject indexing schemes, subject headings, thesauri, taxonomies, and other knowledge organization systems. Controlled vocabulary schemes mandate the use of predefined, preferred terms that have been preselected by the designers of the schemes, in contrast to natural language vocabularies, which have no such restriction.SpeciesSpeciesBasic unit of taxonomic classification, below genusThe hierarchy of biological classification's eight major taxonomic ranks. A genus contains one or more species. Minor intermediate ranks are not shown.A species (pl. species) is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity.DNA annotationDNA annotationIn molecular biology and genetics, DNA annotation or genome annotation is the process of describing the structure and function of the components of a genome, by analyzing and interpreting them in order to extract their biological significance and understand the biological processes in which they participate. Among other things, it identifies the locations of genes and all the coding regions in a genome and determines what those genes do.GeneGeneSequence of DNA that determines traits in an organismIn biology, the word gene has two meanings. The Mendelian gene is a basic unit of . The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of RNA or protein from a gene), DNA is first copied into RNA.Markup languageMarkup languageA markup language is a text-encoding system which specifies the structure and formatting of a document and potentially the relationships among its parts. Markup can control the display of a document or enrich its content to facilitate automated processing. A markup language is a set of rules governing what markup information may be included in a document and how it is combined with the content of the document in a way to facilitate use by humans and computer programs.TaxonTaxonIn biology, a taxon is a group of one or more populations of an organism, or organisms, as seen by taxonomists to form a biological unit; (taxon: back-formation from taxonomy; pl.: taxa). Although neither is required, a taxon, once its description has become established, is usually known by a particular name and is given a particular ranking.Gene productGene productLook up or in Wiktionary, the free dictionary.Whole genome sequencingWhole genome sequencingSequencing all the DNA of an individual at onceElectropherograms are commonly used to sequence portions of genomes.DNA (deoxyribonucleic acid) is the cell's genetic material, contained in chromosomes within the cell nucleus and mitochondria. Except for certain cells (for example, sperm and egg cells), the cell nucleus contains 23 pairs of chromosomes. A chromosome contains many genes. A gene is a segment of DNA that provides the code to construct a protein or RNA molecule.

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