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Endocrine disruptor

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Chemicals that can interfere with endocrine or hormonal systemsA comparison of the structures of the natural estrogen hormone estradiol (left) and one of the nonyl-phenols (right), a xenoestrogen endocrine disruptorEndocrine disruptors, sometimes also referred to as hormonally active agents, endocrine disrupting chemicals, or endocrine disrupting compounds are chemicals that can interfere with endocrine (or hormonal) systems.

HormoneHormoneA hormone (from Ancient Greek (hormôn)'setting in motion') is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior. Hormones are required for the normal development of animals, plants and fungi.Public healthPublic healthPublic health is "the science of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the determinants of health of a population and the threats it faces is the basis for public health.PhthalatesPhthalatesPhthalates (US: UK: THAL-ates ), or phthalate esters, are esters of phthalic acid. They are colorless, odorless, oily compounds, although commercial samples can be yellowish with faint odors. Being fairly chemically inert and easily produced, they are widely used as plasticizers, i.e., substances added to polymers to increase their flexibility, transparency, durability, and longevity. They are used primarily to soften polyvinyl chloride (PVC).DiethylstilbestrolDiethylstilbestrolChemical compoundPharmaceutical compoundDiethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication. Its use is now rare; in the past, it was widely used for a variety of indications, including pregnancy support for those with a history of recurrent miscarriage, hormone therapy for menopausal symptoms and estrogen deficiency, treatment of prostate cancer and breast cancer, and other uses.EndometriosisEndometriosisEndometriosis is a disease in which tissue similar to the endometrium—the lining of the uterus (womb)—grows elsewhere in the body. The tissue most often grows close to the uterus, such as on the ovaries, fallopian tubes, or the lining of the pelvis. It can also appear on the bowel, bladder, and in some cases on the lungs or skin. Worldwide, endometriosis affects approximately 10% of the female population of reproductive age, representing nearly 200 million women.Endocrine systemEndocrine systemThe endocrine system is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target and regulate distant organs. In vertebrates, the hypothalamus is the neural control center for all endocrine systems. In humans, the major endocrine glands are the thyroid, parathyroid, pituitary, pineal, and adrenal glands, and the (male) testis and (female) ovaries.World Health OrganizationWorld Health OrganizationSpecialized agency of the United NationsThe World Health Organization (WHO) is a specialized agency of the United Nations (UN) which coordinates responses to international public health issues and emergencies. It is headquartered in Geneva, Switzerland, and has six regional offices and 150 field offices worldwide. Only sovereign states are eligible to join, and it is the largest intergovernmental health organization at the international level.Precocious pubertyPrecocious pubertyIn medicine, precocious puberty is puberty occurring at an unusually early age. In most cases, the process is normal in every aspect except the unusually early age and simply represents a variation of normal development. There is early development of secondary sex characters and gametogenesis also starts earlier. Precocious puberty is of two types: true precocious puberty and pseudoprecocious puberty.HomeostasisHomeostasisState of steady internal conditions maintained by living thingsIn biology, homeostasis (in British English also homoeostasis) is the process by which living organisms maintain relatively stable internal physical and chemical conditions despite changes in their internal or external environment.Attention deficit hyperactivity disorderAttention deficit hyperactivity disorderNeurodevelopmental disorderMedical conditionAttention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by symptoms of inattention, hyperactivity, impulsivity, and emotional dysregulation that are excessive and pervasive, impairing in multiple contexts, and developmentally inappropriate. ADHD symptoms arise from executive dysfunction.CognitionCognitionCognition encompasses mental processes that deal with knowledge. It includes psychological activities that acquire, store, retrieve, transform, or apply information. Cognitive processes are a fundamental part of mental life, helping individuals understand and interact with the world. Cognitive processes are typically categorized by their function.Learning disabilityLearning disabilityRange of neurodevelopmental conditionsaquaticaquaticRelated word or term.

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