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Classical genetics

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Branch of genetics Classical genetics is the branch of genetics based solely on visible results of reproductive acts. It is the oldest discipline in the field of genetics, going back to the experiments on Mendelian inheritance by Gregor Mendel who made it possible to identify the basic mechanisms of heredity. Subsequently, these mechanisms have been studied and explained at the molecular level.

Mendelian inheritanceMendelian inheritanceMendelian inheritance (also known as Mendelism) is a type of biologicalinheritance following the principles originally proposed by Gregor Mendel in 1865 and 1866, re-discovered in 1900 by Hugo de Vries and Carl Correns, and later popularized by William Bateson. Its defining characteristic is heavy association with a singular gene. The principles were initially controversial.Gregor MendelGregor MendelGregor Johann Mendel (; German: [ˈmɛndl̩]; Czech: Řehoř Jan Mendel; 20 July 1822 – 6 January 1884) was an Austrian biologist, meteorologist, mathematician, Augustinian friar and abbot of St. Thomas' Abbey in Brno (Brünn), Margraviate of Moravia. Mendel was born in a German-speaking family in the Silesian part of the Austrian Empire (today's Czech Republic) and gained posthumous recognition as the founder of the modern science of genetics.GeneGeneIn biology, the word gene has two meanings. The Mendelian gene is a basic unit of . The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of RNA or protein from a gene), DNA is first copied into RNA. RNA can be directly functional or be the intermediate template for the synthesis of a protein.GeneticsGeneticsGenetics is the study of genes, genetic variation, and heredity in organisms. It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time.Molecular biologyMolecular biologyMolecular biology is a branch of biology that seeks to understand the molecular structures and chemical processes that are the basis of biological activity within and between cells. It is centered largely on the study of nucleic acids (such as DNA and RNA) and proteins.Genetic linkageGenetic linkageGenetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction. Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more linked than markers that are far apart.ChromosomeChromosomeDNA molecule containing genetic material of a cellDifferent representations of chromosomesMain parts of a condensed chromosomeCondensed chromosome (purple rod) inside a bone marrow erythrokaryocyte undergoing mitosisDiagram of a duplicated and condensed metaphase eukaryotic chromosome: ChromatidCentromereShort armLong armA chromosome is a package of DNA containing part or all of the genetic material of an organism.Genetic codeGenetic codeGenetic code is a set of rules used by living cells to translate information encoded within genetic material (DNA or RNA sequences of nucleotide triplets or codons) into proteins. Translation is accomplished by the ribosome, which links proteinogenic amino acids in an order specified by messenger RNA (mRNA), using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time.MeiosisMeiosisCell division producing haploid gametesIn meiosis, the chromosomes duplicate (during interphase) and homologous chromosomes exchange genetic information (chromosomal crossover) during the first division, called meiosis I. The daughter cells divide again in meiosis II, splitting up sister chromatids to form haploid gametes.EukaryoteEukaryoteDomain of life whose cells have nucleiThe eukaryotes () are cellularorganisms of the domainEukaryota or Eukarya, which have a distinct cell nucleus (formed by a nuclear membrane), membrane-bound organelles and organization supported by a cytoskeleton. Extant eukaryotes are traditionally grouped into four kingdoms: animals, plants, fungi and protists.Plant breedingPlant breedingPlant breeding is the science of changing the traits of plants in order to produce desired characteristics. It is used to improve the quality of plant products for use by humans and animals. The goals of plant breeding are to produce crop varieties that boast unique and superior traits for a variety of applications.Molecular cloningMolecular cloningMolecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The use of the word cloning refers to the fact that the method involves the replication of one molecule to produce a population of cells with identical DNA molecules.

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