Skin and skin structure infectionSkin and skin structure infections (SSSIs), also referred to as skin and soft tissue infections (SSTIs), or, in the case of acute ones of bacterial cause, acute bacterial skin and skin structure infections (ABSSSIs), are infections of skin and associated soft tissues (such as loose connective tissue and mucous membranes). Historically, the pathogen involved has most frequently been a bacterial species.
CephalosporinThe cephalosporins (sg. ) are a class of β-lactam antibiotics originally derived from the fungal genus Acremonium, which was previously known as Cephalosporium. Together with cephamycins, they constitute a subgroup of β-lactam antibiotics called cephems. Cephalosporins were discovered in 1945, and first sold in 1964. DiscoveryThe aerobicmold which yielded cephalosporin C was found in the sea near Cagliari, Sardinia, by the ItalianpharmacologistGiuseppe Brotzu in July 1945.
Methicillin-resistant Staphylococcus aureusMethicillin-resistant Staphylococcus aureus (MRSA) is a group of Staphylococcus aureus strains that are resistant to β-lactam antibiotics. The β-lactam group is a broad-spectrum group of antibiotics that includes several widely used drugs, including methicillin, oxacillin, and cephalosporins. Therefore, MRSA is responsible for several difficult-to-treat infections in humans. It caused more than 100,000 deaths worldwide attributable to antimicrobial resistance in 2019.Community-acquired pneumoniaCommunity-acquired pneumonia (CAP) refers to pneumonia contracted by a person outside of the healthcare system. In contrast, hospital-acquired pneumonia (HAP) is seen in patients who are in a hospital or who have recently been hospitalized in the last 48 hours.
AntibioticAntimicrobial substance active against bacteriaAn antibiotic is a type of antimicrobial substance which is active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria.
Forest LaboratoriesForest Laboratories was a company in the pharmaceutical industry incorporated in Delaware, with its principal office in New York City. It was known for licensing European pharmaceuticals for sale in the United States. On July 1, 2014, the company was acquired by Actavis (now Allergan). HistoryThe company was founded by Hans Lowey in 1956 as a small laboratory service company. In 1967, the company became a public company via an initial public offering.
PneumoniaPneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severity of the condition is variable. Pneumonia is usually caused by infection with viruses or bacteria, and less commonly by other microorganisms. Identifying the responsible pathogen can be difficult.
Takeda Pharmaceutical CompanyThe Takeda Pharmaceutical Company Limited (武田薬品工業株式会社, Takeda Yakuhin Kōgyō kabushiki gaisha) is a Japanese multinationalpharmaceutical company. It is the third largest pharmaceutical company in Asia, behind Sinopharm and Shanghai Pharmaceuticals, and one of the top 20 largest pharmaceutical companies in the world by revenue (top 10 following its merger with Shire).
Food and Drug AdministrationThe Food and Drug Administration (FDA) is a federal agency of the United States Department of Health and Human Services (HHS).International nonproprietary nameAn international nonproprietary name (INN) is an official generic and nonproprietary name given to a pharmaceutical substance or an active ingredient, encompassing compounds, peptides and low-molecular-weight proteins (e.g., insulin, hormones, cytokines), as well as complex biological products, such as those used for gene therapy. INNs are intended to make communication more precise by providing a unique standard name for each active ingredient, to avoid prescribing errors.
Gram-negative bacteriaGram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. Their defining characteristic is that their cell envelope consists of a thin peptidoglycan cell wall sandwiched between an inner (cytoplasmic) membrane and an outer membrane. These bacteria are found in all environments that support life on Earth.
Gram-positive bacteriaGram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall. Gram-positive bacteria have a thick layer of peptidoglycan in their cell wall which retains the stain, unlike the thin layer of peptidoglycan in gram-negative bacteria that does not retain the stain.
CephalosporinThe cephalosporins (sg. ) are a class of β-lactam antibiotics originally derived from the fungal genus Acremonium, which was previously known as Cephalosporium. Together with cephamycins, they constitute a subgroup of β-lactam antibiotics called cephems. Cephalosporins were discovered in 1945, and first sold in 1964. DiscoveryThe aerobicmold which yielded cephalosporin C was found in the sea near Cagliari, Sardinia, by the ItalianpharmacologistGiuseppe Brotzu in July 1945.Methicillin-resistant Staphylococcus aureusMethicillin-resistant Staphylococcus aureus (MRSA) is a group of Staphylococcus aureus strains that are resistant to β-lactam antibiotics. The β-lactam group is a broad-spectrum group of antibiotics that includes several widely used drugs, including methicillin, oxacillin, and cephalosporins. Therefore, MRSA is responsible for several difficult-to-treat infections in humans. It caused more than 100,000 deaths worldwide attributable to antimicrobial resistance in 2019.Community-acquired pneumoniaCommunity-acquired pneumonia (CAP) refers to pneumonia contracted by a person outside of the healthcare system. In contrast, hospital-acquired pneumonia (HAP) is seen in patients who are in a hospital or who have recently been hospitalized in the last 48 hours.AntibioticAntimicrobial substance active against bacteriaAn antibiotic is a type of antimicrobial substance which is active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria.Forest LaboratoriesForest Laboratories was a company in the pharmaceutical industry incorporated in Delaware, with its principal office in New York City. It was known for licensing European pharmaceuticals for sale in the United States. On July 1, 2014, the company was acquired by Actavis (now Allergan). HistoryThe company was founded by Hans Lowey in 1956 as a small laboratory service company. In 1967, the company became a public company via an initial public offering.PneumoniaPneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severity of the condition is variable. Pneumonia is usually caused by infection with viruses or bacteria, and less commonly by other microorganisms. Identifying the responsible pathogen can be difficult.Takeda Pharmaceutical CompanyThe Takeda Pharmaceutical Company Limited (武田薬品工業株式会社, Takeda Yakuhin Kōgyō kabushiki gaisha) is a Japanese multinationalpharmaceutical company. It is the third largest pharmaceutical company in Asia, behind Sinopharm and Shanghai Pharmaceuticals, and one of the top 20 largest pharmaceutical companies in the world by revenue (top 10 following its merger with Shire).Food and Drug AdministrationThe Food and Drug Administration (FDA) is a federal agency of the United States Department of Health and Human Services (HHS).International nonproprietary nameAn international nonproprietary name (INN) is an official generic and nonproprietary name given to a pharmaceutical substance or an active ingredient, encompassing compounds, peptides and low-molecular-weight proteins (e.g., insulin, hormones, cytokines), as well as complex biological products, such as those used for gene therapy. INNs are intended to make communication more precise by providing a unique standard name for each active ingredient, to avoid prescribing errors.Gram-negative bacteriaGram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. Their defining characteristic is that their cell envelope consists of a thin peptidoglycan cell wall sandwiched between an inner (cytoplasmic) membrane and an outer membrane. These bacteria are found in all environments that support life on Earth.Gram-positive bacteriaGram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall. Gram-positive bacteria have a thick layer of peptidoglycan in their cell wall which retains the stain, unlike the thin layer of peptidoglycan in gram-negative bacteria that does not retain the stain.*As an Amazon Associate I earn from qualifying purchases.