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Brain mapping

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Brain mapping is a set of neuroscience techniques predicated on the mapping of (biological) quantities or properties onto spatial representations of the (human or non-human) brain resulting in maps. According to the definition established in 2013 by Society for Brain Mapping and Therapeutics (SBMT), brain mapping is specifically defined, in summary, as the study of the anatomy and function of the brain and spinal cord through the use of imaging, immunohistochemistry, molecular & optogenetics, stem cell and cellular…

NeuroimagingNeuroimagingNeuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Increasingly it is also being used for quantitative research studies of brain disease and psychiatric illness.NeuroscienceNeuroscienceScientific study of the nervous systemDrawing by Santiago Ramón y Cajal (1899) of neurons in the pigeon cerebellumNeuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders.Society for Brain Mapping and TherapeuticsThe Society for Brain Mapping and Therapeutics (SBMT) is a non-profit biomedical association (501c6) principally concerned with Brain Mapping and Intra-operative Surgical planning. International Brain Mapping and Intraoperative Surgical planning Foundation (IBMISPF) DBA The Brain Mapping Foundation provides funding to members of the society.BrainBrainOrgan central to the nervous systemThe brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrateanimals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for special senses such as vision, hearing, and olfaction.OptogeneticsOptogeneticsControlling biological cells with lightOptogenetics is a biological technique used to characterize and manipulate the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes in the target brain cells. A specialization of this field is nano-optogenetics. On the level of individual cells, light-activated enzymes and transcription factors allow precise control of biochemical signaling pathways.AnatomyAnatomyStudy of the structure of organismsOne of the large, detailed illustrations in Andreas Vesalius's De humani corporis fabrica 16th century, marking the rebirth of anatomyAnatomy (from Ancient Greek ἀνατομή (anatomḗ) 'dissection') is the branch of morphology concerned with the study of the internal and external structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things.Spinal cordSpinal cordThe spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal cord is hollow and contains a structure called the central canal, which contains cerebrospinal fluid. The spinal cord is also covered by the meninges and enclosed by the neural arches.Stem cellStem cellUnspecialized biological cell that can become specializedIn multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each.ImmunohistochemistryImmunohistochemistryImmunohistochemistry is a form of immunostaining. It involves the process of selectively identifying antigens in cells and tissue, by exploiting the principle of antibodies binding specifically to antigens in biological tissues. Albert Hewett Coons, Ernest Berliner, Norman Jones and Hugh J Creech was the first to develop immunofluorescence in 1941. This led to the later development of immunohistochemistry.MapMapIn cartography, a map is a representation or abstraction of geographic reality. Maps are used for a wide range of purposes, including navigation, scientific research, governance, and warfare. A common use is route planning, which enables users to find their way to their destination. Specialized maps, called charts, are used for nautical navigation (nautical charts) and aviation (aeronautical charts).Molecular geneticsMolecular geneticsMolecular genetics is a branch of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the structure and/or function of genes in an organism's genome using genetic screens.Cell biologyCell biologyCell biology, cellular biology, or cytology, is the branch of biology that studies the structure, function, and behavior of the cells. All organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of an organism. Cell biology encompasses both prokaryotic and eukaryotic cells, with subtopics including the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition.

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