Włodzimierz Wojciech Ptak (2 November 1928 – 28 May 2019) was a Polish
immunologist and
microbiologist
A microbiologist (from Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of microscopic organisms such as bacteria, algae, fungi, and some types of par ...
,
professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other tertiary education, post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin ...
of
medical sciences
Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pract ...
, member of the
Polish Academy of Sciences
The Polish Academy of Sciences (, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society of distinguished scholars a ...
and the
Polish Academy of Learning
The Polish Academy of Arts and Sciences or Polish Academy of Learning (, PAU), headquartered in Kraków and founded in 1872, is one of two institutions in contemporary Poland having the nature of an academy of sciences (the other being the Po ...
, professor and Vice-Rector at the
Medical Academy in Kraków, later transformed into the Jagiellonian University Medical College, visiting professor at
Yale University
Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United Stat ...
.
In his scientific work, he studied mainly the regulatory mechanisms of the
immune response
An immune response is a physiological reaction which occurs within an organism in the context of inflammation for the purpose of defending against exogenous factors. These include a wide variety of different toxins, viruses, intra- and extracellula ...
. Together with
Richard K. Gershon, he co-authored the discovery of
regulatory T cell
The regulatory T cells (Tregs or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain immune tolerance, tolerance to self-antigens, and prevent autoimmune disease. Treg  ...
s. He published more than two hundred research papers, and was one of the most frequently cited Polish scientists in the field of
biomedicine
Biomedicine (also referred to as Western medicine, mainstream medicine or conventional medicine) after 1965.
A graduate of the Medical Academy in Kraków, he was forcibly drafted into the
Polish Army
The Land Forces () are the Army, land forces of the Polish Armed Forces. They currently contain some 110,000 active personnel and form many components of the European Union and NATO deployments around the world. Poland's recorded military histor ...
between 1952 and 1957. He obtained
Ph.D. in 1962 at the
Medical Academy in Szczecin. In 1967, he received
British Council
The British Council is a British organisation specialising in international cultural and educational opportunities. It works in over 100 countries: promoting a wider knowledge of the United Kingdom and the English language (and the Welsh lang ...
scholarship to the
National Institute for Medical Research
The National Institute for Medical Research (NIMR), was a medical research institute based in Mill Hill, on the outskirts of north London, England. It was funded by the Medical Research Council (MRC);
In 2016, the NIMR became part of the new F ...
in London.
From 1974 until 1999, he was a visiting professor at
Yale University
Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United Stat ...
, meanwhile standing as the Vice-Rector of the Medical Academy in Kraków (1978–1981) and a member of the Presidium of the
International Union of Immunological Societies
The International Union of Immunological Societies (IUIS), a member of the International Council for Science, is an organization which serves as an umbrella organization for many national and regionally grouped immunological societies. The organ ...
(1983–1986). He was a member of the Presidium (1978–1984) and a Chairman (1988–1990) of the Scientific Council by the
Minister of Health and Welfare of Poland. Later, he was appointed a Secretary (1989–1995) and Vice-President (until 2008) of the Medical Faculty of the Polish Academy of Learning.
He received several awards and state distinctions, including the Knight's Cross (1977) and the Commander's Cross (1997) of the
Polonia Restituta
The Order of Polonia Restituta (, ) is a Polish state order established 4 February 1921. It is conferred on both military and civilians as well as on foreigners for outstanding achievements in the fields of education, science, sport, culture, ...
.
Life and work
1928–1952: Youth
He was born in 1928 in
Kraków
, officially the Royal Capital City of Kraków, is the List of cities and towns in Poland, second-largest and one of the oldest cities in Poland. Situated on the Vistula River in Lesser Poland Voivodeship, the city has a population of 804,237 ...
as the son of Wojciech Ptak (1888–1946), an engineer and a graduate of the
Lviv Polytechnic
Lviv Polytechnic National University () is a public university in Lviv, Ukraine, founded in 1816. According to the Times Higher Education, as of 2024, it ranks first as a technical institution of higher education and second among all instit ...
, and Maria Ptak (née Krawczyk; 1904–1986), an employee in ''kasa chorych'', a public health insurance corporation. The father, as his son recalled, was a tough, demanding and strict man, fluent in French and German language.
His grandparents were
Franciszek Ptak (1859–1936), an innkeeper,
peasant movement
A peasant movement is a social movement involved with the agricultural policy, which claims peasants rights.
Peasant movements have a long history that can be traced to the numerous peasant uprisings that occurred in various regions of the wor ...
activist and a member of the
Diet of Galicia and Lodomeria
The Diet of the Kingdom of Galicia and Lodomeria, and of the Grand Duchy of Cracow was the regional assembly of the Kingdom of Galicia and Lodomeria, a crown land of the Austrian Empire, and later Austria-Hungary. In the history of the Polish ...
,
and Józef Krawczyk (1865–1942), a foreman in the cigarette factory “Cygar fabryka” at Dolnych Młynów Street in Kraków.
Włodzimierz had a younger sister, Wanda Ptak-Kollat (1930–1984), a master engineer in roads and bridges and a graduate of
Kraków Polytechnic
, officially the Royal Capital City of Kraków, is the List of cities and towns in Poland, second-largest and one of the oldest cities in Poland. Situated on the Vistula River in Lesser Poland Voivodeship, the city has a population of 804,237 ...
.
In 1936, Wojciech Ptak was offered a work in high office in the French-Polish railway company in
Bydgoszcz
Bydgoszcz is a city in northern Poland and the largest city in the historical region of Kuyavia. Straddling the confluence of the Vistula River and its bank (geography), left-bank tributary, the Brda (river), Brda, the strategic location of Byd ...
, hence the Ptak family moved there. In 1939, after the outbreak of
World War II
World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
, the Ptaks returned to Kraków, as Włodzimierz recalled: “We returned from a four-room apartment to a single room with a kitchen. We've lost everything. My father fell ill. He died of a heart attack just after the war, before my high school graduation.”
In his youth, Włodzimierz Ptak learned to play the
violin
The violin, sometimes referred to as a fiddle, is a wooden chordophone, and is the smallest, and thus highest-pitched instrument (soprano) in regular use in the violin family. Smaller violin-type instruments exist, including the violino picc ...
. As a child, he attended the Bydgoszcz Conservatory of Music. As a teenager, in
German-occupied Kraków, he was a student of Stanisław Syrewicz, the concert master of the
Kraków Philharmonic. At the time, he attended the trade school at Brzozowa Street in Kraków, also taking
secret Latin lessons from professor Pardiak.
From an early age, he was interested in
biology
Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and ...
and
astronomy
Astronomy is a natural science that studies celestial objects and the phenomena that occur in the cosmos. It uses mathematics, physics, and chemistry in order to explain their origin and their overall evolution. Objects of interest includ ...
. He read a lot about nature. The book that he said attracted his attention particularly was ''The Natural History of One Protozoan'' by
Jan Dembowski. As a boy, Włodzimierz kept himself a large collection of protozoa at home, and next to it a dog, a cat, a canary, a fish and a white mouse. Together with a friend of his, using glasses purchased at a local optical store, they constructed a simple
telescope
A telescope is a device used to observe distant objects by their emission, Absorption (electromagnetic radiation), absorption, or Reflection (physics), reflection of electromagnetic radiation. Originally, it was an optical instrument using len ...
to observe the night sky.
From 1943, Ptak worked physically at the construction of the road from
Dębniki to
Prokocim, and later as a hand of a car mechanic in a workshop at Grzegórzecka Street in Kraków.
He recalled: “During the war, when I was thirteen, I was searching through my grandfather's large library, and I came across a book that largely influenced the formation of my worldview. ''The Studies on Social Doctrines of Christianity'' by
Yves Guyot
Yves Guyot (6 September 184322 February 1928) was a French politician and economist. Biography
He was born at Dinan. Educated at Rennes, he took up the profession of journalism, coming to Paris in 1867. He was for a short period editor-in-chief of ...
contributed to the fact that I am
irreligious
Irreligion is the absence or rejection of religious beliefs or practices. It encompasses a wide range of viewpoints drawn from various philosophical and intellectual perspectives, including atheism, agnosticism, religious skepticism, rationa ...
.”
Ptak attended the
Jan III Sobieski High School in Kraków, but due to a conflict with a mathematics teacher in the final year, he moved to the Henryk Sienkiewicz High School. There, he passed the
matura exam in 1946.
Also in 1946, he enrolled to the medical studies at the
Medical Academy in Kraków. There, among his teachers was
Henryk Niewodniczański
Henryk Niewodniczański (1900–1968) was a Polish physicist, professor at the Jagiellonian University and the creator and director of the Institute of Nuclear Physics in Kraków.
Life and career
He graduated from the Stefan Batory University ...
, who awarded Ptak with an excellent degree in exam in physics. At the end of the studies, Ptak's interests began to focus primarily on microbiology and bacteriology. He graduated in 1952.
During the studies, to support himself financially, he founded a music group with colleagues from different universities, and earned money by playing at seasonal parties and weddings.
1952–1970: In the army, Ph.D.
In 1952, immediately after the graduation, Ptak was forcibly drafted into the
Polish People's Army
The Polish People's Army (, ; LWP) was the second formation of the Polish Armed Forces in the East during the latter stages of the Second World War (1943–1945), and subsequently the armed forces of the Polish communist state (1945–1989 ...
. Soon after, he was transferred to the Służba Polsce (Service to Poland; SP), a state paramilitary organization for young people. Ptak spent a total of five years in the army and SP.
He received an initial allocation in
Jelenia Góra
Jelenia Góra (; ; ) is a historic city in southwestern Poland, within the historical region of Lower Silesia. Jelenia Góra is situated in the Lower Silesian Voivodeship, close to the Karkonosze mountain range running along the Polish-Czech bo ...
, where he worked on the production of viscose fibers. Then he was accepted by
Ludwik Hirszfeld
Ludwik Hirszfeld (; 5 August 1884 – 7 March 1954) was a Polish microbiologist and serologist. He is considered a co-discoverer of the inheritance of ABO blood types.
Life
He was a cousin of Aleksander Rajchman, a Polish mathematician, and ...
as a volunteer at the Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences, but he remained there only for a few weeks. He was transferred to
Katowice
Katowice (, ) is the capital city of the Silesian Voivodeship in southern Poland and the central city of the Katowice urban area. As of 2021, Katowice has an official population of 286,960, and a resident population estimate of around 315,000. K ...
, where he worked as a medical controller of the SP units in
Upper Silesia
Upper Silesia ( ; ; ; ; Silesian German: ; ) is the southeastern part of the historical and geographical region of Silesia, located today mostly in Poland, with small parts in the Czech Republic. The area is predominantly known for its heav ...
and
Opole
Opole (; ; ; ) is a city located in southern Poland on the Oder River and the historical capital of Upper Silesia. With a population of approximately 127,387 as of the 2021 census, it is the capital of Opole Voivodeship (province) and the seat of ...
. Practically, this meant constant mobility and work in various facilities throughout the region.
In 1954, Ptak was relocated to
Bydgoszcz
Bydgoszcz is a city in northern Poland and the largest city in the historical region of Kuyavia. Straddling the confluence of the Vistula River and its bank (geography), left-bank tributary, the Brda (river), Brda, the strategic location of Byd ...
, where he worked as a pediatrician for two months, though he had no previous experience in direct work with patients. Then, at his own request, he was transferred to
Szczecin
Szczecin ( , , ; ; ; or ) is the capital city, capital and largest city of the West Pomeranian Voivodeship in northwestern Poland. Located near the Baltic Sea and the Poland-Germany border, German border, it is a major port, seaport, the la ...
, where he wanted to continue his education.
He began to write requests for release from the army. In 1955, during a two-month sick leave, he worked at the Department of Microbiology at the Medical Academy in Kraków, where he conducted research together with Jan Bóbr. In 1957, he was dismissed from the service in the army and began work at the Department of Pathology at the
Medical Academy in Szczecin. There, in 1961, he submitted his doctoral thesis and moved permanently to Kraków, where his mother lived.
He obtained
Ph.D. in
pathology
Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
in 1962 at the Medical Academy in Szczecin. He recalled: “Because of the army, I was already 34 years old. I wasted five years of life. At this age two of my first collaborators were already appointed associate professors”.
In 1967, Ptak left for a ten-month
British Council
The British Council is a British organisation specialising in international cultural and educational opportunities. It works in over 100 countries: promoting a wider knowledge of the United Kingdom and the English language (and the Welsh lang ...
scholarship to the
National Institute for Medical Research
The National Institute for Medical Research (NIMR), was a medical research institute based in Mill Hill, on the outskirts of north London, England. It was funded by the Medical Research Council (MRC);
In 2016, the NIMR became part of the new F ...
in London.
1970–1999: Between Kraków and New Haven
He passed his
habilitation
Habilitation is the highest university degree, or the procedure by which it is achieved, in Germany, France, Italy, Poland and some other European and non-English-speaking countries. The candidate fulfills a university's set criteria of excelle ...
exam in the field of pathology in 1970.
Julian Aleksandrowicz was one of the reviewers of his work. In 1976 Ptak was given the title of full professor.
Over the years, he held the position of Deputy Director of the Institute of Microbiology, Head of the Department of Experimental and Clinical Immunology of the Institute of Microbiology, and Head of the Department of Immunology of the Medical Academy in Kraków. Between 1978 and 1981, Ptak was the Vice-Rector of the Medical Academy in Kraków.
From 1974 until 1999, he was a
visiting professor
In academia, a visiting scholar, visiting scientist, visiting researcher, visiting fellow, visiting lecturer, or visiting professor is a scholar from an institution who visits a host university to teach, lecture, or perform research on a topic fo ...
at the Department of Immunology, Department of Internal Medicine at
Yale University
Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United Stat ...
. Altogether, he spent there more than seven years by submitting twenty-six visits.
At Yale, his direct superior was
Richard K. Gershon, with whom Ptak collaborated extensively and made friends.
Ptak believed that his frequent visits to the United States from a country of the
Soviet Bloc
The Eastern Bloc, also known as the Communist Bloc (Combloc), the Socialist Bloc, the Workers Bloc, and the Soviet Bloc, was an unofficial coalition of communist states of Central and Eastern Europe, Asia, Africa, and Latin America that were a ...
, which Polish People's Republic then was, were enabled by the-then Rector of the Medical Academy in Kraków, Tadeusz Popiela: “It was not because the regime loved us that we left the country whenever we wanted. It was because Popiela often handed for us, and sent us on his own responsibility.”
Ptak stopped visiting Yale at the end of the 1990s, in spite of the repeated invitations. He explained it with his age: “In Kraków I can adjust my work time: three–four hours a day. There
t YaleI worked fourteen–sixteen hours a day. That I cannot do any more.”
In 1986, he was elected a correspondent member of the
Polish Academy of Sciences
The Polish Academy of Sciences (, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society of distinguished scholars a ...
(PAN). In 1989, he was elected a member of the
Polish Academy of Learning
The Polish Academy of Arts and Sciences or Polish Academy of Learning (, PAU), headquartered in Kraków and founded in 1872, is one of two institutions in contemporary Poland having the nature of an academy of sciences (the other being the Po ...
.
He was a member of the Committee for Immunology of the Polish Academy of Sciences, as well as a member of the Presidium of the
International Union of Immunological Societies
The International Union of Immunological Societies (IUIS), a member of the International Council for Science, is an organization which serves as an umbrella organization for many national and regionally grouped immunological societies. The organ ...
(1983–1986). In 1989, he was elected a member of the Polish Immunological Society, that later awarded him with an honorary membership. Ptak was also a member of the Presidium (1978–1984) and Chairman (1988–1990) of the Scientific Council by the
Minister of Health and Welfare of Poland. Later, he was appointed the Secretary (1989–1995) and a Vice-President (until 2008) of the Medical Faculty of the Polish Academy of Learning.
In his scientific work, he studied mainly the regulatory mechanisms of the
immune response
An immune response is a physiological reaction which occurs within an organism in the context of inflammation for the purpose of defending against exogenous factors. These include a wide variety of different toxins, viruses, intra- and extracellula ...
. He published more than two hundred original
research papers
Research paper may refer to:
* Academic paper (also called ''scholarly paper''), which is in academic journals and contains original research results or reviews existing results or shows a totally new invention
* Capstone project or synthesis pr ...
in international
peer review
Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work (:wiktionary:peer#Etymology 2, peers). It functions as a form of self-regulation by qualified members of a profession within the ...
ed
journals, and was one of the most frequently cited Polish scientists in the field of biomedicine after 1965.
Together with Richard K. Gershon, he was the co-author of the discovery of
regulatory T cell
The regulatory T cells (Tregs or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain immune tolerance, tolerance to self-antigens, and prevent autoimmune disease. Treg  ...
s. Beside, he participated in describing the regulatory functions of
gamma delta T cell
Gamma delta T cells (γδ T cells) are T cells that have a γδ T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed of two glycoprotein chains called α (alpha) and β (beta) TCR chains. In contrast, ...
s, and conducted research on the mechanisms of the early phase of cellular reactions, as well as the study of the regulatory functions of
small interfering RNA
Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA, double-stranded non-coding RNA, non-coding RNA, RNA molecules, typically 20–24 base pairs in length, similar to microR ...
.
1999–2019: Late work
He was a member of the Editorial Board of the ''
European Journal of Immunology'' (1985–2004),
as well as a member of the Scientific Council of the
Institute of Pharmacology of the Polish Academy of Sciences (1994–2018).
He authored a textbook "''Podstawy immunologii''" (''Basics of Immunology'') in Polish. First published in 1976, it was followed-up by a number of re-editions, co-authored by Maria Ptak and Marian Szczepanik (1987, 1999, 2009, 2017).
Ptak was also active as an academic teacher. He was a promoter in ten doctoral dissertations.
He died in Kraków on 28 May 2019 at the age of 90, and was buried at the
Rakowicki Cemetery
Rakowicki Cemetery (English: ; ) is a historic necropolis and a cultural heritage monument located on 26 Rakowicka Street in Kraków, Poland. It lies within the Administrative District No. 1 ''Stare Miasto'' meaning "Old Town" – distinct from ...
on 3 June 2019, in the family grave.
Personal life
Over the years, he made friends with artists and intellectuals, such as
Zbigniew Cybulski
Zbigniew Hubert Cybulski (; 3 November 1927 – 8 January 1967) was a Polish film and theatre actor, one of the best-known and most popular personalities of the post-World War II history of Poland.
He is known for portraying young rebels i ...
, Adam Walaciński, Artur Maria Swinarski (in the 1950s), Franciszek Studnicki, Adam Macedoński (in the 1960s),
Krzysztof Penderecki
Krzysztof Eugeniusz Penderecki (; 23 November 1933 – 29 March 2020) was a Polish composer and conductor. His best-known works include '' Threnody to the Victims of Hiroshima'', Symphony No. 3, his '' St Luke Passion'', '' Polish Requiem'', '' ...
and
Alexander Schenker (in the 1970s).
He was an
atheist
Atheism, in the broadest sense, is an absence of belief in the existence of deities. Less broadly, atheism is a rejection of the belief that any deities exist. In an even narrower sense, atheism is specifically the position that there no ...
and defined his worldview as
leftist
Left-wing politics describes the range of political ideologies that support and seek to achieve social equality and egalitarianism, often in opposition to social hierarchy either as a whole or of certain social hierarchies. Left-wing politi ...
.
Among his hobbies were, among others,
history
History is the systematic study of the past, focusing primarily on the Human history, human past. As an academic discipline, it analyses and interprets evidence to construct narratives about what happened and explain why it happened. Some t ...
,
religion studies and
philosophy
Philosophy ('love of wisdom' in Ancient Greek) is a systematic study of general and fundamental questions concerning topics like existence, reason, knowledge, Value (ethics and social sciences), value, mind, and language. It is a rational an ...
. He was cast in a small role in a 2016
short film
A short film is a film with a low running time. The Academy of Motion Picture Arts and Sciences (AMPAS) defines a short film as "an original motion picture that has a running time of not more than 40 minutes including all credits". Other film o ...
''Hens'' (''Kury''). He was married three times, and had one daughter in the second marriage.
Selected papers
*
*
*
*
*
*
*
Awards and honors
* Minister of Health of Poland Award, first degree (seven times, 1973–2009)
* Scientific Secretary of the Polish Academy of Sciences Award (1973, 1984)
* Knight's Cross of
Polonia Restituta
The Order of Polonia Restituta (, ) is a Polish state order established 4 February 1921. It is conferred on both military and civilians as well as on foreigners for outstanding achievements in the fields of education, science, sport, culture, ...
(1977)
* Jędrzej Śniadecki Award (1978)
* Alfred Jurzykowski Foundation Award (1981)
* Award of the Faculty of Medical Sciences of the Polish Academy of Sciences, first degree (1982)
* State Prize of the Polish People's Republic (1984)
* Meritorious Teacher of the Polish People's Republic Award (1984)
* “Gloria Medicinae” Medal awarded by the
Polish Medical Association (1992)
* Prime Minister of Poland Award (1996)
* Commander's Cross of Polonia Restituta (1998)
*
Minister of National Education of Poland Award (1999)
* Jagiellonian Laurel awarded by the
Jagiellonian University
The Jagiellonian University (, UJ) is a public research university in Kraków, Poland. Founded in 1364 by Casimir III the Great, King Casimir III the Great, it is the oldest university in Poland and one of the List of oldest universities in con ...
(1999)
* Honoris Gratia Award awarded by the
President of Kraków (2016)
Source
Notes
References
Bibliography
*
{{DEFAULTSORT:Ptak, Wlodzimierz
Polish microbiologists
Polish immunologists
Members of the Polish Academy of Sciences
Members of the Polish Academy of Learning
Jagiellonian University alumni
Academic staff of Jagiellonian University
Yale School of Medicine faculty
1928 births
2019 deaths
Physicians from Kraków
Knights of the Order of Polonia Restituta
Commanders of the Order of Polonia Restituta
Polish atheists
Burials at Rakowicki Cemetery
Recipients of the State Award Badge (Poland)