What A Difference A Day Makes (Grey's Anatomy)
   HOME

TheInfoList



OR:

"What a Difference a Day Makes" is the twenty-second episode of the fifth season of the
American television Television is one of the Mass media in the United States, major mass media outlets in the United States. In 2011, 96.7% of households owned television sets; about 114,200,000 American households owned at least one television set each in August ...
medical drama A medical drama is a Television film, television movie or film in which events center upon a hospital, clinic, doctor's office, a paramedic, or any other medical topic or environment. Most recent medical drama (film and television), dramatic progra ...
, ''
Grey's Anatomy ''Grey's Anatomy'' is an American medical drama television series focusing on the personal and professional lives of surgical internship (medicine), interns, residency (medicine), residents, and attending physician, attendings at the fictional ...
'' and the show's 100th episode overall. It is written by series creator
Shonda Rhimes Shonda Lynn Rhimes (born January 13, 1970) is an American television producer and screenwriter, and founder of the production company Shondaland. Inducted into the Television Hall of Fame and NAB Broadcasting Hall of Fame, Rhimes became known ...
and directed by
Rob Corn Robert L. Corn (born August 12, 1955) is an American television producer and director best known for Girls Club (TV series), Girls Club (2002), The District (2000), The Resident (TV series), The Resident (2018), Grey's Anatomy (2005), Chicago Hop ...
, the episode was originally broadcast on the
American Broadcasting Company The American Broadcasting Company (ABC) is an American Commercial broadcasting, commercial broadcast Television broadcaster, television and radio Radio network, network that serves as the flagship property of the Disney Entertainment division ...
(ABC) in the United States on May 7, 2009. ''Grey's Anatomy'' centers around a group of young doctors in training. In this episode, a wedding takes place. The episode received widespread critical acclaim, with Heigl and Chambers' performances receiving high praise. The initial airing was viewed by 15.326 million people and garnered a 5.3/14 Nielsen rating/share in the 18–49 demographic.


Plot

The episode opens to a
voice-over Voice-over (also known as off-camera or off-stage commentary) is a production technique used in radio, television, filmmaking, theatre, and other media in which a descriptive or expository voice that is not part of the narrative (i.e., non- ...
by
Izzie Stevens Isobel Katherine Stevens, M.D. is a fictional character from the medical drama television series ''Grey's Anatomy'', which airs on the American Broadcasting Company (ABC) in the United States. The character was created by series producer Shonda R ...
(
Katherine Heigl Katherine Heigl ( ; born November 24, 1978) is an American actress and model. She portrayed Izzie Stevens, Dr. Izzie Stevens on the American Broadcasting Company, ABC television medical drama ''Grey's Anatomy'' from 2005 to 2010, a role that b ...
) about how life's biggest moments often come unexpectedly, shaping one's lives in profound ways. Izzie is excited about the wedding of
Meredith Grey Meredith Grey M.D., F.A.C.S., (born 1977 or 1978) is a fictional and titular character from the medical drama television series ''Grey's Anatomy'', which airs on the American Broadcasting Company (ABC) in the United States. The character was c ...
(
Ellen Pompeo Ellen Kathleen Pompeo (; born November 10, 1969) is an American actress. One of the world's highest-paid actors since 2017, she has made multiple appearances on ''Forbes'' year-end lists. Her accolades include a Screen Actors Guild Award and a ...
) and
Derek Shepherd Derek Christopher Shepherd, often referred to as "McDreamy" for his "attractiveness", is a fictional surgeon from the ABC medical drama ''Grey's Anatomy'', portrayed by actor Patrick Dempsey. He made his first appearance in the series' pilot ep ...
(
Patrick Dempsey Patrick Galen Dempsey (born January 13, 1966) is an American actor and racing driver best known for playing neurosurgeon Derek Shepherd in ''Grey's Anatomy'' (2005–15; 2020–21). He is also known for his leading man romantic film roles, such ...
), which she prepared and will take place at the end of the day. Stevens, who has been diagnosed with stage IV metastatic cancer in her brain and liver, has just undergone a surgery to remove a tumor. She however has hallucinations of Denny Duquette (
Jeffrey Dean Morgan Jeffrey Dean Morgan (born April 22, 1966) is an American actor. He is best known for playing the character Negan in the AMC horror drama series '' The Walking Dead'' (2016–2022) and its spin-off '' The Walking Dead: Dead City'' (2023–present ...
), her former deceased fiancé, which she knows means she has another tumor. Meanwhile,
Cristina Yang Cristina Yang, Doctor of Medicine, M.D., Doctor of Philosophy, Ph.D., F.A.C.S. is a fictional character from the medical drama television series ''Grey's Anatomy'', which has aired for 20 seasons on the American Broadcasting Company (ABC) in the ...
(
Sandra Oh Sandra Miju Oh (born July 20, 1971) is a Canadian and American actress. She is known for her starring roles as Rita Wu in ''Arliss (TV series), Arliss'' (1996–2002), Cristina Yang in ''Grey's Anatomy'' (2005–14), and Eve Polastri in ''Kill ...
) and Owen Hunt (
Kevin McKidd Kevin McKidd (born 9 August 1973) is a Scottish actor and television director best known as Dr. Owen Hunt in ''Grey's Anatomy'' and Tommy Mackenzie in Danny Boyle's '' Trainspotting'' (1996). McKidd played Colin in the 2008 film Made of Hono ...
)'s relationship is still strained after Hunt's
PTSD Post-traumatic stress disorder (PTSD) is a mental disorder that develops from experiencing a traumatic event, such as sexual assault, domestic violence, child abuse, warfare and its associated traumas, natural disaster, traffic collision, ...
caused him to strangle Yang while they were sleeping. Callie Torres (
Sara Ramirez Sara Elena Ramírez Vargas (; born August 31, 1975) is an American actor. Born in Mazatlán, Mazatlán, Sinaloa, Ramírez moved from Mexico to the United States at eight years old, eventually graduating with a fine arts degree from the Juillia ...
) who has financial difficulties takes extra shifts. A group of college students who were going to their graduation arrives in the hospital following a car accident. Arizona Robbins ( Jessica Capshaw) tries to know what went wrong the previous night during her date with Callie but she avoids the subject. When Miranda Bailey ( Chandra Wilson) and Derek cannot find any tumor in Izzie's brain from the
MRI Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and rad ...
, they decide to map her brain while she hallucinates and they discover an inoperable tumor. Afterwards, Bailey has an idea and shares it with Derek. Meredith receives her first solo surgery as wedding gift from Derek. The colon surgery is overseen by Richard Webber ( James Pickens, Jr.), which turns out to be successful. Derek tells her Bailey's idea. In the meantime, George O'Malley ( T. R. Knight) is depressed when all his patients from the car accident die until Hunt tells him one case where he helped has survived. Later on, Callie eventually confesses to Arizona why the date didn't go well: they went to an expensive restaurant that she couldn't afford because she has been disowned by her father and now she is broke. Arizona tells her they will stay in to eat and they reconcile. Meredith tells Bailey and Derek's idea to Izzie: they give her their wedding. Yang becomes the maid of honor and Meredith serves as Alex's best man. Back at the hospital, Izzie is sad about her hair loss but Alex tells her she doesn't need it to be beautiful. The episode concludes with Izzie having shaved her head and telling Denny to leave as she wants to be alone with her husband.


Production

The episode, written by
Shonda Rhimes Shonda Lynn Rhimes (born January 13, 1970) is an American television producer and screenwriter, and founder of the production company Shondaland. Inducted into the Television Hall of Fame and NAB Broadcasting Hall of Fame, Rhimes became known ...
and directed by
Rob Corn Robert L. Corn (born August 12, 1955) is an American television producer and director best known for Girls Club (TV series), Girls Club (2002), The District (2000), The Resident (TV series), The Resident (2018), Grey's Anatomy (2005), Chicago Hop ...
, was filmed in Los Angeles in March 2009. Featured music included Matthew Mayfield's "First In Line", Au Revoir Simone, "Another Likely Story" and
Ingrid Michaelson Ingrid Ellen Michaelson (born December 8, 1979) is an American singer-songwriter. She is best known for her 2006 single "The Way I Am (Ingrid Michaelson song), The Way I Am" and her 2014 single "Girls Chase Boys", both of which achieved success ...
's "Turn To Stone". Izzie's Amsale dress, constituted of a long tulle skirt with an elaborate crystal-embroidered bodice, was designed by Kenneth Pool. The bridesmaids dresses were also from Amsale.
Jeffrey Dean Morgan Jeffrey Dean Morgan (born April 22, 1966) is an American actor. He is best known for playing the character Negan in the AMC horror drama series '' The Walking Dead'' (2016–2022) and its spin-off '' The Walking Dead: Dead City'' (2023–present ...
returned as Denny Duquette for a final appearance in the series. Rhimes noted that his return, unlike previous ones, were as Death and caused him to wear black clothes and speak sparingly. Rhimes felt that the episode showed well Meredith's evolution throughout the show from a "dark and twisty girl" to a "happy woman". "She is the thing her mother wished for her. She is extraordinary. Because, to get past the crap of your past? To move on? To let the past go and change? That is extraordinary. To love? Without fear? Without screwing it up? That is extraordinary. It makes me happy to see her happy." Rhimes said that Karev also had grown up, which was noticeable in this episode: "Look at him. Standing at the altar and saying those vows like a man. (...) He's become a man who can step up. And I love him for it." To promote the episode, a special website for Meredith and Derek's wedding was created, supposedly created and updated by Izzie. The website provided details on the event and an invitation to RSVP. Rhimes wanted it to "feel like a real wedding website", even though it was for fictional characters. She came up with this idea during the shooting.


Reception

"What a Difference a Day Makes" was originally broadcast on May 7, 2009 in the United States on the
American Broadcasting Company The American Broadcasting Company (ABC) is an American Commercial broadcasting, commercial broadcast Television broadcaster, television and radio Radio network, network that serves as the flagship property of the Disney Entertainment division ...
(ABC). The episode was watched by a total of 15.326 million people, a slight increase from the previous episode "No Good at Saying Sorry", which garnered 13.485 million viewers. In terms of viewership, the episode ranked #1 in its time-slot, beating out
CBS CBS Broadcasting Inc., commonly shortened to CBS (an abbreviation of its original name, Columbia Broadcasting System), is an American commercial broadcast television and radio network serving as the flagship property of the CBS Entertainme ...
's '' CSI: Crime Scene Investigation''. "What a Difference a Day Makes" scored a 5.3/14 Nielsen rating/share in the adults among the 18–49 demographic.
Alan Sepinwall Alan Sepinwall (born October 19, 1973) is an American television reviewer and writer. He spent 14 years as a columnist with ''The Star-Ledger'' in Newark until leaving the newspaper in 2010 to work for the entertainment news website HitFix. He ...
of the ''
Star-Ledger ''The Star-Ledger'' was the largest circulation newspaper in New Jersey. It is based in Newark, New Jersey. The newspaper ceased print publication on February 2, 2025, but continues to publish a digital edition. In 2007, ''The Star-Ledger''s ...
'' gave a positive review of the episode: "For an episode that was so Izzie-centric, 'What a Difference a Day Makes' worked surprisingly well for me." Even though he pointed out Chandra Wilson as "the best actor in the ensemble", Sepinwall liked Justin Chambers' acting, "because of how far Karev has come, Chambers' big moments always feel more surprising, and powerful." He also appreciated "all the action in the pit." ''
Entertainment Weekly ''Entertainment Weekly'' (sometimes abbreviated as ''EW'') is an American online magazine, digital-only entertainment magazine based in New York City, published by Dotdash Meredith, that covers film, television, music, Broadway theatre, books, ...
'' listed Alex's speech to Izzie in their "25 Great 'I Love You's". The ''
Los Angeles Times The ''Los Angeles Times'' is an American Newspaper#Daily, daily newspaper that began publishing in Los Angeles, California, in 1881. Based in the Greater Los Angeles city of El Segundo, California, El Segundo since 2018, it is the List of new ...
'' writer Shawna Malcolm wasn't shocked that Izzie and Alex married instead of Meredith and Derek as she had already elaborated that hypothesis weeks prior to the episode's broadcast. She underlined Heigl and Chambers' performances, saying: "it was next to impossible not to get swept up in the moment, what with Heigl and Chambers getting all teary and acting the hell out of the thing." ''
Zap2it Zap2it was a website and digital media company that provided television program listings information for areas of the United States and Canada. Founded in 2000 by Tribune Media Services, the site has been owned by Nexstar Media Group since 201 ...
'''s Lisa Todorovich wrote: "Oh, Shonda Rhimes, you minx! You get us all excited for the long-awaited marital-union between Meredith and Derek, and you pull a great big bait-and-switch with Izzie and Alex. Congratulations on the very nice-looking bridesmaids' dresses." She described the wedding as "great" and George "brilliant for helping Izzie walk down the aisle". She also praised Callie "who handled the ER like a champ". Todorovich's colleague Ghosh Korbi suspected a week before the episode aired that it would center on Izzie and Alex." Dustin Christian of ''CinemaBlend'' said the wedding was "actually much better than the wedding we were led to expect." However, he thought that everything happening before the last 15 minutes was not interesting. Though he likes Callie and Arizona as a couple, he deemed their storyline "ridiculous". '' BuzzSugar'' summarized the episode as one that "has all the elements of a classic". The reviewer wrote that the wedding made him cry "despite lots of lapses in logic. It's not my favorite ''Grey's'' of the season, but if a measure of a good episode is whether I was a weepy mess by the end, then "What a Difference a Day Makes" is certainly good." He shared Malcolm's point of view that Izzie/Alex wedding twist was not surprising and concerning other minor plotlines, he called Arizona a "pest". Izzie was featured in ''
InStyle ''InStyle'' is an American monthly women's fashion magazine founded in 1994. It was published in the United States by Dotdash Meredith, and started originally as a brand extension of ''People (magazine), People'' before carving out its own ide ...
'' Most Memorable TV Brides. Meeta Agrawal of ''Entertainment Weekly'' said "while Izzie's trip down the aisle was the stuff of fairy-tales, her Amsale gown — with its unflattering drop waist and glitter-pen doodling — didn't quite live up to the fantasy".


References


External links


"What a Difference a Day Makes"
at ABC.com * {{Grey's Anatomy episodes, 5 Grey's Anatomy season 5 episodes 2009 American television episodes Television episodes about weddings