Wacław Mayzel (12 September 1847 – 19 April 1916) was a Polish
histologist and the first person to describe
mitosis
Mitosis () is a part of the cell cycle in eukaryote, eukaryotic cells in which replicated chromosomes are separated into two new Cell nucleus, nuclei. Cell division by mitosis is an equational division which gives rise to genetically identic ...
. He was also involved in popularizing evolutionary thinking by translating Darwin's ''On the Origin of Specie''s into Polish in 1873.
Biography
Wacław Mayzel was born on 12 September 1847 to Józef and Rozalia (Minheymer) Mayzel, in Kunów, Poland. Having graduated
St Ann's secondary school in
Kraków
, officially the Royal Capital City of Kraków, is the List of cities and towns in Poland, second-largest and one of the oldest cities in Poland. Situated on the Vistula River in Lesser Poland Voivodeship, the city has a population of 804,237 ...
in 1865, he enrolled at the Faculty of Medicine in the Warsaw General School. Five years later, Mayzel earned a doctorate in the field. During his time as a student, and while working at
Henryk Fryderyk Hoyer's Institute of Histology and Physiology, he wrote a paper titled ''Poszukiwania nad powstawaniem ropy'' (''Exploring the formation of
pus
Pus is an exudate, typically white-yellow, yellow, or yellow-brown, formed at the site of inflammation during infections, regardless of cause. An accumulation of pus in an enclosed tissue space is known as an abscess, whereas a visible collect ...
''), critically acclaimed by his faculty. In it, Mayzel discusses
Cohnheim's claims that during inflammation,
leukocytes
White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign entities. White blood cells are genera ...
exit blood vessels and take part in the formation of pus.
After receiving a diploma ''cum eximia laude'', Mayzel took up a position of a lab assistant in Hoyer's Histology and Embryology faculty, instructing students in microscope usage, and conducting his own research. While observing
epithelium
Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis, the outermost layer of the skin. Epithelial ( mesothelial) tissues line the outer surfaces of man ...
regeneration, he noticed that
nuclei of some of the newly formed cells feature unknown to him grains and fibers. He then, in 1874, informed the Warsaw Medical Association about his research so as to be credited in case an important discovery is made.
Eduard Strasburger
Eduard Adolf Strasburger (1 February 1844 – 18 May 1912) was a Polish- German professor and one of the most famous botanists of the 19th century. He discovered mitosis in plants.
Life
Eduard Strasburger was born in Warsaw, Congress Poland, t ...
and
Otto Bütschli
Johann Adam Otto Bütschli (3 May 1848 – 2 February 1920) was a German zoologist and professor at the University of Heidelberg. He specialized in invertebrates and insect development. Many of the groups of protists were first recognized by him.
...
's work, published the following year, convinced Mayzel that his observations are related to the division of the nucleus, and so he presented them in a paper titled ''Ueber eigenthümliche Vorgänge bei der Theilung der Kerne in Epithelialzellen'' or ''O szczególnych zjawiskach przy dzieleniu się jąder w komórkach nabłonkowych'' (''On peculiar occurrences during the division of nuclei in epithelium cells'').
In the following years, Mayzel continued his research and published more papers, sometimes illustrating them on his own. He made observations on mitosis in living cells, including the order of changes that happen during the division, noticed an analogy in impregnation and early development of animal and plant cells, and spoke against the idea of
karyolysis. He presented his research to a wider public during various medical conferences in
Kraków
, officially the Royal Capital City of Kraków, is the List of cities and towns in Poland, second-largest and one of the oldest cities in Poland. Situated on the Vistula River in Lesser Poland Voivodeship, the city has a population of 804,237 ...
,
Berlin
Berlin ( ; ) is the Capital of Germany, capital and largest city of Germany, by both area and List of cities in Germany by population, population. With 3.7 million inhabitants, it has the List of cities in the European Union by population withi ...
,
Prague
Prague ( ; ) is the capital and List of cities and towns in the Czech Republic, largest city of the Czech Republic and the historical capital of Bohemia. Prague, located on the Vltava River, has a population of about 1.4 million, while its P ...
,
Paris
Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of ci ...
,
London
London is the Capital city, capital and List of urban areas in the United Kingdom, largest city of both England and the United Kingdom, with a population of in . London metropolitan area, Its wider metropolitan area is the largest in Wester ...
,
Rome
Rome (Italian language, Italian and , ) is the capital city and most populated (municipality) of Italy. It is also the administrative centre of the Lazio Regions of Italy, region and of the Metropolitan City of Rome. A special named with 2, ...
, and
Madrid
Madrid ( ; ) is the capital and List of largest cities in Spain, most populous municipality of Spain. It has almost 3.5 million inhabitants and a Madrid metropolitan area, metropolitan area population of approximately 7 million. It i ...
.
Apart from the work related to mitosis, Mayzel took up educational and humanitarian activities. As a hygienist and bacteriologist, he helped set up waterworks and a sewerage system in
Warsaw
Warsaw, officially the Capital City of Warsaw, is the capital and List of cities and towns in Poland, largest city of Poland. The metropolis stands on the Vistula, River Vistula in east-central Poland. Its population is officially estimated at ...
, and published numerous papers on microscopic water analysis. Despite not centering his career on therapeutics, Mayzel showed interest in parasitology, tuberculosis research, and medical analysis, and temporarily worked in a clinic in Warsaw. Among his interests was also urology, particularly urine analysis; in 1894, during a medical conference in Rome, he presented his own method of detecting
uric acid
Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the Chemical formula, formula C5H4N4O3. It forms ions and salts known as urates and acid urates, such as ammonium acid urate. Uric acid is a product of the meta ...
in urine. Mayzel translated or helped translate about a dozen works into the
Polish language
Polish (, , or simply , ) is a West Slavic languages, West Slavic language of the Lechitic languages, Lechitic subgroup, within the Indo-European languages, Indo-European language family, and is written in the Latin script. It is primarily spo ...
, including
Charles Darwin
Charles Robert Darwin ( ; 12 February 1809 – 19 April 1882) was an English Natural history#Before 1900, naturalist, geologist, and biologist, widely known for his contributions to evolutionary biology. His proposition that all speci ...
's ''
On the Origin of Species
''On the Origin of Species'' (or, more completely, ''On the Origin of Species by Means of Natural Selection, or the Preservation of Favoured Races in the Struggle for Life'')The book's full original title was ''On the Origin of Species by M ...
''.
Personal life
Wacław Mayzel was married to Bronisława Mayzel (Kleszczyńska), and had a daughter Zofia Guźkowska (Mayzel).
Selected works
*
Poszukiwania nad powstawaniem ropy' (Klinika, 1869)
*''O powstawaniu gatunków drogą naturalnego doboru czyli O utrzymywaniu się doskonalszych ras istot organicznych w walce o byt'
Part 1Part 2
(1873)
*''Ueber eigenthümliche Vorgänge bei der Theilung der Kerne in Epithelialzellen'' (Zentralblatt für die Medizinischen Wissenschaften, 1875)
*''O szczególnych zjawiskach przy dzieleniu się jąder w komórkach nabłonkowych'' (Medycyna, 1875)
*''Przyczynek do sprawy dzielenia się jąder komórkowych'' (Gazeta Lekarska, 1876)
*''Dalszy przyczynek do sprawy dzielenia się jąder komórkowych'' (Gazeta Lekarska, 1877)
*''O pierwszych zmianach w jajku zapłodnionem i o podziale komórek'' (Pamphlet Towarzystwa Lekarskiego Warszawskiego, 1878)
*''O zjawiskach przy segmentacji jajek robaków (Nematoda) i ślimaków'' (Gazeta Lekarska, 1879)
*''O karyomitozie'' (Księga pamiątkowa prof. Hoyera, 1884)
*''Wskazówki do rozbioru moczu'' (Rocznik Lekarski, 1890)
References
External links
Dr Wacław Mayzel : szkic biograficzny z powodu 35-lecia pracy zawodowej(Biography in Polish)
{{DEFAULTSORT:Mayzel, Wacław
University of Warsaw alumni
Scientists from Congress Poland
Polish microbiologists
Polish public health doctors
1847 births
1916 deaths
Burials at Powązki Cemetery
People from Ostrowiec County
Histologists
Polish translators
19th-century Polish translators