Valentín Fuster Carulla, 1st Marquess of Fuster (born January 20, 1943) is a Spanish

cardiologist Cardiology () is the study of the heart. Cardiology is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery di ...

and

aristocrat The aristocracy (''from Greek'' ''ἀριστοκρατία'' ''aristokratía'', "rule of the best"; ''Latin: aristocratia'') is historically associated with a "hereditary" or a "ruling" social class. In many states, the aristocracy included the ...

. He was

editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The editor-in-chief heads all departments of the organization and is held accoun ...

of the ''

Journal of the American College of Cardiology The ''Journal of the American College of Cardiology'' is a peer-reviewed medical journal covering all aspects of cardiovascular disease, including original clinical studies, translational investigations with clear clinical relevance, state-of-the-a ...

'' (JACC), past President of the

American Heart Association The American Heart Association (AHA) is a nonprofit organization in the United States that funds cardiovascular medical research, educates consumers on healthy living and fosters appropriate Heart, cardiac care in an effort to reduce disability ...

, past President of the World Heart Federation, and has been a member of the US

National Academy of Medicine The National Academy of Medicine (NAM), known as the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Engineerin ...

and Member of the European Horizon 2020 Scientific Panel of Health. In 2016 he co-chaired, with Jendayi Frazer, the Advisory Committee on ''The Role of the United States on Global Health''. Fuster serves as President of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital, and Director of the Zena and Michael A. Wiener Cardiovascular Institute, the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, Richard Gorlin, MD/Heart Research Foundation, and Professor at

Icahn School of Medicine at Mount Sinai The Icahn School of Medicine at Mount Sinai (ISMMS or Mount Sinai), formerly the Mount Sinai School of Medicine, is a private medical school in New York City, New York, United States. The school is the academic teaching arm of the Mount Sina ...

."Doctor Profile", Mount Sinai Hospital
retrieved May 13, 2015 In October 2023 Mount Sinai Heart was renamed the Mount Sinai Fuster Heart Hospital. Deepak Bhatt succeeded Fuster in the role of director. He serves in

Madrid Madrid ( ; ) is the capital and List of largest cities in Spain, most populous municipality of Spain. It has almost 3.5 million inhabitants and a Madrid metropolitan area, metropolitan area population of approximately 7 million. It i ...

as the General Director of the National Centre for Cardiovascular Research (CNIC)Centro Nacional de Investigaciones Cardiovasculare and also chairs an international project, the SHE Foundation (Science for Health and Education). In 2014, King Juan Carlos I of Spain granted him the title of Marquis for his "outstanding and unceasing research efforts and his educational outreach work".

Life and career

Fuster was born in

Barcelona, Spain Barcelona ( ; ; ) is a city on the northeastern coast of Spain. It is the capital and largest city of the Autonomous communities of Spain, autonomous community of Catalonia, as well as the second-most populous municipality of Spain. With a pop ...

. He is the son of a

psychiatrist A psychiatrist is a physician who specializes in psychiatry. Psychiatrists are physicians who evaluate patients to determine whether their symptoms are the result of a physical illness, a combination of physical and mental ailments or strictly ...

, and his brother is a

neuroscientist A neuroscientist (or neurobiologist) is a scientist specializing in neuroscience that deals with the anatomy and function of neurons, Biological neural network, neural circuits, and glia, and their Behavior, behavioral, biological, and psycholo ...

. In Spain he competed in tennis at a national level. Pedro Farreras Valentí, the author of the widely used Spanish textbook ''Farreras-Rozman Internal Medicine'', encouraged Fuster to study cardiology. Fuster graduated first in his class with an MD from

University of Barcelona The University of Barcelona (official name in ; UB), formerly also known as Central University of Barcelona (), is a public research university located in the city of Barcelona, Catalonia, Spain. It was established in 1450. With 76,000 students, ...

in 1967. He completed an internship at the Hospital Clinic in Barcelona, then attended

University of Edinburgh Medical School The University of Edinburgh Medical School (also known as Edinburgh Medical School) is the medical school of the University of Edinburgh in Scotland and the United Kingdom and part of the University of Edinburgh College of Medicine and Veterinar ...

for a PhD on the role of

platelet Platelets or thrombocytes () are a part of blood whose function (along with the coagulation#Coagulation factors, coagulation factors) is to react to bleeding from blood vessel injury by clumping to form a thrombus, blood clot. Platelets have no ...

s in myocardial

infarction Infarction is tissue death (necrosis) due to Ischemia, inadequate blood supply to the affected area. It may be caused by Thrombosis, artery blockages, rupture, mechanical compression, or vasoconstriction. The resulting lesion is referred to as a ...

. Fuster served as a Research Fellow in Cardiology at the

Royal Infirmary of Edinburgh The Royal Infirmary of Edinburgh (RIE) was established in 1729, and is the oldest voluntary hospital in Scotland. The new buildings of 1879 were claimed to be the largest voluntary hospital in the United Kingdom, and later on, the Empire."In Com ...

from 1968 to 1971 After completing his PhD in 1971 from the

. Fuster spent several years at the

Mayo Clinic Mayo Clinic () is a Nonprofit organization, private American Academic health science centre, academic Medical centers in the United States, medical center focused on integrated health care, healthcare, Mayo Clinic College of Medicine and Science ...

, first as a resident and later as Professor of Medicine and Consultant in Cardiology. In 1981, he became head of cardiology at Mount Sinai School of Medicine. From 1991 to 1994, he was Mallinckrodt Professor of Medicine at

Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...

and Chief of Cardiology at the

Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is a teaching hospital located in the West End neighborhood of Boston, Massachusetts. It is the original and largest clinical education and research facility of Harvard Medical School/Harvar ...

. He returned to Mount Sinai in 1994 as Director of the Zena and Michael A. Wiener Cardiovascular Institute and in 2006 named the Director of Mount Sinai Heart, and in 2022, he was appointed president. Fuster serves as physician-in-chief and President of Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute and the Marie-Josee and Henry R. Kravis Center for Cardiovascular Health. He is also the Richard Gorlin, MD/Heart Research Foundation Professor at

. Fuster was the President of Science, and is now the General Director of the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) in

, (Spain)."Valentin Fuster Carulla", CNIC
retrieved March 12, 2013 Fuster was elected

at the ''

'' in 2014. Former positions include President of the American Heart Association, past president of the World Heart Federation, member of the Institute of Medicine of the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...

where he serves as Chair of the Committee on Preventing the Global Epidemic of Cardiovascular Disease, former member of the

National Heart, Lung, and Blood Institute The National Heart, Lung, and Blood Institute (NHLBI) is the third largest Institute of the National Institutes of Health, located in Bethesda, Maryland, United States. It is tasked with allocating about $3.6 billion in FY 2020 in tax revenue t ...

Advisory Council, and former Chairman of the Fellowship Training Directors Program of the

American College of Cardiology The American College of Cardiology (ACC), based in Washington, D.C., is a nonprofit medical association established in 1949. It bestows credentials upon cardiovascular specialists who meet its qualifications. Education is a core component of the ...

. He has thirty-four university Honorary Doctorates. According to Google Scholar, his peer-reviewed publications, as of 2020, have been cited 319,356. His h-index is 209 and i10-index is 1,206. He was the inspiration for a character on the Spanish version of ''

Sesame Street ''Sesame Street'' is an American educational television, educational children's television series that combines live-action, sketch comedy, animation, and puppetry. It is produced by Sesame Workshop (known as the Children's Television Worksh ...

'' named "Valentin Ruster" that educated children in healthier lifestyles through exercise and healthy diet.

Honors and awards

* 1992 Andreas Gruntzig Award of the International Society of Interventionalists (Paris)"Valentin Fuster Honored with Grand Prix Award", TheHeart
retrieved March 21, 2013 *1993 Distinguished Scientist Award, American College of Cardiology"Previous Years Distinguished Scientists", American Heart Association
retrieved March 21, 2013 * 1996 Principe de Asturias Award of Science and Technology, Fundacion Principe de Asturias, Oviedo, Spain * 2001 James B. Herrick Award, Council of Clinical Cardiology of the American Heart Association * 2005 2009 Distinguished Researcher Award, Interamerican Society of Cardiology * 2008 Polzer Prize, European Academy of Science and Arts * 2011 The LeFoulon Delalande Grand Prize, Institute of France, Paris, France * 2012 AHA Research Achievement Award, Los Angeles, CA"New York City scientist wins American Heart Association award for major additions to knowledge of artery disease process, treatments", American Heart Association
retrieved March 12, 2013 * 2014 Created Marquess of Fuster in the

Spanish nobility The Spanish nobility are people who possess a title of nobility confirmed by the Spanish Ministry of the Presidency, Justice and Relations with the Cortes, as well as those individuals appointed to one of Spain's three highest orders of knightho ...

by King

Juan Carlos I Juan Carlos I (; Juan Carlos Alfonso Víctor María de Borbón y Borbón-Dos Sicilias, born 5 January 1938) is a member of the Spanish royal family who reigned as King of Spain from 22 November 1975 until Abdication of Juan Carlos I, his abdic ...

. * 2017 Knight Grand Cross of the Civil Order of Alfonso X, the Wise *2020

Prince Mahidol Award The Prince Mahidol Award () is an annual award for outstanding achievements in medicine and public health worldwide. The award is given by the Prince Mahidol Award Foundation, which was founded by the Thai Royal Family in 1992. Prince Mahidol ...

in Medicine

Scientific investigator

Contributions in
translational medicine Translational medicine (often called translational science, of which it is a form) develops the clinical practice applications of the basic science aspects of the biomedical sciences; that is, it translates basic science to applied science in me ...

Chronology Fuster’s contributions for disease-to-health transitions encompass five phases leading to 4 guidelines Class I: 1980s: Demonstrating the role of platelets in coronary artery bypass graft ( CABG) occlusion based on imaging studies in dogs, and a pioneering trial of aspirin in human atherothrombotic disease. 1990s: Demonstrating that acute coronary events arise from small plaques, explaining their unpredictability, and developing diagnostic MRI imaging to characterize these “vulnerable plaques” and inhibiting post coronary angioplasty (PCI) fibrosis in pigs by

Rapamycin Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ rejection, organ transplant rejection, treat a rare lung disease called lymphang ...

, prompting the introduction of

drug-eluting stent A drug-eluting stent (DES) is a tube made of a mesh-like material used to treat atherosclerosis, narrowed arteries in medical procedures both mechanically (by providing a supporting scaffold inside the artery) and pharmacologically (by slowly ...

s (DES) to prevent PCI

restenosis Restenosis is the recurrence of stenosis, a narrowing of a blood vessel, leading to restricted blood flow. Restenosis usually pertains to an artery or other large blood vessel that has become narrowed, received treatment to clear the blockage, and ...

. 2000s: Following upon experience with CABG and DES for

revascularization In medical and surgical therapy, revascularization is the restoration of perfusion to a body part or organ that has had ischemia. It is typically accomplished by surgical means. Vascular bypass and angioplasty are the two primary means of r ...

in patients with diabetes and multivessel coronary disease changing American and European practice guidelines. 2010s: To improve poor medication adherence, as observed in FREEDOM and other studies, a fixed-dose polypill (aspirin,

ramipril Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It can also be used as a preventative medication in patients over 55 y ...

and

statin Statins (or HMG-CoA reductase inhibitors) are a class of medications that lower cholesterol. They are prescribed typically to people who are at high risk of cardiovascular disease. Low-density lipoprotein (LDL) carriers of cholesterol play ...

) was developed, the first approved for secondary prevention in 40 countries. 2015 to present (2021): Established the predictive value of identifying atherosclerotic burden by noninvasive imaging (3D ultrasound, EBCT, PET, MRI) and genetics in 4 studies of 11,000 asymptomatic adults. Thus, in collaboration with the producers of Sesame Street television, conducted randomized studies of 3,000 children, 2,000 parents and 300 teachers in

Colombia Colombia, officially the Republic of Colombia, is a country primarily located in South America with Insular region of Colombia, insular regions in North America. The Colombian mainland is bordered by the Caribbean Sea to the north, Venezuel ...

Spain Spain, or the Kingdom of Spain, is a country in Southern Europe, Southern and Western Europe with territories in North Africa. Featuring the Punta de Tarifa, southernmost point of continental Europe, it is the largest country in Southern Eur ...

and

Harlem Harlem is a neighborhood in Upper Manhattan, New York City. It is bounded roughly by the Hudson River on the west; the Harlem River and 155th Street on the north; Fifth Avenue on the east; and Central Park North on the south. The greater ...

(New York). Sixty hours of health education over six months showed a significant impact on knowledge, attitude, habits and weight within three years.

Books

Author

*Hurst's the ''Heart Manual of Cardiology'', 12th Edition by Robert O'Rourke, Richard Walsh and Valentin Fuster (Jan 27, 2009) *''The Heart Manual: My Scientific Advice for Eating Better, Feeling Better, and Living a Stress-Free Life Now'' by Valentin Fuster (Feb 2, 2010) *The ''AHA Guidelines and Scientific Statements Handbook'' (Fuster, The AHA Guidelines And Scientific Statements Handbook) by Valentin Fuster (Jan 6, 2009) *''Atherothrombosis and Coronary Artery Disease'' by Valentin Fuster, Eric J. Topol and Elizabeth G. Nabel (Nov 8, 2004) *Platelets in Thrombotic and Non-Thrombotic Disorders Pathophysiology, Pharmacology and Therapeutics Paolo Gresele, Clive P. Page, Valentin Fuster, Jos Vermylen Hardback () *Thrombosis in Cardiovascular Disorders ardcoverValentin Fuster (Author), Marc Verstraete (Author) *Update on Coronary Risk Factors, An Issue of Medical Clinics of North America ardcoverValentin Fuster, MD, PhD (Author), and Jagat Narula *La Ciencia de la Salud: Mis consejos para una vida sana (Spanish Edition) by Valentin Fuster (Dec 26, 2007) *Cardiovascular Thrombosis: Thrombocardiology and Thromboneurology ardcoverMarc Verstraete (Author), Valentin Fuster (Author), Fuster (Author) *La ciencia y la vida/ Science And Life (Spanish Edition) aperbackValentin Fuster (Author), Jose Luis Sampedro (Author) *[Cardiovascular Magnetic Resonance: Established and Emerging Applications ardcoverAlbert Lardo (Author), Zahi Fayad (Author), Nicolas Chronos (Author), Valentin Fuster (Author) *La pequeña ciencia de la salud erfect PaperbackValentin Fuster (Author) *Monstruos supersanos erfect PaperbackValentin Fuster (Author) *La cocina de la salud by Valentín Fuster / Ferran Adrià / Josep Corbella (2010) *La vostra salute mi sta a cuore erfect PaperbackJosep Corbella Valentín Fuster *La buona cucina della salute. La ricetta di un famoso chef e di un grande medico per vivere bene senza rinunce erfect PaperbackValentin Fuster, Josep Corbella Ferran Adrià (Author) *El Círculo de la motivación laneta de LibrosValentín Fuster con la colaboracíon de Emma Reverter

Editor

*The Vulnerable Atherosclerotic Plaque: Understanding, Identification and Modification ardcoverValentin Fuster (Editor) *Evolving Challenges in Promoting Cardiovascular Health by Annals of the New York Academy of Sciences Editorial Staff, Valentin Fuster (Editor) May 2012, Paperback *Assessing and Modifying the Vulnerable Atherosclerotic Plaque by Valentin Fuster (Editor) with William Insull Jr., MD June 2002, Hardcover *Oxidative Stress and Cardiac Failure by Marrick Kukin (Editor), Valentin Fuster (Editor) October 2002, Hardcover *Platelets in Hematologic and Cardiovascular Disorders: A Clinical Handbook ardcoverPaolo Gresele (Editor), Valentin Fuster (Editor), Jose A. Lopez (Editor), Clive P. Page (Editor), Jos Vermylen (Editor) *Promoting Cardiovascular Health in the Developing World: A Critical Challenge to Achieve Global Health] aperbackCommittee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries (Author), Institute of Medicine (Author), Valentin Fuster (Editor), Bridget B. Kelly (Editor) *Syndromes of Atherosclerosis: Correlations of Clinical Imaging and Pathology ardcoverValentin Fuster (Editor) *Efficacy of Myocardial Infarction Therapy ardcoverValentin Fuster (Editor) *Editor-in-chief of ''Nature Reviews Cardiology'', April 2009

References

External links

Mount Sinai Hospital homepageSHE Foundation
{{DEFAULTSORT:Fuster, Valentin Spanish emigrants to the United States Living people Harvard Medical School faculty Icahn School of Medicine at Mount Sinai faculty Physicians from Barcelona Recipients of the Civil Order of Alfonso X, the Wise Spanish cardiologists University of Barcelona alumni Alumni of the University of Edinburgh Fellows of the American College of Cardiology Members of the National Academy of Medicine 1943 births