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U.S. Route 52 (US 52) is a major
United States highway The United States Numbered Highway System (often called U.S. Routes or U.S. Highways) is an integrated network of roads and highways numbered within a nationwide grid in the contiguous United States. As the designation and numbering of these hi ...
in the
central United States The Central United States is sometimes conceived as between the Eastern and Western as part of a three-region model, roughly coincident with the U.S. Census' definition of the Midwestern United States plus the western and central portions of ...
that extends from the northern to southeastern region of the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
. Contrary to most other even-numbered U.S. Highways, US 52 primarily follows a northwest–southeast route, and is signed north–south or east–west depending on the local orientation of the route. The highway's northwestern terminus is in
Portal, North Dakota Portal is a city in Burke County, North Dakota, United States. The population was 125 at the 2020 census. Portal was founded in 1893. Portal sits along the Canada–United States border and is a major port of entry for road and rail traffic. No ...
at the
Canadian Canadians (french: Canadiens) are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of ...
border, where it continues as
Saskatchewan Highway 39 Highway 39 is a provincial, paved, undivided highway located in the southern portion of the Canadian province of Saskatchewan connecting North Portal and Moose Jaw in the north. This is a primary Saskatchewan highway maintained by the provincia ...
. Its southeastern terminus is in
Charleston, South Carolina Charleston is the largest city in the U.S. state of South Carolina, the county seat of Charleston County, and the principal city in the Charleston–North Charleston metropolitan area. The city lies just south of the geographical midpoint o ...
, at Number 2 Meeting Street and
White Point Garden White Point Garden is a 5.7 acre public park located in peninsular Charleston, South Carolina, at the tip of the peninsula. It is the southern terminus for The Battery (Charleston), the Battery, a defensive seawall and promenade. It is bounded ...
along the Charleston Harbor.


Route description

, - , ND , , - , MN , , - , IA , , - , IL , , - , IN , , - , OH , , - , WV/KY , , - , VA , , - , NC , , - , SC , , - , Total ,


North Dakota

In
North Dakota North Dakota () is a U.S. state in the Upper Midwest, named after the Native Americans in the United States, indigenous Dakota people, Dakota Sioux. North Dakota is bordered by the Canadian provinces of Saskatchewan and Manitoba to the north a ...
, US 52 continues from Highway 39 from the
Canadian border Canadians (french: Canadiens) are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of ...
at
North Portal, Saskatchewan North is one of the four compass points or cardinal directions. It is the opposite of south and is perpendicular to east and west. ''North'' is a noun, adjective, or adverb indicating direction or geography. Etymology The word ''north'' is ...
, and
Portal, North Dakota Portal is a city in Burke County, North Dakota, United States. The population was 125 at the 2020 census. Portal was founded in 1893. Portal sits along the Canada–United States border and is a major port of entry for road and rail traffic. No ...
, to the Red River in Fargo, a distance of . US 52 is co-signed with US 2 near
Minot Minot ( ) is a city in and the county seat of Ward County, North Dakota, Ward County, North Dakota, United States, in the state's north-central region. It is most widely known for the Minot Air Force Base, Air Force base approximately north of ...
, where it also intersects with US 83. US 52 is also co-signed with US 281 for between Jamestown and Carrington. US 52 is concurrent with
Interstate 94 Interstate 94 (I-94) is an east–west Interstate Highway connecting the Great Lakes and northern Great Plains regions of the United States. Its western terminus is just east of Billings, Montana, at a junction with I-90; its eastern ter ...
(I-94) between Jamestown and the
Minnesota Minnesota () is a state in the upper midwestern region of the United States. It is the 12th largest U.S. state in area and the 22nd most populous, with over 5.75 million residents. Minnesota is home to western prairies, now given over to ...
state line, co-signed between Jamestown and Fargo; however, all of the interchanges for the Fargo– West Fargo portion of the route are
unsigned Unsigned can refer to: * An unsigned artist is a musical artist or group not attached or signed to a record label ** Unsigned Music Awards, ceremony noting achievements of unsigned artists ** Unsigned band web, online community * Similarly, the c ...
.


Minnesota

In the state of
Minnesota Minnesota () is a state in the upper midwestern region of the United States. It is the 12th largest U.S. state in area and the 22nd most populous, with over 5.75 million residents. Minnesota is home to western prairies, now given over to ...
, US 52 enters the state with I-94 at Moorhead and follows I-94 southeasterly all the way to the
Twin Cities Twin cities are a special case of two neighboring cities or urban centres that grow into a single conurbation – or narrowly separated urban areas – over time. There are no formal criteria, but twin cities are generally comparable in statu ...
. The portion of the highway which overlaps I-94 is unsigned. From downtown St. Paul, US 52 continues on its own southeast over the
Lafayette Bridge The Lafayette Bridge is a bridge carrying U.S. Route 52 across the Mississippi River in downtown Saint Paul, Minnesota. At this point, US 52 is on the Lafayette Freeway. The bridge spans across railroad yards north of the Mississippi, the river i ...
in St. Paul, continuing as a four-lane road to
Rochester Rochester may refer to: Places Australia * Rochester, Victoria Canada * Rochester, Alberta United Kingdom *Rochester, Kent ** City of Rochester-upon-Medway (1982–1998), district council area ** History of Rochester, Kent ** HM Prison ...
and the Iowa state line. The
Minnesota Department of Transportation The Minnesota Department of Transportation (MnDOT, ) oversees transportation by all modes including land, water, air, rail, walking and bicycling in the U.S. state of Minnesota. The cabinet-level agency is responsible for maintaining the state' ...
has a long-term goal of making US 52 a freeway with limited-access interchanges between St. Paul and
I-90 Interstate 90 (I-90) is an east–west transcontinental freeway and the longest Interstate Highway in the United States at . It begins in Seattle, Washington, and travels through the Pacific Northwest, Mountain West, Great Plains, Midwest, and ...
south of Rochester. South from I-94 in St. Paul there is a freeway segment to just south of Concord Boulevard in
Inver Grove Heights Inver Grove Heights is a city in Dakota County, Minnesota, United States. The population was 35,801 at the 2020 census. The city was formed on March 9, 1965, with the merger of the village of Inver Grove and Inver Grove Township. It is one of 1 ...
. The portion of the highway between Inver Grove Heights and Pine Island is built to
expressway Expressway may refer to: * Controlled-access highway, the highest-grade type of highway with access ramps, lane markings, etc., for high-speed traffic. * Limited-access road, a lower grade of highway or arterial road. *Expressway, the fictional s ...
standards. Another freeway segment begins from Pine Island, through Rochester reaching its largest single capacity in Minnesota through Rochester as a six- to eight-lane freeway, toward I-90 where it converts to a rural two-lane highway. The highway then proceeds to the Iowa state line.


Iowa

US 52 enters
Iowa Iowa () is a state in the Midwestern region of the United States, bordered by the Mississippi River to the east and the Missouri River and Big Sioux River to the west. It is bordered by six states: Wisconsin to the northeast, Illinois to the ...
north of the unincorporated community of
Burr Oak ''Quercus macrocarpa'', the bur oak or burr oak, is a species of oak tree native to eastern North America. It is in the white oak section, ''Quercus'' sect. ''Quercus'', and is also called mossycup oak, mossycup white oak, blue oak, or scrub oa ...
. It passes by Luther College on the west side of Decorah. At Calmar the road turns to a southwest–northeast orientation. It joins with US 18 just to the west of
Postville Postville is a village in Allamakee and Clayton counties in the U.S. state of Iowa. It lies near the junction of four counties and at the intersection of U.S. Routes 18 and 52 and Iowa Highway 51, with airport facilities in the neighboring co ...
. The two highways overlap until a point east of the unincorporated community of Froelich. US 52 roughly parallels the
Mississippi River The Mississippi River is the second-longest river and chief river of the second-largest drainage system in North America, second only to the Hudson Bay drainage system. From its traditional source of Lake Itasca in northern Minnesota, it f ...
for the rest of its path through Iowa to
Dyersville Dyersville is a city in eastern Delaware County and western Dubuque County in the U.S. state of Iowa. It is part of the Dubuque, Iowa, Metropolitan Statistical Area. The population was 4,477 at the time of the 2020 census, up from 4,035 in 200 ...
, where it intersects and joins US 20 and turns eastward towards
Dubuque Dubuque (, ) is the county seat of Dubuque County, Iowa, United States, located along the Mississippi River. At the time of the 2020 census, the population of Dubuque was 59,667. The city lies at the junction of Iowa, Illinois, and Wisconsin, a r ...
. West of Dubuque, US 52 merges south onto the
Southwest Arterial U.S. Highway 52 (US 52) is a United States Numbered Highway in northeast Iowa. The route begins at the Dale Gardner Veterans Memorial Bridge over the Mississippi River between Sabula and Savanna, Illinois. From Sabula, it heads north along th ...
, a four-lane expressway directing traffic around the southern edge of the city. US 52 heads southeast to a junction with US 61 and US 151. All three routes travel northbound (even US 52, which is signed as southbound) as an expressway, until US 52 departs in
Key West Key West ( es, Cayo Hueso) is an island in the Straits of Florida, within the U.S. state of Florida. Together with all or parts of the separate islands of Dredgers Key, Fleming Key, Sunset Key, and the northern part of Stock Island, it cons ...
to remain close to the Mississippi River. After passing through a hilly and scenic region, including the small river city of
Bellevue Bellevue means "beautiful view" in French. It may refer to: Placenames Australia * Bellevue, Western Australia * Bellevue Hill, New South Wales * Bellevue, Queensland * Bellevue, Glebe, an historic house in Sydney, New South Wales Canada ...
, the highway turns to an east–west orientation near Sabula at the junction of
Iowa Highway 64 Iowa Highway 64 (Iowa 64) is a state highway that runs through two counties in east central Iowa. It begins at an interchange with U.S. Route 151 (US 151) in Anamosa and ends at the Dale Gardner Veterans Memorial Bridge over the Miss ...
and the northern terminus of US 67. In Sabula, the highway becomes a wrong-way road; northbound traffic travels south, and vice versa, from Sabula to the
Dale Gardner Veterans Memorial Bridge The Dale Gardner Veterans Memorial Bridge, often referred to as the New Savanna-Sabula Bridge, or by the same name as its predecessor, the Savanna-Sabula Bridge, is a steel tied-arch that carries U.S. Route 52 (US 52) across the Mississippi ...
, where US 52 crosses over the
Mississippi River The Mississippi River is the second-longest river and chief river of the second-largest drainage system in North America, second only to the Hudson Bay drainage system. From its traditional source of Lake Itasca in northern Minnesota, it f ...
into
Illinois Illinois ( ) is a U.S. state, state in the Midwestern United States, Midwestern United States. Its largest metropolitan areas include the Chicago metropolitan area, and the Metro East section, of Greater St. Louis. Other smaller metropolita ...
. North of Dubuque, US 52 was formerly routed onto a narrow and winding road, concurrently with Iowa Highway 3. While scenic, the road has been the scene of numerous accidents over the years owing to this nature. Between 1964 and 1967, this segment of the route was designated Alternate US 52 and US 52 was rerouted south from Luxemburg to Dyersville along Iowa Highway 136, and east from Dyersville to Dubuque along US 20; however in 1967, US 52 was restored to the Iowa Highway 3 alignment. After the completion of the Southwest Arterial in 2020, a similar change took place as US 52 was once again removed from the Iowa Highway 3 alignment and again routed from Luxemburg to Dyersville to Dubuque, then onto the Southwest Arterial, to US 61/US 151, finally reaching its former routing at Key West. The majority of US 52 in Iowa is located within the unglaciated
Driftless Area The Driftless Area, a topographical and cultural region in the American Midwest, comprises southwestern Wisconsin, southeastern Minnesota, northeastern Iowa, and the extreme northwestern corner of Illinois. Never covered by ice during the last ...
.


Illinois

In
Illinois Illinois ( ) is a U.S. state, state in the Midwestern United States, Midwestern United States. Its largest metropolitan areas include the Chicago metropolitan area, and the Metro East section, of Greater St. Louis. Other smaller metropolita ...
, US 52 runs southeast from the
Dale Gardner Veterans Memorial Bridge The Dale Gardner Veterans Memorial Bridge, often referred to as the New Savanna-Sabula Bridge, or by the same name as its predecessor, the Savanna-Sabula Bridge, is a steel tied-arch that carries U.S. Route 52 (US 52) across the Mississippi ...
at the terminus of
Iowa Highway 64 Iowa Highway 64 (Iowa 64) is a state highway that runs through two counties in east central Iowa. It begins at an interchange with U.S. Route 151 (US 151) in Anamosa and ends at the Dale Gardner Veterans Memorial Bridge over the Mi ...
and Illinois Route 64 in
Savanna A savanna or savannah is a mixed woodland-grassland (i.e. grassy woodland) ecosystem characterised by the trees being sufficiently widely spaced so that the canopy does not close. The open canopy allows sufficient light to reach the ground to ...
, passing through the cities of Dixon,
Amboy Amboy may refer to: Places * Amboy, Córdoba, village in Calamuchita Department, Córdoba province, Argentina United States * Amboy Crater, feature in Mojave National Preserve, California Settled U.S. places * Amboy, California * Amboy, Ge ...
and Mendota. US 52 then turns due south and then east, crossing
I-39 Interstate 39 (I-39) is a highway in the Midwestern United States. I-39 runs from Normal, Illinois, at I-55 to State Trunk Highway 29 (WIS 29) in the town of Rib Mountain, Wisconsin, which is approximately south of Wausau. I- ...
near
Troy Grove Troy Grove is a village in LaSalle County, Illinois, United States. The population was 225 at the 2020 census, down from 250 at the 2010 census. It is part of the Ottawa, IL Micropolitan Statistical Area. Troy Grove is notable as the birthplace ...
. It continues east, passing through Shorewood and then through the southern portion of Joliet, where it is a major thoroughfare in the city of Joliet (Jefferson Street), avoiding the city of
Chicago (''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name ...
proper. It joins with US 45 through Kankakee, thereafter running concurrently with US 24, east of
Watseka Watseka or Watchekee (c. 1810–1878) was a Potawatomi Native American woman, born in Illinois, and named for the heroine of a Potawatomi legend. Her uncle was Tamin, the chief of the Kankakee Potawatomi Indians. She was also known by the ...
to the
Indiana Indiana () is a U.S. state in the Midwestern United States. It is the 38th-largest by area and the 17th-most populous of the 50 States. Its capital and largest city is Indianapolis. Indiana was admitted to the United States as the 19th s ...
state line.


Indiana

In
Indiana Indiana () is a U.S. state in the Midwestern United States. It is the 38th-largest by area and the 17th-most populous of the 50 States. Its capital and largest city is Indianapolis. Indiana was admitted to the United States as the 19th s ...
, US 52 runs in a northwest–southeast direction. It passes through
Lafayette Lafayette or La Fayette may refer to: People * Lafayette (name), a list of people with the surname Lafayette or La Fayette or the given name Lafayette * House of La Fayette, a French noble family ** Gilbert du Motier, Marquis de Lafayette (1757� ...
and
Indianapolis Indianapolis (), colloquially known as Indy, is the state capital and most populous city of the U.S. state of Indiana and the seat of Marion County. According to the U.S. Census Bureau, the consolidated population of Indianapolis and Marion ...
. Northwest of Indianapolis, US 52 runs along the same general area as, and is considered an alternative route to,
I-65 Interstate 65 (I-65) is a major north–south Interstate Highway in the central United States. As with most primary Interstates ending in 5, it is a major crosscountry, north–south route, connecting between the Great Lakes and the Gulf ...
. In the Indianapolis area, it is overlapped with I-865 and I-465. East of Indianapolis, it is considered an alternative to
I-74 } Interstate 74 (I-74) is an Interstate Highway in the Midwestern and Southeastern United States. Its western end is at an interchange with I-80 in Davenport, Iowa (Quad Cities); the eastern end of its Midwest segment is at an interchange ...
before joining it near the Ohio border. When US 52 went through Downtown Indianapolis, it went onto Brookville Road, then turned left onto English Avenue. It then joined US 421 when it turned onto Southeastern Avenue. US 52/US 421 joined US 40 when it turned onto Washington Street. It then split into Washington Street (westbound) and Maryland Street (eastbound). US 52 then turned onto West Street (from West Street, it turned onto Maryland Street). US 52 turned on 16th Street, where it would overlap US 136. It then turned onto Lafayette Road, which became Indianapolis Road when reaching Zionsville. When I-65 was completed through Downtown Indianapolis, US 52 got on I-65 from the Lafayette Road interchange, and traveled on I-65 the rest of the way. In 1970, the route was re-routed onto the south belt of I-465 from Brookville Road to I-65. It was re-routed again on its current route around Indianapolis in either 2000 or 2001.


Ohio

US 52 enters
Ohio Ohio () is a state in the Midwestern region of the United States. Of the fifty U.S. states, it is the 34th-largest by area, and with a population of nearly 11.8 million, is the seventh-most populous and tenth-most densely populated. The sta ...
concurrently with I-74 in northwestern Hamilton County. US 52 then merges with
I-75 Interstate 75 (I-75) is a major north–south Interstate Highway in the Great Lakes and Southeastern regions of the United States. As with most Interstates that end in 5, it is a major cross-country, north–south route, traveling from St ...
from I-74's terminus and exits onto Hopple Street in
Cincinnati Cincinnati ( ) is a city in the U.S. state of Ohio and the county seat of Hamilton County. Settled in 1788, the city is located at the northern side of the confluence of the Licking and Ohio rivers, the latter of which marks the state line wit ...
. It runs along Central Parkway and Central Avenue through downtown and then skirts the Cincinnati riverfront along Mehring Way past
Paul Brown Stadium Paycor Stadium, previously known as Paul Brown Stadium, is an outdoor football stadium in Cincinnati, Ohio. It is the home venue of the Cincinnati Bengals of the National Football League and opened on August 19, 2000. Originally named after the B ...
,
Great American Ball Park Great American Ball Park is a baseball stadium in Cincinnati, Ohio. It served as the home stadium of the Cincinnati Reds of Major League Baseball (MLB), and opened on March 31, 2003, replacing Cinergy Field (formerly Riverfront Stadium), the R ...
, and
Heritage Bank Center Heritage Bank Center is an indoor arena located in downtown Cincinnati, next to the Great American Ball Park. It was completed in September 1975 and named Riverfront Coliseum because of its placement next to Riverfront Stadium. In 1997, the fa ...
(formerly U.S. Bank Arena), onto Pete Rose Way and Riverside Drive. From Cincinnati eastward, US 52 generally follows the
Ohio River The Ohio River is a long river in the United States. It is located at the boundary of the Midwestern and Southern United States, flowing southwesterly from western Pennsylvania to its mouth on the Mississippi River at the southern tip of Illino ...
. There is a brief concurrency with
I-275 Interstate 275 (I-275) may refer to: *Interstate 275 (Florida), a loop through Tampa, St. Petersburg, and Bradenton in Florida *Interstate 275 (Michigan), a western bypass of Detroit, Michigan * Interstate 275 (Ohio–Indiana–Kentucky), a full bel ...
near
California California is a U.S. state, state in the Western United States, located along the West Coast of the United States, Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the List of states and territori ...
, a neighborhood on the far eastern edge of the city of Cincinnati. Towns along its path include New Richmond,
Aberdeen Aberdeen (; sco, Aiberdeen ; gd, Obar Dheathain ; la, Aberdonia) is a city in North East Scotland, and is the third most populous city in the country. Aberdeen is one of Scotland's 32 local government council areas (as Aberdeen City), and ...
, Ripley and
Manchester Manchester () is a city in Greater Manchester, England. It had a population of 552,000 in 2021. It is bordered by the Cheshire Plain to the south, the Pennines to the north and east, and the neighbouring city of Salford to the west. The t ...
. The section between I-275 and New Richmond was modernized in the 1960s; parts of the old route run parallel to the newer highway. Around
Portsmouth Portsmouth ( ) is a port and city in the ceremonial county of Hampshire in southern England. The city of Portsmouth has been a unitary authority since 1 April 1997 and is administered by Portsmouth City Council. Portsmouth is the most dens ...
and Ironton US 52 has several
freeway A controlled-access highway is a type of highway that has been designed for high-speed vehicular traffic, with all traffic flow—ingress and egress—regulated. Common English terms are freeway, motorway and expressway. Other similar terms ...
or
expressway Expressway may refer to: * Controlled-access highway, the highest-grade type of highway with access ramps, lane markings, etc., for high-speed traffic. * Limited-access road, a lower grade of highway or arterial road. *Expressway, the fictional s ...
sections. In Portsmouth, US 52 intersects US 23. At
Chesapeake Chesapeake often refers to: *Chesapeake people, a Native American tribe also known as the Chesepian * The Chesapeake, a.k.a. Chesapeake Bay *Delmarva Peninsula, also known as the Chesapeake Peninsula Chesapeake may also refer to: Populated plac ...
, US 52 crosses the Ohio River into
Huntington, West Virginia Huntington is a city in Cabell and Wayne counties in the U.S. state of West Virginia. It is the county seat of Cabell County, and the largest city in the Huntington–Ashland metropolitan area, sometimes referred to as the Tri-State Area. A h ...
. The sections of US 52 that follow the Ohio River are known as the Ohio River Scenic Byway, which is part of the
National Scenic Byway A National Scenic Byway is a road recognized by the United States Department of Transportation for one or more of six "intrinsic qualities": archeological, cultural, historic, natural, recreational, and scenic. The program was established by Co ...
Project. The section between State Route 125 (SR 125) and SR 73 (near Portsmouth) is also designated as Scenic Scioto Heritage Trail. This portion of US 52, along the Ohio between Cincinnati and Huntington, is the only part where it falls in geographical sequence, south of US 50 and north of US 60. US 52 passes by the birthplace of President
Ulysses S. Grant Ulysses S. Grant (born Hiram Ulysses Grant ; April 27, 1822July 23, 1885) was an American military officer and politician who served as the 18th president of the United States from 1869 to 1877. As Commanding General, he led the Union Ar ...
in Point Pleasant.


West Virginia and Kentucky

US 52 serves western and southern portions of
West Virginia West Virginia is a state in the Appalachian, Mid-Atlantic and Southeastern regions of the United States.The Census Bureau and the Association of American Geographers classify West Virginia as part of the Southern United States while the Bur ...
, running from Huntington to Bluefield. The highway is undergoing a major expansion project which began in 2007 and at current funding levels is likely to take many years to finish. During its run through West Virginia, US 52 twice enters
Kentucky Kentucky ( , ), officially the Commonwealth of Kentucky, is a state in the Southeastern region of the United States and one of the states of the Upper South. It borders Illinois, Indiana, and Ohio to the north; West Virginia and Virginia to ...
briefly, along the
Williamson, West Virginia Williamson is a city in Mingo County, West Virginia, United States, situated along the Tug Fork River. The population was 3,191 at the 2010 census. It is the county seat of Mingo County, and is the county's largest and most populous city. Willia ...
, bypass, in order to prevent the blasting of several hillsides in West Virginia. These stretches were completed in 1996 as part of the
Corridor G U.S. Route 119 (US 119) is a spur of US 19. It is a north–south route (on a northeast-southwest alignment) that was an original United States highway of 1926. It is Corridor G of the Appalachian Development Highway System (ADHS) east of US ...
(
U.S. Route 119 U.S. Route 119 (US 119) is a spur of US 19. It is a north–south route (on a northeast-southwest alignment) that was an original United States highway of 1926. It is Corridor G of the Appalachian Development Highway System (ADHS) east of US ...
) project. The speed limit in West Virginia is , but drops to along the Kentucky portions, as Kentucky law states that any non-freeway (as is US 52) must not have a higher speed limit. In each instance, however, US 52 re-enters West Virginia.


Virginia

US 52 enters Virginia from West Virginia, and in Virginia closely follows
I-77 Interstate 77 (I-77) is a north–south Interstate Highway in the eastern United States. It traverses diverse terrain, from the mountainous state of West Virginia to the rolling farmlands of North Carolina and Ohio. It largely supplants the ...
. It enters southwestern Virginia near Bluefield and passes through
Wytheville Wytheville is a town in, and the county seat of, Wythe County, in southwestern Virginia, United States. It is named after George Wythe, a signer of the United States Declaration of Independence, and mentor to Thomas Jefferson. Wytheville's populat ...
and Hillsville before leaving the state south of
Cana Cana of Galilee ( grc, Κανὰ τῆς Γαλιλαίας; ar, قانا الجليل , translit= Qana al-Jalil , lit=Qana of the Galilee) is the location of the Marriage at Cana, at which the miracle of turning water into wine took place in ...
.


North Carolina

US 52 enters
North Carolina North Carolina () is a state in the Southeastern region of the United States. The state is the 28th largest and 9th-most populous of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, Georgia and So ...
just northwest of Mount Airy. It passes Pilot Mountain, one of the most distinctive natural features in North Carolina. Through the
Piedmont Triad The Piedmont Triad (or simply the Triad) is a metropolitan region in the north-central part of the U.S. state of North Carolina anchored by three cities: Greensboro, North Carolina, Greensboro, Winston-Salem, North Carolina, Winston-Salem, and H ...
region, US 52 is mostly a controlled-access
freeway A controlled-access highway is a type of highway that has been designed for high-speed vehicular traffic, with all traffic flow—ingress and egress—regulated. Common English terms are freeway, motorway and expressway. Other similar terms ...
. The route joins I-85 Business into Lexington and overlaps
I-85 Interstate 85 (I-85) is a major Interstate Highway in the Southeastern United States. Its southern terminus is at an interchange with Interstate 65, I-65 in Montgomery, Alabama; its northern terminus is an interchange with Interstate 95, I ...
around
Salisbury Salisbury ( ) is a cathedral city in Wiltshire, England with a population of 41,820, at the confluence of the rivers Avon, Nadder and Bourne. The city is approximately from Southampton and from Bath. Salisbury is in the southeast of Wil ...
. The segment of US 52 from
I-40 Interstate 40 (I-40) is a major east–west Interstate Highway running through the south-central portion of the United States. At a length of , it is the third-longest Interstate Highway in the country, after I-90 and I-80. From west to ea ...
in
Winston-Salem Winston-Salem is a city and the county seat of Forsyth County, North Carolina, United States. In the 2020 census, the population was 249,545, making it the second-largest municipality in the Piedmont Triad region, the 5th most populous city in N ...
to Lexington has been upgraded to
Interstate Highway standards Standards for Interstate Highways in the United States are defined by the American Association of State Highway and Transportation Officials (AASHTO) in the publication ''A Policy on Design Standards: Interstate System''. For a certain highway to ...
; I-285 is co-signed along this segment. The segment from northern Winston-Salem to just south of Mount Airy is expected to form part of the
I-74 } Interstate 74 (I-74) is an Interstate Highway in the Midwestern and Southeastern United States. Its western end is at an interchange with I-80 in Davenport, Iowa (Quad Cities); the eastern end of its Midwest segment is at an interchange ...
corridor through North Carolina. South of the Triad area, after splitting from I-85 in
Salisbury Salisbury ( ) is a cathedral city in Wiltshire, England with a population of 41,820, at the confluence of the rivers Avon, Nadder and Bourne. The city is approximately from Southampton and from Bath. Salisbury is in the southeast of Wil ...
, US 52 is typically a two-lane route linking some of the state's smaller cities and towns. Albemarle is the largest municipality along this segment of US 52 to the South Carolina state line.


South Carolina

US 52 enters
South Carolina )''Animis opibusque parati'' ( for, , Latin, Prepared in mind and resources, links=no) , anthem = " Carolina";" South Carolina On My Mind" , Former = Province of South Carolina , seat = Columbia , LargestCity = Charleston , LargestMetro = ...
northeast of Cheraw. From
Darlington Darlington is a market town in the Borough of Darlington, County Durham, England. The River Skerne flows through the town; it is a tributary of the River Tees. The Tees itself flows south of the town. In the 19th century, Darlington underwen ...
southward it is a multilane highway and
freeway A controlled-access highway is a type of highway that has been designed for high-speed vehicular traffic, with all traffic flow—ingress and egress—regulated. Common English terms are freeway, motorway and expressway. Other similar terms ...
, passing through
Florence Florence ( ; it, Firenze ) is a city in Central Italy and the capital city of the Tuscany region. It is the most populated city in Tuscany, with 383,083 inhabitants in 2016, and over 1,520,000 in its metropolitan area.Bilancio demografico an ...
, Lake City,
Kingstree Kingstree is a city and the county seat of Williamsburg County, South Carolina, United States. The population was 3,328 at the 2010 census. History The original town was laid out as Williamsburg by the Lords Proprietors in colonial times, but a ...
,
Moncks Corner Moncks Corner is a town in and the county seat of Berkeley County, South Carolina, United States. The population was 7,885 at the 2010 census. As defined by the U.S. Census Bureau, Moncks Corner is included within the Charleston-North Charleston-S ...
and
North Charleston North Charleston is the third-largest city in the state of South Carolina.City Planning Department (2008-07)City of North Charleston boundary map. City of North Charleston. Retrieved January 21, 2011. On June 12, 1972, the city of North Charlest ...
before US 52's terminus at the intersection of Meeting and Line Streets in Charleston.


History

Historically, US 52 was routed along
University Avenue A university () is an educational institution, institution of higher education, higher (or Tertiary education, tertiary) education and research which awards academic degrees in several Discipline (academia), academic disciplines. Universities ty ...
between
Minneapolis Minneapolis () is the largest city in Minnesota, United States, and the county seat of Hennepin County. The city is abundant in water, with thirteen lakes, wetlands, the Mississippi River, creeks and waterfalls. Minneapolis has its origins ...
and
St. Paul Paul; grc, Παῦλος, translit=Paulos; cop, ⲡⲁⲩⲗⲟⲥ; hbo, פאולוס השליח (previously called Saul of Tarsus;; ar, بولس الطرسوسي; grc, Σαῦλος Ταρσεύς, Saũlos Tarseús; tr, Tarsuslu Pavlus; ...
. In the 1980s and 1990s, the highway was gradually shifted onto its present route along
Interstate 94 Interstate 94 (I-94) is an east–west Interstate Highway connecting the Great Lakes and northern Great Plains regions of the United States. Its western terminus is just east of Billings, Montana, at a junction with I-90; its eastern ter ...
. However, there was a gap in the definition of the highway for a few years until 1995. Since then, it has been routed along the interstate between the
Twin Cities Twin cities are a special case of two neighboring cities or urban centres that grow into a single conurbation – or narrowly separated urban areas – over time. There are no formal criteria, but twin cities are generally comparable in statu ...
, although as of 2007, there was still a sign on University Avenue entering
Hennepin County Hennepin County ( ) is a county in the U.S. state of Minnesota. Its county seat is Minneapolis, the state's most populous city. The county is named in honor of the 17th-century explorer Father Louis Hennepin. The county extends from Minneapol ...
telling motorists to follow County Highways 36 and 37 to reach US 52—which kept them on University, then on 4th St. for historic westbound US 52. Historic westbound US 52 then crossed the Central Avenue bridge (current
Minnesota State Highway 65 Minnesota State Highway 65 (MN 65) is a highway in the east–central and northeast parts of the U.S. state of Minnesota, which starts at its split from I-35W, skipping past the downtown Minneapolis core, only to resume at the intersection with ' ...
) and turned onto the current routing of County Highway 81 northwest to Osseo. It then followed the current route of U.S. Highway 169 north to Anoka. In
Rochester, Minnesota Rochester is a city in the U.S. state of Minnesota and the county seat of Olmsted County. Located on rolling bluffs on the Zumbro River's south fork in Southeast Minnesota, the city is the home and birthplace of the renowned Mayo Clinic. Acco ...
, US 52 was recently expanded to six lanes. Long-term plans have US 52 from St. Paul to
Interstate 90 Interstate 90 (I-90) is an east–west transcontinental freeway and the longest Interstate Highway in the United States at . It begins in Seattle, Washington, and travels through the Pacific Northwest, Mountain West, Great Plains, Midwest, and ...
becoming a freeway, and some have suggested that when the conversion is complete, the freeway should become a spur route for
Interstate 90 Interstate 90 (I-90) is an east–west transcontinental freeway and the longest Interstate Highway in the United States at . It begins in Seattle, Washington, and travels through the Pacific Northwest, Mountain West, Great Plains, Midwest, and ...
(I-X90). Currently,
Interstate 90 Interstate 90 (I-90) is an east–west transcontinental freeway and the longest Interstate Highway in the United States at . It begins in Seattle, Washington, and travels through the Pacific Northwest, Mountain West, Great Plains, Midwest, and ...
has no spur routes in Minnesota. On April 10, 2015, a
rockslide A rockslide is a type of landslide caused by rock failure in which part of the bedding plane of failure passes through compacted rock and material collapses ''en masse'' and not in individual blocks. Note that a rockslide is similar to an avalanc ...
dropped a boulder the size of a house onto the westbound lanes of US 52 in Lawrence County just east of the bridge over the
Ohio River The Ohio River is a long river in the United States. It is located at the boundary of the Midwestern and Southern United States, flowing southwesterly from western Pennsylvania to its mouth on the Mississippi River at the southern tip of Illino ...
to
Ashland, Kentucky Ashland is a home rule-class city in Boyd County, Kentucky, United States. The largest city in Boyd County, Ashland is located upon a southern bank of the Ohio River at the state border with Ohio and near West Virginia. The population was 21,6 ...
, leading to closures and detours while two days of cleanup took place.


U.S. Route 121 (1926)

Established in 1926, US 121 traversed from
Lexington, North Carolina Lexington is the county seat of Davidson County, North Carolina, United States. As of the 2010 census, the city had a population of 18,931. It is located in central North Carolina, south of Winston-Salem. Major highways include I-85, I-85B, U ...
, to
Max Meadows, Virginia Max Meadows is a census-designated place (CDP) in Wythe County, Virginia, United States. The population was 562 at the 2010 census. History The Foster Falls Historic District, Graham's Forge Mill, Sanders Farm, and Jackson Ferry Shot Tower are ...
, estimated to be . In
North Carolina North Carolina () is a state in the Southeastern region of the United States. The state is the 28th largest and 9th-most populous of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, Georgia and So ...
it overlapped with NC 66; in
Virginia Virginia, officially the Commonwealth of Virginia, is a state in the Mid-Atlantic and Southeastern regions of the United States, between the Atlantic Coast and the Appalachian Mountains. The geography and climate of the Commonwealth ar ...
it was overlapped with
SR 15 Route 15, or Highway 15, can refer to: For roads named A15, see A15 roads. International * Asian Highway 15 * European route E15 * European route E015 Australia New South Wales * Hunter Expressway * New England Highway and other local Ne ...
. In 1934, US 52 was extended southeast into Virginia and North Carolina, and replaced all of US 121.


Future


Ohio

Long-term plans call for
I-74 } Interstate 74 (I-74) is an Interstate Highway in the Midwestern and Southeastern United States. Its western end is at an interchange with I-80 in Davenport, Iowa (Quad Cities); the eastern end of its Midwest segment is at an interchange ...
to be expanded eastward along the current US 52 corridor from its current eastern terminus of
I-75 Interstate 75 (I-75) is a major north–south Interstate Highway in the Great Lakes and Southeastern regions of the United States. As with most Interstates that end in 5, it is a major cross-country, north–south route, traveling from St ...
in
Cincinnati Cincinnati ( ) is a city in the U.S. state of Ohio and the county seat of Hamilton County. Settled in 1788, the city is located at the northern side of the confluence of the Licking and Ohio rivers, the latter of which marks the state line wit ...
to US 23, which has been proposed to be upgraded to
Interstate Highway standards Standards for Interstate Highways in the United States are defined by the American Association of State Highway and Transportation Officials (AASHTO) in the publication ''A Policy on Design Standards: Interstate System''. For a certain highway to ...
and be signed as
I-73 Interstate 73 (I-73) is a north–south Interstate Highway, located within the US state of North Carolina. Currently, there is one continuous section of I-73, totaling , first traversing the U.S. Route 220 (US 220) freeway from ...
in
Portsmouth Portsmouth ( ) is a port and city in the ceremonial county of Hampshire in southern England. The city of Portsmouth has been a unitary authority since 1 April 1997 and is administered by Portsmouth City Council. Portsmouth is the most dens ...
. Lack of sufficient funding has hindered construction upgrades for both freeways in Ohio.


Major intersections

;North Dakota : at the
Canada–United States border The border between Canada and the United States is the longest international border in the world. The terrestrial boundary (including boundaries in the Great Lakes, Atlantic, and Pacific coasts) is long. The land border has two sections: Can ...
in
Portal Portal often refers to: * Portal (architecture), an opening in a wall of a building, gate or fortification, or the extremities (ends) of a tunnel Portal may also refer to: Arts and entertainment Gaming * ''Portal'' (series), two video games ...
: northwest of
Burlington Burlington may refer to: Places Canada Geography * Burlington, Newfoundland and Labrador * Burlington, Nova Scotia * Burlington, Ontario, the most populous city with the name "Burlington" * Burlington, Prince Edward Island * Burlington Bay, no ...
. The highways travel concurrently to southeast of
Minot Minot ( ) is a city in and the county seat of Ward County, North Dakota, Ward County, North Dakota, United States, in the state's north-central region. It is most widely known for the Minot Air Force Base, Air Force base approximately north of ...
. : in Minot : in Carrington. The highways travel concurrently to Jamestown. : in Jamestown. The highways travel concurrently to
Saint Paul, Minnesota Saint Paul (abbreviated St. Paul) is the List of capitals in the United States, capital of the U.S. state of Minnesota and the county seat of Ramsey County, Minnesota, Ramsey County. Situated on high bluffs overlooking a bend in the Mississip ...
. : in West Fargo : in Fargo ;Minnesota : in Moorhead : in Fergus Falls Township. The highways travel concurrently to the
Buse Buse is a feminine given first name in Turkey, meaning "kiss" in Persian (بوسه) and Turkish, and a surname in other languages, and may refer to: Given name * Buse Arıkazan (born 1994), Turkish pole vaulters * Buse Güngör (born 1994), Turk ...
Dane Prairie township line. : in Sauk Centre : in Maple Grove. I-694/US 52 travels concurrently to
Brooklyn Center Brooklyn Center is a first-ring suburban city in Hennepin County, Minnesota, United States in the Minneapolis–Saint Paul metropolitan area. In 1911, the area became a village formed from parts of Brooklyn Township and Crystal Lake Township. I ...
. : on the Maple Grove– Brooklyn Park city line : in
Minneapolis Minneapolis () is the largest city in Minnesota, United States, and the county seat of Hennepin County. The city is abundant in water, with thirteen lakes, wetlands, the Mississippi River, creeks and waterfalls. Minneapolis has its origins ...
. US 12/US 52 travels concurrently to Saint Paul. : in Minneapolis. The highways travel concurrently, but on separate lanes, through the city. : in Saint Paul. The highways travel concurrently, but on separate lanes, through the city. : in Saint Paul. US 10/US 52 travels concurrently through the city. : in
Inver Grove Heights Inver Grove Heights is a city in Dakota County, Minnesota, United States. The population was 35,801 at the 2020 census. The city was formed on March 9, 1965, with the merger of the village of Inver Grove and Inver Grove Township. It is one of 1 ...
: in
Rochester Rochester may refer to: Places Australia * Rochester, Victoria Canada * Rochester, Alberta United Kingdom *Rochester, Kent ** City of Rochester-upon-Medway (1982–1998), district council area ** History of Rochester, Kent ** HM Prison ...
. The highways travel concurrently through the city. : in Rochester. The highways travel concurrently through the city. : in Marion Township ;Iowa : in Post Township. The highways travel concurrently to Giard Township. : in
Dyersville Dyersville is a city in eastern Delaware County and western Dubuque County in the U.S. state of Iowa. It is part of the Dubuque, Iowa, Metropolitan Statistical Area. The population was 4,477 at the time of the 2020 census, up from 4,035 in 200 ...
The highways travel concurrently to the
Southwest Arterial U.S. Highway 52 (US 52) is a United States Numbered Highway in northeast Iowa. The route begins at the Dale Gardner Veterans Memorial Bridge over the Mississippi River between Sabula and Savanna, Illinois. From Sabula, it heads north along th ...
in Dubuque. : near
Dubuque Dubuque (, ) is the county seat of Dubuque County, Iowa, United States, located along the Mississippi River. At the time of the 2020 census, the population of Dubuque was 59,667. The city lies at the junction of Iowa, Illinois, and Wisconsin, a r ...
. The highways travel concurrently south of the city. : in Union Township ;Illinois : on the
Amboy Amboy may refer to: Places * Amboy, Córdoba, village in Calamuchita Department, Córdoba province, Argentina United States * Amboy Crater, feature in Mojave National Preserve, California Settled U.S. places * Amboy, California * Amboy, Ge ...
Franklin Grove Franklin Grove is a village in Lee County, Illinois, United States. The population was 1,021 at the 2010 census, down from 1,052 in 2000. History Franklin Grove was named for James R. Franklin, a pioneer who settled in a grove near the town site ...
township line : in Mendota : on the
Troy Grove Troy Grove is a village in LaSalle County, Illinois, United States. The population was 225 at the 2020 census, down from 250 at the 2010 census. It is part of the Ottawa, IL Micropolitan Statistical Area. Troy Grove is notable as the birthplace ...
Ophir Ophir (; ) is a port or region mentioned in the Bible, famous for its wealth. King Solomon received a shipment from Ophir every three years (1 Kings 10:22) which consisted of gold, silver, sandalwood, pearls, ivory, apes, and peacocks. ...
township line : in Shorewood : in Joliet. The highways travel concurrently through the city. : in Joliet : in Peotone Township. The highways travel concurrently to Ashkum Township. : in Kankakee : in Concord Township. The highways travel concurrently to
Kentland, Indiana Kentland is a town in Jefferson Township, Newton County, Indiana, Jefferson Township, Newton County, Indiana, Newton County, in the U.S. state of Indiana. The population was 1,641 at the 2020 census. History The town was founded in 1860 as "Kent", ...
. ;Indiana : in Kentland. US 41/US 52 travels concurrently to Richland Township. : in Montmorenci. The highways travel concurrently to Wabash Township. : in Center Township. The highways travel concurrently to Eagle Township. : in Eagle Township. I-865/US 52 travels concurrently through the township. : in Eagle Township. I-465/US 52 travels concurrently to
Indianapolis Indianapolis (), colloquially known as Indy, is the state capital and most populous city of the U.S. state of Indiana and the seat of Marion County. According to the U.S. Census Bureau, the consolidated population of Indianapolis and Marion ...
. : in Indianapolis. The highways travel concurrently through the city. : in
Carmel Carmel may refer to: * Carmel (biblical settlement), an ancient Israelite town in Judea * Mount Carmel, a coastal mountain range in Israel overlooking the Mediterranean Sea * Carmelites, a Roman Catholic mendicant religious order Carmel may also ...
. The highways travel concurrently to Indianapolis. : in Indianapolis : in
Lawrence Lawrence may refer to: Education Colleges and universities * Lawrence Technological University, a university in Southfield, Michigan, United States * Lawrence University, a liberal arts university in Appleton, Wisconsin, United States Preparator ...
. The highways travel concurrently to Indianapolis. : in Indianapolis : in Indianapolis. The highways travel concurrently through the city. : in Indianapolis : in Harrison Township. The highways travel concurrently to
Cincinnati, Ohio Cincinnati ( ) is a city in the U.S. state of Ohio and the county seat of Hamilton County. Settled in 1788, the city is located at the northern side of the confluence of the Licking and Ohio rivers, the latter of which marks the state line wit ...
. ;Ohio : in Whitewater Township. The highways travel concurrently to Taylor Creek. : in Cincinnati. The highways travel concurrently through the city. : in Cincinnati : in Cincinnati. I-75/US 52 travels concurrently through the city. : in Cincinnati. The highways travel concurrently through the city. : in Cincinnati. The highways travel concurrently through the city. : in Cincinnati. The highways travel concurrently through the city. : in Cincinnati : in Cincinnati. US 27/US 52 travels concurrently through the city. : in Cincinnati. The highways travel concurrently to Anderson Township. : in Ripley. US 52/US 62 travels concurrently to
Aberdeen Aberdeen (; sco, Aiberdeen ; gd, Obar Dheathain ; la, Aberdonia) is a city in North East Scotland, and is the third most populous city in the country. Aberdeen is one of Scotland's 32 local government council areas (as Aberdeen City), and ...
. US 52/US 68 travels concurrently to Huntington Township. : in
Portsmouth Portsmouth ( ) is a port and city in the ceremonial county of Hampshire in southern England. The city of Portsmouth has been a unitary authority since 1 April 1997 and is administered by Portsmouth City Council. Portsmouth is the most dens ...
: in Sciotodale ;West Virginia : in Huntington : in Huntington. The highways travel concurrently to
Kenova Kenova is a city in Wayne County, West Virginia, United States, situated at the confluence of the Ohio and Big Sandy Rivers. Located near a tristate border, the city's name is a portmanteau of Kentucky, Ohio, and Virginia (Va). Founded in ...
. : northeast of Nolan. The highways travel concurrently to Williamson. ;Kentucky : No major intersections ;West Virginia : in Bluefield. The highways travel concurrently through the city. : in Bluefield. The highways travel concurrently through the city. : in Bluefield. The highways travel concurrently to north-northwest of
Rocky Gap, Virginia Rocky Gap is an unincorporated community that is located in Bland County in the U.S. state of Virginia. In the year of 2016, there was an estimate that there were a total of 511 people living in Rocky Gap.2 Rocky Gap has one zip code (24366). T ...
. ;Virginia : in Rocky Gap : west of Bland : in
Wytheville Wytheville is a town in, and the county seat of, Wythe County, in southwestern Virginia, United States. It is named after George Wythe, a signer of the United States Declaration of Independence, and mentor to Thomas Jefferson. Wytheville's populat ...
. I-81/US 52 travel concurrently to
Fort Chiswell Chiswell , sometimes , is a small village at the southern end of Chesil Beach, in Underhill, on the Isle of Portland in Dorset. It is the oldest settlement on the island, having formerly been known as Chesilton. The small bay at Chiswell is ca ...
. : in Wytheville. The highways travel concurrently to Fort Chiswell. : in Wytheville. The highways travel concurrently to Fort Chiswell. : in Hillsville : in Hillsville ;North Carolina : in Mount Airy : southeast of Mount Airy : in
Winston-Salem Winston-Salem is a city and the county seat of Forsyth County, North Carolina, United States. In the 2020 census, the population was 249,545, making it the second-largest municipality in the Piedmont Triad region, the 5th most populous city in N ...
: in Winston-Salem. : in Winston-Salem : in Winston-Salem. I-285/US 52 travel concurrently to Lexington. : in Lexington : in Lexington. The highways travel concurrently to northeast of Spencer. : in Lexington. I-85/US 52 travel concurrently to
Salisbury Salisbury ( ) is a cathedral city in Wiltshire, England with a population of 41,820, at the confluence of the rivers Avon, Nadder and Bourne. The city is approximately from Southampton and from Bath. Salisbury is in the southeast of Wil ...
. : in Wadesboro. The highways travel concurrently through the city. ;South Carolina : in Cheraw. The highways travel concurrently to south-southwest of Cheraw. : in
Society Hill Society Hill is a historic neighborhood in Center City Philadelphia, with a population of 6,215 . Settled in the early 1680s, Society Hill is one of the oldest residential neighborhoods in Philadelphia.The Center City District dates the Free Soc ...
. US 15/US 52 travels concurrently to southwest of Society Hill. US 52/US 401 travels concurrently to
Darlington Darlington is a market town in the Borough of Darlington, County Durham, England. The River Skerne flows through the town; it is a tributary of the River Tees. The Tees itself flows south of the town. In the 19th century, Darlington underwen ...
. : northwest of
Florence Florence ( ; it, Firenze ) is a city in Central Italy and the capital city of the Tuscany region. It is the most populated city in Tuscany, with 383,083 inhabitants in 2016, and over 1,520,000 in its metropolitan area.Bilancio demografico an ...
: in Florence : in Florence. The highways travel concurrently to Effingham. : north of Lake City : east of Greeleyville : in Goose Creek : in
North Charleston North Charleston is the third-largest city in the state of South Carolina.City Planning Department (2008-07)City of North Charleston boundary map. City of North Charleston. Retrieved January 21, 2011. On June 12, 1972, the city of North Charlest ...
. The highways travel concurrently through the city. : in North Charleston : in North Charleston : in Charleston : in Charleston : Line Street/Meeting Street in Charleston


See also

*
Interstate 74 } Interstate 74 (I-74) is an Interstate Highway in the Midwestern and Southeastern United States. Its western end is at an interchange with I-80 in Davenport, Iowa (Quad Cities); the eastern end of its Midwest segment is at an interchange ...


Related routes

* U.S. Route 152


Special and suffixed routes

* U.S. Route 52 Spur in
Charleston, South Carolina Charleston is the largest city in the U.S. state of South Carolina, the county seat of Charleston County, and the principal city in the Charleston–North Charleston metropolitan area. The city lies just south of the geographical midpoint o ...


References


External links


Endpoints of U.S. Highway 52

Illinois Highway Ends: US 52

Indiana Highway Ends: US 52


{{DEFAULTSORT:52 Roads in Cincinnati Scenic byways in Ohio U.S. Highways in Indiana U.S. Highways in Ohio United States Numbered Highway System U.S. Highways in Kentucky