Uroš Desnica may refer to:
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Uroš Desnica (politician) (1874–1941), Croatian Serb politician, grandfather of Uroš Desnica born in 1944
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Uroš Desnica (scientist) (1944–2021), Croatian scientist, grandson of Uroš Desnica born in 1874
{{Hndis, Desnica, Uroš