TCPy or 3,5,6-trichloro-2-pyridinol is a cyclic hydrocarbon, specifically a

chlorinated In chemistry, halogenation is a chemical reaction that entails the introduction of one or more halogens into a compound. Halide-containing compounds are pervasive, making this type of transformation important, e.g. in the production of polyme ...

version of 2-pyridone. Pesticides can be a precursor to TCPy. TCPy is a metabolite of the herbicide

triclopyr Triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid) is an organic compound in the pyridine group that is used as a systemic foliar herbicide and fungicide. Uses Triclopyr is used to control broadleaf weeds while leaving grasses and conifers ...

, and of the insecticides

chlorpyrifos Chlorpyrifos (CPS), also known as Chlorpyrifos ethyl, is an organophosphate pesticide that has been used on crops, animals, and buildings, and in other settings, to kill several pests, including insects and worms. It acts on the nervous systems ...

and chlorpyrifos-methyl. A study in Massachusetts reported a correlation between exposure to TCPy and lower

testosterone Testosterone is the primary sex hormone and anabolic steroid in males. In humans, testosterone plays a key role in the development of Male reproductive system, male reproductive tissues such as testes and prostate, as well as promoting secondar ...

levels in men. According to this source, exposure is "widespread" and of "potential public health importance".

References

{{Insecticides Chloroarenes 2-Pyridones