Lymphotoxin is a member of the
tumor necrosis factor (TNF) superfamily of cytokines, whose members are responsible for regulating the growth and function of
lymphocyte
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), an ...
s and are expressed by a wide variety of cells in the body.
Lymphotoxin plays a critical role in developing and preserving the framework of
lymphoid organs and of gastrointestinal immune responses, as well as in the activation signaling of both the