THC valine hemisuccinate (THC-VHS, NB-1111, SBI-100) is a synthetic

prodrug A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Instead of administering a drug directly, a corresponding prodrug can be ...

tetrahydrocannabinol Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. It is the principal psychoactive constituent of ''Cannabis'' and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C21H30O2) de ...

, developed at the

University of Mississippi The University of Mississippi (Epithet, byname Ole Miss) is a Public university, public research university in University, near Oxford, Mississippi, United States, with a University of Mississippi Medical Center, medical center in Jackson, Miss ...

as a stabilised formulation for ophthalmic administration, for use in the treatment of

glaucoma Glaucoma is a group of eye diseases that can lead to damage of the optic nerve. The optic nerve transmits visual information from the eye to the brain. Glaucoma may cause vision loss if left untreated. It has been called the "silent thief of ...

and other eye conditions requiring reduction in

intraocular pressure Intraocular pressure (IOP) is the fluid pressure inside the eye. Tonometry is the method eye care professionals use to determine this. IOP is an important aspect in the evaluation of patients at risk of glaucoma. Most tonometers are calibrated t ...

References

Benzochromenes Cannabinoids Prodrugs Carboxamides {{cannabinoid-stub

See also

References