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Sofinnova is the name shared by two
venture capital Venture capital (often abbreviated as VC) is a form of private equity financing that is provided by venture capital firms or funds to startups, early-stage, and emerging companies that have been deemed to have high growth potential or which ha ...
firms, Sofinnova Partners and Sofinnova Ventures. The name Sofinnova is a contraction of the French, "Société de Financement de l’Innovation" or, Innovation Venture Capital Company. Both firms trace their roots back to Sofinnova SA, an investment institution founded in Paris in 1972. The two firms have raised ~$4B since inception and have generally shared a similar investment strategy of financing projects and ideas in the life sciences and technology sectors. The two firms distinguish themselves on the basis of their target geographies, stage of investment, and sectors. They have been independent entities since 1997. *
Sofinnova Partners Sofinnova is the name shared by two venture capital firms, Sofinnova Partners and Sofinnova Ventures. The name Sofinnova is a contraction of the French, "Société de Financement de l’Innovation" or, Innovation Venture Capital Company. Both fi ...
is based in Paris, London, and Milan and focuses primarily on European biotech, medtech, biopharma, and industrial biotech investments, with a similar allocation for the US. * Sofinnova Ventures has offices in Menlo Park, CA, and San Diego, CA, and focuses largely on US biotech investments, with ~20% allocation for Europe. Sofinnova Partners and Sofinnova Ventures have historically shared some of the same Limited Partners, and have co-invested together in various life sciences companies including Flamel, Cerep, Genset, Actelion, Preglem, Movetis, Ascendis, Obseva, Auris and Nucana. The firms have a collegial relationship and exchange information and due diligence. The firms do not have an obligation to disclose deals or to co-invest, but historically have co-invested together in ~10% of their collective investments.


Sofinnova Partners (France, UK, Italy)

Sofinnova Partners is an independent venture capital firm based in
Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. S ...
,
London London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a majo ...
, and
Milan Milan ( , , Lombard: ; it, Milano ) is a city in northern Italy, capital of Lombardy, and the second-most populous city proper in Italy after Rome. The city proper has a population of about 1.4 million, while its metropolitan city h ...
with approximately €2 billion of capital. The firm invests primarily in early-stage companies and corporate spin-offs, in
industrial biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
and in life sciences. The Sofinnova Partners' flagship fund, Sofinnova Capital IX, raised €333M in 2019. Over the last few years, Sofinnova Partners has created a platform strategy to include multiple funds alongside its historic Capital Fund. This includes: * The Sofinnova Telethon Fund, specializing in early‐stage investments in gene and cell therapies * The Sofinnova Crossover I, a fund investing in pre‐ and post‐IPO companies * The Sofinnova MD Start III, a medical device acceleration fund * The Sofinnova Industrial Biotech I Each of these funds is managed by dedicated specialist teams and are unique investment vehicles across the life sciences investment value chain. Sofinnova has financed over 500 companies around the world since its inception in 1972 of which more than 20% have successfully completed an
initial public offering An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investment ...
and more than 20% have been acquired by strategic buyers.


Investments

Sofinnova Partners most recently closed its Sofinnova Telethon Fund at €108 M and has invested in 3 Italian biotech startups in the last 6 months. This fund specializes in early‐stage investments in gene and cell therapies and is based out of Milan, Italy. It also completed fundraising for its ninth private equity fund, Sofinnova Capital IX with €333M raised. Some notable investments from the firm's flagship fund include Innate, Maximiles and NovusPharma from Sofinnova Capital III (€121M). Sofinnova Partners' Capital IV fund, which raised €330M of capital, made it one of the largest venture firms in Europe at the time. In 2005, Sofinnova Partners was named “Fund of the Year” by Private Equity International and “VC Techno House of the Year 2005” by the European Venture Capital Journal (EVCJ) which described Sofinnova's fundraising as the “Fundraising of the Year 2005”. This fund invested in a number of companies including
Taptu Taptu was a social media and technology company that built platforms, tools and applications that enabled content on touch screen mobile devices, including phones running iOS and Android. Taptu was a privately held company that was founded in C ...
. Sofinnova Partners has raised several venture capital funds (see Table). ''Source:
Private Equity Intelligence Preqin is a privately held London-based investment data company that provides financial data and insight on the alternative assets market, as well as tools to support investment in alternatives. By the company's own definition, its data encompas ...
and Sofinnova''


Sofinnova Ventures (USA)

Sofinnova Ventures is an independent venture capital firm based in Menlo Park.


Investments

Sofinnova Ventures has been an active venture investor, investing in some well-known venture investments of the period. Sofinnova Ventures has backed companies including:
Millennium Pharmaceuticals Takeda Oncology (originally Millennium Pharmaceuticals) is a biopharmaceutical company based in Cambridge, Massachusetts. It is a fully owned subsidiary of Takeda Pharmaceutical. Takeda Oncology's research, development and commercialization acti ...
,
Kosan Biosciences Kosan Biosciences, Inc. (stock symbol: KOSN), was a pharmaceutical company which dealt with cancer therapeutics medications. The company was working on advancing two new classes of anticancer agents through clinical development: heat shock prote ...
, Actelion, Intermune,
Seattle Genetics SeaGen was the world's first large scale commercial tidal stream generator. It was four times more powerful than any other tidal stream generator in the world at the time of installation. It was successfully decommissioned by SIMEC Atlant ...
, Cotherix, Threshold Pharmaceuticals, Prestwick, Preglem,
Movetis Movetis was a pharmaceutical company headquartered in Belgium. It was founded in 2006 as a spin-off from parent company Johnson & Johnson. The company specialized in pharmaceuticals for treating gastro-intestinal disorders. The primary drug pr ...
, Intellikine,
Amarin Corporation Amarin may refer to: *Amarin Corporation, an Irish-American biopharmaceutical company * Amarinus, a Roman Catholic saint associated with Saint Praejectus *Saint-Amarin, a commune in France (named after the saint) *Amarin Group, a Thai media and pub ...
, Salveo, and Labrys. The San Francisco office of Sofinnova Ventures was often remembered for having an original 18 ft.
mosasaurus ''Mosasaurus'' (; "lizard of the Meuse River") is the type genus (defining example) of the mosasaurs, an extinct group of aquatic squamate reptiles. It lived from about 82 to 66 million years ago during the Campanian and Maastrichtian stages o ...
in the office of one of the Managing Partners (Mike Powell). Sofinnova Ventures closed their San Francisco office in 2011, and combined their Bay Area offices into a single office on
Sand Hill Road Sand Hill Road, often shortened to just "Sand Hill" or "SHR", is an arterial road in western Silicon Valley, California, running through Palo Alto, Menlo Park, and Woodside, notable for its concentration of venture capital companies. The road h ...
in Menlo Park. Sofinnova Ventures has raised several venture capital funds (see Table). The earlier funds, SVP I through V, were predominantly information technology (IT), wherein the later funds were predominantly life science focused. SVP VIII and IX were exclusively life science only, with emphasis on Phase 2 and 3 drug development. SVP IV was Sofinnova Ventures' initial fund after the reorganization of Sofinnova in 1997. Each of the funds from SVP V through SVP IX exceeded the target raise, and closed at the maximum amount as allowed by the Limited Partner agreements. ''Source:
Private Equity Intelligence Preqin is a privately held London-based investment data company that provides financial data and insight on the alternative assets market, as well as tools to support investment in alternatives. By the company's own definition, its data encompas ...
'' and Sofinnova.


History


1970s: The Founding of Sofinnova

* 1972 - Sofinnova was founded with the backing of several French financial institutions (most notably Crédit National) and was notable at the time for creating the first "American style" venture capital firm in France. Peter Brooke, the founder of
TA Associates TA Associates, founded in 1968, is one of the early modern-era private equity firms in the United States. The firm leads buyouts and minority recapitalizations of profitable growth companies. TA invests across five industry groups: technology, hea ...
, was a board member of Sofinnova SA in its early years. Sofinnova SA quickly established a presence in the European market through the formation of Sofinnova Partners in Paris. Sofinnova SA owned this firm from 1972 until 1997. * 1974 - Sofinnova became the first European venture company to enter the US market launching its US affiliate, Sofinnova, Inc (Sofinnova Ventures). Sofinnova co-founder, Jean Deleage, who would later co-found US venture firm Burr, Egan, Deleage & Co., was appointed the head of the US operation. Sofinnova's US business gained attention for its role as an early backer of
Tandem Computers Tandem Computers, Inc. was the dominant manufacturer of fault-tolerant computer systems for Automated teller machine, ATM networks, banks, stock exchanges, telephone switching centers, and other similar commercial transaction processing applicati ...
and
Genentech Genentech, Inc., is an American biotechnology corporation headquartered in South San Francisco, California. It became an independent subsidiary of Roche in 2009. Genentech Research and Early Development operates as an independent center within R ...
in the early 1980s. * 1976 - Sofinnova co-founder
Jean Deleage Dr. Jean Deleage Ph.D. (1940–2011) was an early venture capital investor responsible for the founding or co-founding of three notable venture capital firms since 1971: Sofinnova, Burr, Egan, Deleage & Co. and Alta Partners. Career Deleage began ...
established the American subsidiary of Sofinnova, called Sofinnova, Inc., in
San Francisco San Francisco (; Spanish language, Spanish for "Francis of Assisi, Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the List of Ca ...
, which eventually became Sofinnova Ventures. Deleage departed Sofinnova in 1979 to co-found another venture capital firm Burr, Egan, Deleage & Co. In 1981, working with Deleage, Sofinnova developed a partnership with Burr, Egan, Deleage & Co. and ultimately other US firms. Jean-Bernard Schmidt, who would later serve as Chairman of Sofinnova, was named the head of US operations of Sofinnova, Inc.


1980s: The Early Growth of Sofinnova

* 1985 - Sofinnova completed an
initial public offering An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investment ...
with a listing on the
Paris Stock Exchange Euronext Paris is France's securities market, formerly known as the Paris Bourse, which merged with the Amsterdam, Lisbon, and Brussels exchanges in September 2000 to form Euronext NV. As of 2022, the 795 companies listed had a combined market ...
. * 1987 - Alain Azan moved to
San Francisco San Francisco (; Spanish language, Spanish for "Francis of Assisi, Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the List of Ca ...
to take over management of Sofinnova Ventures, replacing Jean-Bernard Schmidt. Schmidt would be named Chairman of Sofinnova, retaining that position through 2007. Sofinnova Ventures completed fundraising for SVP I, which was a
private equity fund A private equity fund (abbreviated as PE fund) is a collective investment scheme used for making investments in various equity (and to a lesser extent debt) securities according to one of the investment strategies associated with private equity ...
originally intended to invest in European companies expanding in the US. Ultimately, Sofinnova Venture Partners would shift its focus toward investments in domestic US companies. * 1989 - Sofinnova Partners completed fundraising for Sofinnova Capital, its first
private equity fund A private equity fund (abbreviated as PE fund) is a collective investment scheme used for making investments in various equity (and to a lesser extent debt) securities according to one of the investment strategies associated with private equity ...
in France, with €38M of investor commitments. Sofinnova's investments in this fund include Genset Corporation as well as Cerep, Egide and Flamel.


1990s: The Reorganization of Sofinnova into Sofinnova Partners and Sofinnova Ventures

* 1993 - Sofinnova
delisted In corporate finance, a listing refers to the company's shares being on the list (or board) of stock that are officially traded on a stock exchange. Some stock exchanges allow shares of a foreign company to be listed and may allow dual listing, su ...
itself from the Paris exchange to raise capital privately through traditional
private equity fund A private equity fund (abbreviated as PE fund) is a collective investment scheme used for making investments in various equity (and to a lesser extent debt) securities according to one of the investment strategies associated with private equity ...
s. Prior to the 1997 reorganization, Sofinnova Ventures raised three venture funds totaling $57M, and Sofinnova Partners raised funds with €85M in commitments. * 1997 - The global Sofinnova organization restructured, formally creating two separate management companies, one for Sofinnova Ventures, and one for Sofinnova Partners. The reorganization was done on the basis of geography, creating Sofinnova Ventures in the US and Sofinnova Partners in Europe. Following a
management buyout A management buyout (MBO) is a form of acquisition in which a company's existing managers acquire a large part, or all, of the company, whether from a parent company or individual. Management-, and/or leveraged buyout became noted phenomena of 1 ...
, each of the management companies was solely owned by its respective management teams.


2000s: The Move to Life Science for Sofinnova

* 2000 - Sofinnova Ventures hires Jim Healy, MD, PhD and together he and Mike Powell, PhD rebuilt the Sofinnova Ventures LS brand, with focus on clinical stage
drug development Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for re ...
companies. * 2003 - Sofinnova Ventures started its EIR/Executive Partner program in Life Sciences, with its first EIR Barry Selick. Following this, several other EIRs/Executive Partners joined Sofinnova Ventures from then until 2015, including: Jeff Stein, David Kabakoff, Bill Ringo (Strategic Advisor), Goro Takeda, Jay Shepard, George Horner, Lars Ekman and Dan Welch. * 2006 - Sofinnova Ventures and Sofinnova Partners first sponsored the Sofinnova Biopharm Partnering Conference in Japan, headed up by Sofinnova's Goro Takeda. In 2014, the conference teamed up with
Biotechnology Industry Organization The Biotechnology Innovation Organization (BIO) is the largest advocacy association in the world representing the biotechnology industry. It was founded in 1993 as the Biotechnology Industry Organization, and changed its name to the Biotechnology ...
, making this the largest biopartnering meeting in Japan. * 2007 - SVP VII was raised, which was Sofinnova Ventures' first fund that was overwhelmingly focused on Life Science (80%+), with emphasis on drug development. Their next fund, SVP VIII in 2011 was exclusively (100%) Life Science. At the same time, Sofinnova Partners in Paris moved from a balanced IT/LS venture firm, to one that was predominantly focused on Life Science. * 2008 - Sofinnova Ventures made its last IT investment (Enovix). The remaining IT team was active for several years after this to monitor and monetize the final IT investments.


2010s: New Growth Initiatives at Sofinnova

* 2010 - Sofinnova Partners started their Green Seed Fund and hired Joško Bobanović to manage this new initiative. In 2012, this seed fund initiative was announced in conjunction with the Sofinnova Capital VII announcement. * 2013 - Sofinnova Ventures worked with General Partner Garheng Kong to spin out a new fund, called HealthQuest Capital. HQC's mandate is to provide growth capital to companies transforming healthcare, with a focus on companies other than drug development. HQC raised their second fund, at $225M, in 2016, and transitioned to further independence from the parent Sofinnova Ventures organization. * 2017 - Sofinnova Partners announced the first closing o
Sofinnova Industrial Biotech I
at €106 million. The fund, dedicated to renewable chemistry, follows a series of 9 investments in the sector since 2009.


References


Done Deals: Venture Capitalists Tell Their Stories
2000. p. 249-250
The New Venturers: Inside the High-stakes World of Venture Capital
1985. p. 117
Sofinnova SA Public Repurchase offering
(''French'')


Sofinnova Partners


Accent to Expand with Investment from Sofinnova Partners


Sofinnova Ventures


Sofinnova Ventures
Business Week Profile.
DISTILLATIONS
University of Toronto


External links


Sofinnova Ventures (US)
- company website
Sofinnova Partners (France)
- company website {{Authority control Financial services companies established in 1972 Companies based in San Francisco Venture capital firms of the United States Life sciences industry French companies established in 1972