Soulless may refer to:
*
Soulless (gene), a historic name for PHOX2A, a human transcription factor
*
''Soulless'' (film), a 2012 film
*
''Soulless'' (album), a 1994 album by metal band Grave
*
''Soulless'' (novel), a 2009 steampunk novel by Gail Carriger
** ''
Soulless: The Manga'', a manga-style graphic adaptation of the above-mentioned
*''
Soulless: Ann Coulter and the Right-Wing Church of Hate'', a 2006 book by Susan Estrich
*
"Soulless" (''Angel''), a 2003 episode of the television series ''Angel''
*
"Soulless" (''Law & Order Special Victims Unit''), a 2003 episode of the television series ''Law & Order: Special Victims Unit''
* A race of characters in the
Myth II: Soulblighter computer game
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