
Snail slime is a kind of
mucus
Mucus (, ) is a slippery aqueous secretion produced by, and covering, mucous membranes. It is typically produced from cells found in mucous glands, although it may also originate from mixed glands, which contain both Serous fluid, serous and muc ...
(an external bodily
secretion
Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland. In contrast, excretion is the removal of certain substances or waste products from a cell or organism. The classical mec ...
) produced by
snails
A snail is a shelled gastropod. The name is most often applied to land snails, terrestrial molluscs, terrestrial pulmonate gastropod molluscs. However, the common name ''snail'' is also used for most of the members of the molluscan class Gas ...
, which are
gastropod
Gastropods (), commonly known as slugs and snails, belong to a large Taxonomy (biology), taxonomic class of invertebrates within the phylum Mollusca called Gastropoda ().
This class comprises snails and slugs from saltwater, freshwater, and fro ...
mollusk
Mollusca is a phylum of protostomic invertebrate animals, whose members are known as molluscs or mollusks (). Around 76,000 extant species of molluscs are recognized, making it the second-largest animal phylum after Arthropoda. The ...
s.
Land snail
A land snail is any of the numerous species of snail that live on land, as opposed to the sea snails and freshwater snails. ''Land snail'' is the common name for terrestrial molluscs, terrestrial gastropod mollusks that have gastropod shell, shel ...
s and
slug
Slug, or land slug, is a common name for any apparently shell-less Terrestrial mollusc, terrestrial gastropod mollusc. The word ''slug'' is also often used as part of the common name of any gastropod mollusc that has no shell, a very reduced ...
s both produce mucus, as does every other kind of gastropod, from marine, freshwater, and terrestrial habitats. The
reproductive system of gastropods
The reproductive system of gastropods (slugs and snails) varies greatly from one group to another within this very large and diverse taxonomic class of animals. Their reproduction, reproductive strategies also vary greatly.
In many marine (ocean ...
also produces mucus internally from special glands.
Chemically, the mucus produced by land-living gastropodes belongs to the class of
glycosaminoglycan
Glycosaminoglycans (GAGs) or mucopolysaccharides are long, linear polysaccharides consisting of repeating disaccharide units (i.e. two-sugar units). The repeating two-sugar unit consists of a uronic sugar and an amino sugar, except in the case o ...
s (previously called mucopolysaccharides). Externally, one kind of mucus is produced by the foot of the gastropod and is usually used for crawling. The other kind of external mucus has evolved to coat the external parts of the gastropod's body; in land species, this coating helps prevent
desiccation
Desiccation is the state of extreme dryness, or the process of extreme drying. A desiccant is a hygroscopic (attracts and holds water) substance that induces or sustains such a state in its local vicinity in a moderately sealed container. The ...
of the exposed soft tissues. The foot mucus of a gastropod has some of the qualities of glue and some of the qualities of a
lubricant
A lubricant (sometimes shortened to lube) is a substance that helps to reduce friction between surfaces in mutual contact, which ultimately reduces the heat generated when the surfaces move. It may also have the function of transmitting forces, ...
, allowing land snails to crawl up vertical surfaces without falling off.
The slime trail that a land gastropod leaves behind is often visible as a silvery track on surfaces such as stone or concrete.
Description

Mucus is a
gel consisting of a
polymer
A polymer () is a chemical substance, substance or material that consists of very large molecules, or macromolecules, that are constituted by many repeat unit, repeating subunits derived from one or more species of monomers. Due to their br ...
network that functions as a protective layer for the
integument
In biology, an integument is the tissue surrounding an organism's body or an organ within, such as skin, a husk, Exoskeleton, shell, germ or Peel (fruit), rind.
Etymology
The term is derived from ''integumentum'', which is Latin for "a coverin ...
and mucosal surfaces of both elementary animals and mammals.
The mucus of
gastropod
Gastropods (), commonly known as slugs and snails, belong to a large Taxonomy (biology), taxonomic class of invertebrates within the phylum Mollusca called Gastropoda ().
This class comprises snails and slugs from saltwater, freshwater, and fro ...
s is not only used as a coating to cover the surfaces on which the snail crawls and a coating to cover the exposed soft parts of the body but also sometimes to allow a resting snail to adhere passively to surfaces, such as rock.
Gastropod mucus adhesion uses a temporary sealing structure called the
epiphragm. Mucus is produced by a
large gland located below the snail's mouth.
The foot of gastropods is covered with a thin layer of this mucus, which is used for a variety of functions, including locomotion, adherence, lubrication, repulsing predators, recognizing other snails, following a trail to a known destination and during reproduction. The discharge looks like a gel and it contains approximately 91 to 98% water by weight, depending on the species, combined with a small amount of high
molecular weight
A molecule is a group of two or more atoms that are held together by Force, attractive forces known as chemical bonds; depending on context, the term may or may not include ions that satisfy this criterion. In quantum physics, organic chemi ...
glycoprotein
Glycoproteins are proteins which contain oligosaccharide (sugar) chains covalently attached to amino acid side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known a ...
s. In ''Cornu aspersum'', these glycoproteins reach weights of 82, 97 and 175
kDa.
Locomotion
Locomotion in snails comes from a series of muscle contractions called
pedal waves and relaxations called inter waves. The waves created help propel the snail forward whilst pushing the thin layer of mucus used as lubrication, behind them. In an
Experimental Biology' article, research has been presented showing that each wave is indeed creating a propulsive force using the mucus to reduce resistance.
Land mollusks travel by
adhesive locomotion via muscular waves that propagate from tail to head. The snail mucus has an adapted
flow behavior that allows transmittance of the muscular force while maintaining
adhesion
Adhesion is the tendency of dissimilar particles or interface (matter), surfaces to cling to one another. (Cohesion (chemistry), Cohesion refers to the tendency of similar or identical particles and surfaces to cling to one another.)
The ...
.
When inactive, many mollusks of both marine and terrestrial species, use the secretion to stick to various surfaces. However, although it is so diluted that it can commonly act as a lubricant, it can also have strong adhesive properties. In their unique mating ritual, ''
Limax maximus
''Limax maximus'' (literally, "biggest slug"), known by the common names great grey slug and leopard slug, is a species of slug in the family Limacidae, the keeled slugs.Marshall, B. (2014). Limax maximus Linnaeus, 1758. Accessed through: World ...
'' use a mucus thread to suspend themselves from elevated locations like tree branches.
In ''Cornu aspersum'', there are three types of secretion. One type is translucent and not adhesive, the kind that the snail leaves behind as it moves (the slime trail), another is similar but thicker, condensed, more
viscous
Viscosity is a measure of a fluid's rate-dependent resistance to a change in shape or to movement of its neighboring portions relative to one another. For liquids, it corresponds to the informal concept of ''thickness''; for example, syrup h ...
and elastic, which is used to adhere to various surfaces, and a third viscous coating on the dorsal surface that is a protective barrier.
Both are clearly differentiated by the type of proteins present in them.
Slime production
A snail releases different kinds of mucus depending on the way it is stimulated. When the stimulation is normal, the slime is viscous (sticky) but if the snail is disturbed continuously or even violently, it releases clear
foam
Foams are two-phase materials science, material systems where a gas is dispersed in a second, non-gaseous material, specifically, in which gas cells are enclosed by a distinct liquid or solid material. Note, this source focuses only on liquid ...
y secretions. If the snail is
sexually aroused the slime it releases is clear and viscous. In the case of ''
Cornu aspersum
''Cornu aspersum'' (syn. ''Helix aspersa'', ''Cryptomphalus aspersus''), known by the common name garden snail, is a species of land snail in the family Helicidae, which includes some of the most familiar land snails. Of all terrestrial molluscs, ...
'', the discharge is composed of synthesized products from various types of
secretory glands. These are all single-cell glands found in
connective tissue
Connective tissue is one of the four primary types of animal tissue, a group of cells that are similar in structure, along with epithelial tissue, muscle tissue, and nervous tissue. It develops mostly from the mesenchyme, derived from the mesod ...
and they secrete their products via pores that pass between the
epidermal cells. They are of various shapes and usually have a long excretory duct. There are eight different types of secreting glands. Four of these different types secrete
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
,
calcium
Calcium is a chemical element; it has symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar to it ...
,
pigment
A pigment is a powder used to add or alter color or change visual appearance. Pigments are completely or nearly solubility, insoluble and reactivity (chemistry), chemically unreactive in water or another medium; in contrast, dyes are colored sub ...
s and
lipid
Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids include storing ...
s.
Medical uses
Some of the characteristics of snail slime have shown to be useful in Chinese medicine.
Traditional Chinese medicine
Traditional Chinese medicine (TCM) is an alternative medicine, alternative medical practice drawn from traditional medicine in China. A large share of its claims are pseudoscientific, with the majority of treatments having no robust evidence ...
has used slime in a variety of ways to treat a variety of illnesses and cosmetic issues. It has also been used as skin creams for
wrinkles and
dry skin
Xeroderma, xerosis or xerosis cutis, or simply dry skin, is a skin condition characterized by excessively dry skin. The term derives .
In most cases, dry skin can safely be treated with moisturizers (also called emollients). Xeroderma occurs ...
in cosmetics. The Chinese also have used the color-fast dry qualities of snail slime as a
natural dye
Natural dyes are dyes or colorants derived from plants, invertebrates, or minerals. The majority of natural dyes are vegetable dyes from plant sources—roots, berry, berries, Bark (botany), bark, leaf, leaves, and wood—and other biological sourc ...
that represented wealth and power. The mucus has demonstrated several
biological activities including
antimicrobial
An antimicrobial is an agent that kills microorganisms (microbicide) or stops their growth (bacteriostatic agent). Antimicrobial medicines can be grouped according to the microorganisms they are used to treat. For example, antibiotics are used aga ...
,
antioxidant
Antioxidants are Chemical compound, compounds that inhibit Redox, oxidation, a chemical reaction that can produce Radical (chemistry), free radicals. Autoxidation leads to degradation of organic compounds, including living matter. Antioxidants ...
,
anti-tyrosinase, and
anti-tumoral activities.
A new generation of
tissue adhesive has been developed by using natural adhesion phenomena and mechanisms, such as snail mucus gel, which exhibits excellent
haemostatic activity,
biocompatibility
Biocompatibility is related to the behavior of biomaterials in various contexts. The term refers to the ability of a material to perform with an appropriate host response in a specific situation. The ambiguity of the term reflects the ongoin ...
, and
biodegradability. It is effective in accelerating the
healing
With physical trauma or disease suffered by an organism, healing involves the repairing of damaged tissue(s), organs and the biological system as a whole and resumption of (normal) functioning. Medicine includes the process by which the cells ...
of full-thickness skin wounds in both normal and diabetic male rats.
See also
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References
Further reading
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*{{cite journal , last1=Barajas-Ledesma , first1=Edgar , last2=Holland , first2=Chris , title=Probing the compositional and rheological properties of gastropod locomotive mucus , journal=Frontiers in Soft Matter , date=14 September 2023 , volume=3 , doi=10.3389/frsfm.2023.1201511 , doi-access=free , url=https://eprints.whiterose.ac.uk/203845/1/frsfm-03-1201511.pdf
Gastropod anatomy
Mollusc products