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Eggshell membrane or shell membrane is the clear film lining
eggshell An eggshell is the outer covering of a hard-shelled egg and of some forms of eggs with soft outer coats. Diversity Worm eggs Nematode eggs present a two layered structure: an external vitellin layer made of chitin that confers mechanical ...
s, visible when one peels a boiled bird egg. Chicken eggshell membranes are used as a
dietary supplement A dietary supplement is a manufactured product intended to supplement one's diet by taking a pill, capsule, tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources or that are synthetic in order ...
. Eggshell membrane is derived commercially from the eggshells of industrial processors. In the United States, egg-breaking facilities generate more than 24 billion broken eggshells every year. There are various ways in which the membrane is separated from the shell, including chemical, mechanical, steam, and vacuum processes.


Composition

Eggshell membrane is primarily composed of fibrous proteins such as
collagen Collagen () is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole ...
type I Type 1 or Type I or ''variant'', may refer to: Health *Diabetes mellitus type 1 (also known as "Type 1 Diabetes"), insulin-dependent diabetes * Type I female genital mutilation * Type 1 personality *Type I hypersensitivity (or immediate hypersensit ...
. Eggshell membranes also contain glycosaminoglycans, such as dermatan sulfate, chondroitin sulfate, and sulfated
glycoprotein Glycoproteins are proteins which contain oligosaccharide chains covalently attached to amino acid side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known as glycos ...
s including hexosamines, such as glucosamine. Other components identified in eggshell membranes are
hyaluronic acid Hyaluronic acid (; abbreviated HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans ...
,
sialic acid Sialic acids are a class of alpha-keto acid sugars with a nine-carbon backbone. The term "sialic acid" (from the Greek for saliva, - ''síalon'') was first introduced by Swedish biochemist Gunnar Blix in 1952. The most common member of this gr ...
, desmosine, isodesmosine, ovotransferrin, lysyl oxidase, lysozyme, and β-N-acetylglucosaminidase.


Uses

Shell membrane is mainly used as a dietary supplement in a partially
hydrolyzed Hydrolysis (; ) is any chemical reaction in which a molecule of water breaks one or more chemical bonds. The term is used broadly for substitution, elimination, and solvation reactions in which water is the nucleophile. Biological hydrolysis ...
powder form.


References

{{Authority control Eggs (food) Dietary supplements