Sergey Piletsky is a professor of

Bioanalytical Chemistry Bioanalysis is a sub-discipline of analytical chemistry covering the Quantitative analysis (chemistry), quantitative measurement of xenobiotics (drugs and their metabolites, and Biomolecule, biological molecules in unnatural locations or concentra ...

and the Research Director for School of Chemistry,

University of Leicester The University of Leicester ( ) is a public university, public research university based in Leicester, England. The main campus is south of the city centre, adjacent to Victoria Park, Leicester, Victoria Park. The university's predecessor, Univ ...

, United Kingdom.

Education

Sergey graduated from

Kyiv University The Taras Shevchenko National University of Kyiv (; also known as Kyiv University, Shevchenko University, or KNU) is a public university in Kyiv, Ukraine. The university is the third-oldest university in Ukraine after the University of Lviv and ...

, Ukraine, obtaining an MSc in chemistry in 1985 and researched on synthesis of the polymers selective for nucleic acids, for which he was awarded with a PhD in 1991.

Cranfield University Cranfield University is a postgraduate-only public research university in the United Kingdom that specialises in science, engineering, design, technology and management. Cranfield was founded as the College of Aeronautics (CoA) in 1946. Throug ...

awarded Sergey with a

DSc DSC or Dsc may refer to: Education * Doctor of Science (D.Sc.) * District Selection Committee, an entrance exam in India * Doctor of Surgical Chiropody, superseded in the 1960s by Doctor of Podiatric Medicine Educational institutions * Dyal Sin ...

for his work on

molecularly imprinted polymer A molecularly imprinted polymer (MIP) is a polymer that has been processed using the molecular imprinting technique which leaves cavities in the polymer matrix with an affinity for a chosen "template" molecule. The process usually involves initiati ...

s for diagnostics applications.

Awards

Sergey is a recipient of Royal Society Wolfson Research Merit Award, Leverhulme Trust Fellowship, DFG Fellowship from the Institute of Analytical Chemistry, Award of President of Ukraine, and Japan Society for Promotion of Science and Technology Fellowship.

Research

Sergey's work in molecular imprinting focuses on: (i) the fundamental study of the recognition properties of molecularly imprinted polymers; (ii) the development of

sensor A sensor is often defined as a device that receives and responds to a signal or stimulus. The stimulus is the quantity, property, or condition that is sensed and converted into electrical signal. In the broadest definition, a sensor is a devi ...

s and assays for environmental and clinical analysis; and (iii) the development of molecularly imprinted polymer

nanoparticle A nanoparticle or ultrafine particle is a particle of matter 1 to 100 nanometres (nm) in diameter. The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions. At ...

s for theranostic applications. Sergey introduced computational design into the field of molecular imprinting, by scientifically demonstrating that non-covalent interaction between the template molecule and polymer is through the technique known as 'bite and switch' wherein functional groups first non-covalently bond with the binding site, but during the rebinding step, the polymer matrix forms irreversible covalent bonds with the target molecule. A number of research groups around the world follow his ideas in developing functional imprinted polymers for a variety of applications.

Notable publications

* * * * Surface-grafted molecularly imprinted polymers for protein recognition, A Bossi, SA Piletsky, EV Piletska, PG Righetti, APF Turner, Analytical chemistry 73 (21), 5281-5286 * Electrochemical sensor for catechol and dopamine based on a catalytic molecularly imprinted polymer-conducting polymer hybrid recognition element, Dhana Lakshmi, Alessandra Bossi, Michael J Whitcombe, Iva Chianella, Steven A Fowler, Sreenath Subrahmanyam, Elena V Piletska, Sergey A Piletsky, Analytical Chemistry 81 (9), 3576-3584 * * * * * Piletsky S.A., Turner A.P.F. (2006). New generation of chemical sensors based on molecularly imprinted polymers, in: Molecular imprinting of polymers, S. Piletsky and A.P.F. Turner (eds.), Landes Bioscience, Georgetown, TX, USA

Notable patents

* Rationally Designed Selective Binding Polymers (2010), Publication number: 20100009859, Inventors: Sergey A. Piletsky, Olena Piletska, Khalku Karim, Coulton H. Legge, Sreenath Subrahmanyam * Electrochemical Sensor (2019) Publication number: 20210239643, Inventors: Sergey Piletsky, Omar Sheej Ahamad, Alvaro Garcia Cruz * Polymerisation method, polymers and uses thereof (2006) Publication number: 20060122288, Inventors: Sergey Piletsky, Olena Piletska, Anthony Turner, Khalku Karim, Beining Chen * Methods and Kits for determining binding sites (2020) Publication number: 20200033356, Inventors: Sergey Piletsky, Elena Piletska, Francesco Canfarotta, Don Jones * Photoreactor and Process for Preparing MIP Nanoparticles (2014) Publication number: 20140228472, Inventors: Sergey Piletsky, Olena Piletska, Antonio Guerreiro, Michael Whitcombe, Alessandro Poma

References

External links

* {{Authority control Year of birth missing (living people) Living people British chemists Alumni of Cranfield University British inventors Molecular modelling Computational biology Computational chemistry Biosensors Receptors Biomimetics Sensors Bioinorganic chemistry Ukrainian expatriates in England Ukrainian chemists 21st-century Ukrainian scientists