Securinine is an
alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids.
Alkaloids are produced by a large varie ...
found in ''
Securinega suffruticosa''
and ''
Phyllanthus niruri''.
Pharmacology
Securinine has pro-convulsant effects and it has a strong
spastic effect, similar to the actions of
strychnine
Strychnine (, , American English, US chiefly ) is a highly toxicity, toxic, colorless, bitter, crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents. Strychnine, when inhaled, swallowed, ...
.
Securinine is a GABA-
A antagonist.
See also
*
Norsecurinine
*
Phenazine
Phenazine is an organic compound with the formula (C6H4)2N2. It is a dibenzo annulation, annulated pyrazine, and the parent substance of many dyestuffs, such as the toluylene red, indulines, and safranines (and the closely related eurhodines). Phe ...
References
{{Reflist
Tetracyclic compounds
Nitrogen heterocycles
Lactones
Indolizidine alkaloids
Furanones
Heterocyclic compounds with 4 rings
Withdrawn drugs