SB-204741 is a drug which acts as a potent and selective

antagonist An antagonist is a character in a story who is presented as the main enemy or rival of the protagonist and is often depicted as a villain.serotonin Serotonin (), also known as 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter with a wide range of functions in both the central nervous system (CNS) and also peripheral tissues. It is involved in mood, cognition, reward, learning, ...

5-HT_2B

receptor Receptor may refer to: * Sensory receptor, in physiology, any neurite structure that, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and respond ...

, with around 135x selectivity over the closely related 5-HT_2C receptor, and even higher over the 5-HT_2A receptor and other targets. It is used in scientific research for investigating the functions of the 5-HT_2B receptor.

References

5-HT2B antagonists Isothiazoles Ureas Indoles {{nervous-system-drug-stub