RuvB-like 1 (E. coli), also known as RUVBL1 and TIP49, is a human
gene. RUVBL1 can form a hexamer. The hexamer can form a dodecamer with
RUVBL2
RuvB-like 2 (E. coli), also known as RUVBL2, is a human gene coding for a protein belonging to the AAA+ family of proteins.
Function
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helic ...
protein.
Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.
Interactions
RuvB-like 1 has been shown to
interact
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with:
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ACTL6A,
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Beta-catenin,
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EP400,
[
* Myc,]RUVBL2
RuvB-like 2 (E. coli), also known as RUVBL2, is a human gene coding for a protein belonging to the AAA+ family of proteins.
Function
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helic ...
.
References
Further reading
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