enzymology An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...

, a pyrimidine-5'-nucleotide nucleosidase () is an

enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...

that

catalyzes Catalysis () is the increase in rate of a chemical reaction due to an added substance known as a catalyst (). Catalysts are not consumed by the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quick ...

the

chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...

:a pyrimidine 5'-nucleotide + H₂O

\rightleftharpoons

D-ribose 5-phosphate + a pyrimidine base Thus, the two substrates of this enzyme are pyrimidine 5'-nucleotide and H₂O, whereas its two

products Product may refer to: Business * Product (business), an item that can be offered to a market to satisfy the desire or need of a customer. * Product (project management), a deliverable or set of deliverables that contribute to a business solution ...

are

D-ribose 5-phosphate Ribose 5-phosphate (R5P) is both a product and an intermediate of the pentose phosphate pathway. The last step of the Redox, oxidative reactions in the pentose phosphate pathway is the production of ribulose 5-phosphate. Depending on the body's s ...

and pyrimidine base. This enzyme belongs to the family of

hydrolase In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond: :\ce \quad \xrightarrowtext\quad \ce This typically results in dividing a larger molecule into s ...

s, specifically those glycosylases that hydrolyse N-glycosyl compounds. The

systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ...

of this enzyme class is pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase. Other names in common use include pyrimidine nucleotide N-ribosidase, and Pyr5N. This enzyme participates in

pyrimidine metabolism Pyrimidine biosynthesis occurs both in the body and through organic synthesis. ''De novo'' biosynthesis of pyrimidine ''De Novo'' biosynthesis of a pyrimidine is catalyzed by three gene products CAD, DHODH and UMPS. The first three enzymes of ...

References

* * EC 3.2.2 Enzymes of unknown structure {{3.2-enzyme-stub