''Principles of Neural Science'' is a
neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, ...
textbook
A textbook is a book containing a comprehensive compilation of content in a branch of study with the intention of explaining it. Textbooks are produced to meet the needs of educators, usually at educational institutions, but also of learners ( ...
edited by
Columbia University
Columbia University in the City of New York, commonly referred to as Columbia University, is a Private university, private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Churc ...
professors
Eric R. Kandel,
James H. Schwartz, and
Thomas M. Jessell. First published in 1981 by
McGraw-Hill
McGraw Hill is an American education science company that provides educational content, software, and services for students and educators across various levels—from K-12 to higher education and professional settings. They produce textbooks, ...
, the original edition was 468 pages, and has now grown to 1646 pages on the sixth edition. The second edition was published in 1985, third in 1991, fourth in 2000. The fifth was published on October 26, 2012 and included Steven A. Siegelbaum and A.J. Hudspeth as editors. The sixth and latest edition was published on March 8, 2021.
Authors
Editors
* Kandel was one of the recipients of the
2000
2000 was designated as the International Year for the Culture of Peace and the World Mathematics, Mathematical Year.
Popular culture holds the year 2000 as the first year of the 21st century and the 3rd millennium, because of a tende ...
Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine () is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, acco ...
. He is currently a professor of biochemistry, molecular biophysics, physiology, cellular biophysics, and psychiatry at
Columbia University
Columbia University in the City of New York, commonly referred to as Columbia University, is a Private university, private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Churc ...
. He is a senior investigator at the
Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization headquartered in Chevy Chase, Maryland with additional facilities in Ashburn, Virginia. It was founded in 1953 by Howard Hughes, an American busin ...
and a recipient of the
National Medal of Science
The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral science, behavior ...
.
* Schwartz was a professor of physiology, cellular biophysics, neurology, and psychiatry at Columbia University.
* Jessell became an editor of the book starting from the third edition. He was a professor of biochemistry and molecular biophysics at Columbia University, and an investigator at the Howard Hughes Medical Institute.
* Hudspeth is a professor of sensory neuroscience at
Rockefeller University
The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and pro ...
. He is also an investigator at the Howard Hughes Medical Institute.
* Siegelbaum is Chair of the Department of Neuroscience at Columbia University and is also an investigator at the Howard Hughes Medical Institute.
Contributors
Including the editors—all of whom also contributed to individual chapters in the book—there are a total of 45 authors of this text. Included among them are several notable researchers and physicians. Several authors are also highly decorated scientists, including
Nobel laureate
The Nobel Prizes (, ) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make outstanding contributions in th ...
Linda B. Buck and renowned neurophysiologist
Roger M. Enoka.
Content
''Principles of Neural Science'' is often assigned as a textbook for many
undergraduate
Undergraduate education is education conducted after secondary education and before postgraduate education, usually in a college or university. It typically includes all postsecondary programs up to the level of a bachelor's degree. For example, ...
and
graduate/
medical
Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
neuroscience and neurobiology courses. The book attempts to introduce every aspect of the most modern understanding of the
brain
The brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for ...
. The sixth edition is divided into sixty-four chapters, organized into nine parts:
* Part I: ''Overall Perspective''
* Part II: ''
Cell and
Molecular Biology
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactio ...
of Cells of the
Nervous System
In biology, the nervous system is the complex system, highly complex part of an animal that coordinates its behavior, actions and sense, sensory information by transmitting action potential, signals to and from different parts of its body. Th ...
''
* Part III: ''
Synaptic Transmission
Neurotransmission (Latin: ''transmissio'' "passage, crossing" from ''transmittere'' "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron) ...
''
* Part IV: ''
Perception
Perception () is the organization, identification, and interpretation of sensory information in order to represent and understand the presented information or environment. All perception involves signals that go through the nervous syste ...
''
* Part V: ''
Movement''
* Part VI: ''The Biology of
Emotion
Emotions are physical and mental states brought on by neurophysiology, neurophysiological changes, variously associated with thoughts, feelings, behavior, behavioral responses, and a degree of pleasure or suffering, displeasure. There is ...
,
Motivation
Motivation is an mental state, internal state that propels individuals to engage in goal-directed behavior. It is often understood as a force that explains why people or animals initiate, continue, or terminate a certain behavior at a particul ...
, and
Homeostasis
In biology, homeostasis (British English, British also homoeostasis; ) is the state of steady internal physics, physical and chemistry, chemical conditions maintained by organism, living systems. This is the condition of optimal functioning fo ...
''
* Part VII: ''
Development
Development or developing may refer to:
Arts
*Development (music), the process by which thematic material is reshaped
* Photographic development
*Filmmaking, development phase, including finance and budgeting
* Development hell, when a proje ...
and the Emergence of
Behavior
Behavior (American English) or behaviour (British English) is the range of actions of Individual, individuals, organisms, systems or Artificial intelligence, artificial entities in some environment. These systems can include other systems or or ...
''
* Part VIII: ''
Learning
Learning is the process of acquiring new understanding, knowledge, behaviors, skills, value (personal and cultural), values, Attitude (psychology), attitudes, and preferences. The ability to learn is possessed by humans, non-human animals, and ...
,
Memory
Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed. It is the retention of information over time for the purpose of influencing future action. If past events could not be remembe ...
,
Language
Language is a structured system of communication that consists of grammar and vocabulary. It is the primary means by which humans convey meaning, both in spoken and signed language, signed forms, and may also be conveyed through writing syste ...
and
Cognition
Cognition is the "mental action or process of acquiring knowledge and understanding through thought, experience, and the senses". It encompasses all aspects of intellectual functions and processes such as: perception, attention, thought, ...
''
* Part IX: ''
Diseases of the Nervous System''
References
Sources
* Kandel ER, Schwartz JH, Jessell TM 1991. ''Principles of Neural Science, 3rd ed.'' Appleton & Lange.
* Kandel ER, Schwartz JH, Jessell TM 2000. ''Principles of Neural Science, 4th ed.'' McGraw-Hill, New York.
* Kandel ER, Schwartz JH, Jessell TM 2012, Siegelbaum SA, Hudspeth AJ. ''Principles of Neural Science, 5th ed.'' McGraw-Hill, New York.
* Kandel ER, Koester JD, Mack SH 2021, Siegelbaum SA. ''Principles of Neural Science, 6th ed.'' McGraw-Hill, New York. ISBN 978-1-25-964224-1
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Neuroscience books
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