Pharmacia was a
pharmaceutical
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the medical field and ...
and
biotechnological company in
Sweden that merged with the
American pharmaceutical company
Upjohn in 1995.
History
Pharmacia company was founded in 1911 in
Stockholm, Sweden by pharmacist Gustav Felix Grönfeldt at the ''Elgen'' Pharmacy. The company is named after the Greek word φαρμακεία, transliterated ''pharmakeia'', which means 'sorcery'. In the company's early days, much of its profits were derived from the "miracle medicine"
Phospho-Energon.
During
World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the World War II by country, vast majority of the world's countries—including all of the great power ...
, Swedish chemist Björn Ingelman (who worked for
Arne Tiselius at
Uppsala university
Uppsala University ( sv, Uppsala universitet) is a public research university in Uppsala, Sweden. Founded in 1477, it is the oldest university in Sweden and the Nordic countries still in operation.
The university rose to significance durin ...
) researched various uses for the
polysaccharide
Polysaccharides (), or polycarbohydrates, are the most abundant carbohydrates found in food. They are long chain polymeric carbohydrates composed of monosaccharide units bound together by glycosidic linkages. This carbohydrate can react with ...
dextran. Together with the medical researcher Anders Grönwall, he discovered that dextran could be used as a replacement for
blood plasma
Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but contains proteins and other constituents of whole blood in suspension. It makes up about 55% of the body's total blood volume. It is the ...
in
blood transfusions
Blood transfusion is the process of transferring blood products into a person's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but m ...
, for which there could be a large need in wartime. Pharmacia, which then was still a small company, was contacted in 1943 and its CEO Elis Göth was very interested. The product Macrodex, a dextran solution, was launched four years later.
Dextran-based products were to play a significant role in the further expansion of Pharmacia. In 1951, the company moved to
Uppsala
Uppsala (, or all ending in , ; archaically spelled ''Upsala'') is the county seat of Uppsala County and the List of urban areas in Sweden by population, fourth-largest city in Sweden, after Stockholm, Gothenburg, and Malmö. It had 177,074 inha ...
, Sweden, to get closer to the scientists with whom they cooperated, and Ingelman became its head of research. In 1959, Pharmacia pioneered
gel filtration with its
Sephadex products. These were also based on dextran and discoveries in Tiselius' department, this time by
Jerker Porath and Per Flodin. In 1967 Pharmacia Fine Chemicals was established in Uppsala. In 1986 Pharmacia Fine Chemicals acquired LKB-produkter AB and changed name to Pharmacia Biotech. Pharmacia Biotech expanded their role in the "biotech revolution" through its acquisition of PL Laboratories from Pabst Brewery offering a line of recombinant DNA specialty research chemicals. Sold to private interests in the 1990s, Pharmacia was first merged with "Kabi Vitrum" to form Kabi Pharmacia with headquarters in Uppsala. In 1993, Kabi Pharmacia bought
Farmitalia, an Italian company that had developed
doxorubicin, a chemotherapeutic.
[Staff]
News: Farmitalia bought by Kabi Pharmacia
. Ann Oncol (1993) 4 (5): 345.
In 1995 the company merged with the
American pharmaceutical company
Upjohn, becoming known as
Pharmacia & Upjohn and moved its headquarters to
London
London is the capital and List of urban areas in the United Kingdom, largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary dow ...
.
In 1998, the company was divided into two business area. The pharmaceutical business became Pharmacia & Upjohn. The scientific instruments groups which sold chromatography resin, purification equipment, molecular biology reagents and electrophoresis products was purchased by
Amersham in 1998 and was named Amersham Pharmacia Biotech. They later changed the name to Amersham Biosciences and ran their radiochemical and reagents business along with the highly profitable chromatography business. The Pharmacia Logo Drop remained as a highly recognized brand. Amersham Biosciences was sold to GE Healthcare in April 1998 to become GE Healthcare Life Sciences. From 1 April 2020, GE Healthcare Life Sciences has been renamed in
Cytiva, following the sale of GE Healthcare Life Sciences from
General Electric
General Electric Company (GE) is an American multinational conglomerate founded in 1892, and incorporated in New York state and headquartered in Boston. The company operated in sectors including healthcare, aviation, power, renewable energ ...
to
Danaher Corporation
Danaher Corporation is an American globally diversified conglomerate with its headquarters in Washington, D.C. The company designs, manufactures, and markets professional, medical, industrial, and commercial products and services. The company' ...
in a $21.4 billion acquisition.
Overview
The following is an illustration of the company's mergers, acquisitions,
spin-offs and historical predecessors:
References
External links
Cytiva
{{Authority control
Pharmaceutical companies of Sweden
Biotechnology companies of Sweden
Defunct companies of Sweden
Pfizer
Pharmaceutical companies established in 1911
Pharmaceutical companies disestablished in 2002
Life sciences industry
Biotechnology companies disestablished in 2002
Uppsala
Swedish companies established in 1911
Swedish companies disestablished in 2002