DNA polymerase epsilon subunit 2 is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that in humans is encoded by the ''POLE2''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Interactions
POLE2 has been shown to
interact with
SAP18
Histone deacetylase complex subunit SAP18 is an enzyme that in humans is encoded by the ''SAP18'' gene.
Function
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Multisubunit complexes catalyze histone acet ...
.
References
Further reading
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External links
PDBe-KBprovides an overview of all the structure information available in the PDB for Human DNA polymerase epsilon subunit 2 (POLE2)
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