Notre Dame High School (Cape Girardeau, Missouri)
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Notre Dame Regional High School is a private
Roman Catholic The Catholic Church (), also known as the Roman Catholic Church, is the largest Christian church, with 1.27 to 1.41 billion baptized Catholics worldwide as of 2025. It is among the world's oldest and largest international institut ...
high school A secondary school, high school, or senior school, is an institution that provides secondary education. Some secondary schools provide both ''lower secondary education'' (ages 11 to 14) and ''upper secondary education'' (ages 14 to 18), i.e., ...
located in
Cape Girardeau Cape Girardeau ( , ; colloquially referred to as "Cape") is a city in Cape Girardeau and Scott Counties in the U.S. state of Missouri. At the 2020 census, the population was 39,540, making it the 17th-largest in the state. The city is one o ...
,
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. The school enrolls students in grades 9–12, and belongs to the Diocese of Springfield-Cape Girardeau. Notre Dame serves students from several communities in southeast Missouri and as far as southern Illinois. Notre Dame has also served as host to several
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, including students from
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History

Boys & Girls Academies Before the founding of St. Mary High School, the Catholic youth of this area studied at the historic college of St. Vincent for boys and the Loretto Academy for girls. St. Vincent's College was conducted by the Vincentian Fathers and the Loretto Academy was conducted by the Sisters of Loretto. St. Mary High School The building which housed St. Mary High School was the first permanent location of St. Francis Hospital until 1914. In the spring of 1925, Very Reverend Eberhardt Pruente, V.F. purchased this building at Sprigg and William Streets for $21,000 and renovated it for use as St. Mary High School. On September 1, 1925, the school opened enrolling 7th and 8th grades, and first year high school students. Sister Mary Francis was the first teacher. In 1928 the school was accredited by the State of Missouri. The first class graduated June 9, 1929, with eight students. In 1931, the school nearly closed due to the Depression, but Mother Jolendis gave the Sisters permission to teach in the school "gratis". The school progressed through the 1930s and 1940s in spite of times of war. Cape Girardeau Catholic High School to Notre Dame High School This building served as St. Mary High School for twenty-nine years before its capacity could not accommodate the enlarging student body. In 1948, Rev. Theon Schoen, then pastor of St. Mary, began plans for a new and larger high school. Land was purchased between Caruthers and Clark Avenue from the Wulfers family for a new Catholic high school. A groundbreaking ceremony was held on June 21, 1953, for a new building that would accommodate between 350 and 400 students. The new Cape Girardeau Catholic High School opened on September 13, 1954, with an enrollment of 211 students. The school changed its name to Notre Dame High School in 1960. In 1962 Notre Dame received accreditation from the North Central Association of Secondary Schools and Colleges. Notre Dame Established as a Regional High School In 1995 it was determined that the building was no longer serving the needs of the school community, and a capital campaign began to construct a new high school off Route K. The new campus opened in August 1998 on land donated by the James and Wanda Drury Family Trust. The school was built to accommodate 600 students. The school was renamed Notre Dame Regional High School in conjunction with the school's broad enrollment. Today Notre Dame Regional High School is the largest private high school between St. Louis and Memphis. It has grown to an enrollment of over 500 students. Notre Dame Regional High School would not be where it is today without the dedicated School Sisters of Notre Dame and the Franciscan Brothers of Brooklyn.


Notes and references

{{authority control Roman Catholic Diocese of Springfield–Cape Girardeau High schools in Cape Girardeau County, Missouri Catholic secondary schools in Missouri Buildings and structures in Cape Girardeau, Missouri Educational institutions established in 1925 1925 establishments in Missouri