Mohamed Salem may refer to:
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Mohamed Salem (footballer, born 1940) (1940–2008), Algerian footballer
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Mohamed Salem (footballer, born 1994), Egyptian footballer
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Mohamed Salem (wrestler) (born 1944), Egyptian Olympic wrestler
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Mohamed Ben Salem (born 1953), Tunisian politician
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Mohamed Abd-el-Kader Salem, Egyptian academic and politician
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Mohamed Salem Al-Tunaiji (born 1969), Emirati middle-distance runner
{{hndis, Salem, Mohamed