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Merz Pharma GmbH & Co. KGaA (also ''Merz Pharma KGaA'' or ''Merz'') is an internationally active family-owned company, headquartered in
Frankfurt am Main Frankfurt am Main () is the most populous city in the States of Germany, German state of Hesse. Its 773,068 inhabitants as of 2022 make it the List of cities in Germany by population, fifth-most populous city in Germany. Located in the forela ...
,
Germany Germany, officially the Federal Republic of Germany, is a country in Central Europe. It lies between the Baltic Sea and the North Sea to the north and the Alps to the south. Its sixteen States of Germany, constituent states have a total popu ...
. Merz is the parent company of independent businesses in the fields of
aesthetic medicine Aesthetic medicine is a branch of modern medicine that focuses on altering natural or acquired unwanted appearance through the treatment of conditions including scars, skin laxity, wrinkles, moles, liver spots, excess fat, cellulite, unwanted hair, ...
, therapeutic medicine (including for neurological movement disorders), and wellness and beauty products with its brands Tetesept and Merz Spezial.


Company Structure

The company was founded by Friedrich Merz and is still family-owned.Einecke, Helga (2013-04-04). "Merz hautnah". ''Süddeutsche'' ''Zeitung'' (in German). Retrieved 2023-05-17. The management consists of Philip Burchard and Hans-Jörg Bergler. Merz Pharma GmbH & Co. KGaA is the parent company of the Merz Group. Since the 2020/21 financial year, the group has controlled the three businesses Merz Aesthetics GmbH, Merz Therapeutics GmbH and Merz Consumer Care GmbH. The businesses are under the supervision of the Merz board of partners and the Merz supervisory board.Merz Pharma GmbH & Co. KGaA (2022-07-27). "Konzernabschluss zum Geschäftsjahr vom 01.07.2020 bis zum 30.06.2021". '' Bundesanzeiger'' (in German). Retrieved 2023-05-17. Merz employs around 3,730 people (2021/22) and generated a revenue of EUR 1.3434 billion in the 2021/22 fiscal year. A large part of the revenue is generated in the United States through the sale of special products for medical and aesthetic applications.Oppenkowski, Detmar (2020-10-14). "Schöhnheit für Hollywood". ''
Mitteldeutsche Zeitung The ''Mitteldeutsche Zeitung'' (; ) is a regional daily newspaper for southern Saxony-Anhalt, Germany. Published in Halle, Saxony-Anhalt, Halle with several local versions, the paper is owned by M. DuMont Schauberg, Cologne. History and profile ...
'' (in German). Retrieved 2023-05-17.
Approximately 45% of sales are generated in the United States and almost 80% of all sales are generated outside of Germany.


Production sites and subsidiaries

Merz manages three production sites in Reinheim and
Dessau Dessau is a district of the independent city of Dessau-Roßlau in Saxony-Anhalt at the confluence of the rivers Mulde and Elbe, in the ''States of Germany, Bundesland'' (Federal State) of Saxony-Anhalt. Until 1 July 2007, it was an independent ...
(Germany) as well as in
Racine County, Wisconsin Racine County ( ) is a County (United States), county in southeastern Wisconsin. As of the 2020 United States census, 2020 census, its population was 197,727, making it Wisconsin's fifth-most populous county. Its county seat is Racine, Wisconsi ...
(
USA The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 states and a federal capital district, Washington, D.C. The 48 contiguous ...
).Bürkmann, Silvia (2013-06-28). "Leuchtturm blinkt in alle Welt". ''
Mitteldeutsche Zeitung The ''Mitteldeutsche Zeitung'' (; ) is a regional daily newspaper for southern Saxony-Anhalt, Germany. Published in Halle, Saxony-Anhalt, Halle with several local versions, the paper is owned by M. DuMont Schauberg, Cologne. History and profile ...
'' (in German). Retrieved 2023-05-17.
In addition, the Group has its own sales offices in
Brazil Brazil, officially the Federative Republic of Brazil, is the largest country in South America. It is the world's List of countries and dependencies by area, fifth-largest country by area and the List of countries and dependencies by population ...
,
France France, officially the French Republic, is a country located primarily in Western Europe. Overseas France, Its overseas regions and territories include French Guiana in South America, Saint Pierre and Miquelon in the Atlantic Ocean#North Atlan ...
,
Great Britain Great Britain is an island in the North Atlantic Ocean off the north-west coast of continental Europe, consisting of the countries England, Scotland, and Wales. With an area of , it is the largest of the British Isles, the List of European ...
,
Italy Italy, officially the Italian Republic, is a country in Southern Europe, Southern and Western Europe, Western Europe. It consists of Italian Peninsula, a peninsula that extends into the Mediterranean Sea, with the Alps on its northern land b ...
,
Canada Canada is a country in North America. Its Provinces and territories of Canada, ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, making it the world's List of coun ...
,
South Korea South Korea, officially the Republic of Korea (ROK), is a country in East Asia. It constitutes the southern half of the Korea, Korean Peninsula and borders North Korea along the Korean Demilitarized Zone, with the Yellow Sea to the west and t ...
,
Mexico Mexico, officially the United Mexican States, is a country in North America. It is the northernmost country in Latin America, and borders the United States to the north, and Guatemala and Belize to the southeast; while having maritime boundar ...
,
Austria Austria, formally the Republic of Austria, is a landlocked country in Central Europe, lying in the Eastern Alps. It is a federation of nine Federal states of Austria, states, of which the capital Vienna is the List of largest cities in Aust ...
,
Russia Russia, or the Russian Federation, is a country spanning Eastern Europe and North Asia. It is the list of countries and dependencies by area, largest country in the world, and extends across Time in Russia, eleven time zones, sharing Borders ...
,
Switzerland Switzerland, officially the Swiss Confederation, is a landlocked country located in west-central Europe. It is bordered by Italy to the south, France to the west, Germany to the north, and Austria and Liechtenstein to the east. Switzerland ...
,
Singapore Singapore, officially the Republic of Singapore, is an island country and city-state in Southeast Asia. The country's territory comprises one main island, 63 satellite islands and islets, and one outlying islet. It is about one degree ...
,
Spain Spain, or the Kingdom of Spain, is a country in Southern Europe, Southern and Western Europe with territories in North Africa. Featuring the Punta de Tarifa, southernmost point of continental Europe, it is the largest country in Southern Eur ...
,
Taiwan Taiwan, officially the Republic of China (ROC), is a country in East Asia. The main geography of Taiwan, island of Taiwan, also known as ''Formosa'', lies between the East China Sea, East and South China Seas in the northwestern Pacific Ocea ...
, USA,
Argentina Argentina, officially the Argentine Republic, is a country in the southern half of South America. It covers an area of , making it the List of South American countries by area, second-largest country in South America after Brazil, the fourt ...
,
Australia Australia, officially the Commonwealth of Australia, is a country comprising mainland Australia, the mainland of the Australia (continent), Australian continent, the island of Tasmania and list of islands of Australia, numerous smaller isl ...
,
China China, officially the People's Republic of China (PRC), is a country in East Asia. With population of China, a population exceeding 1.4 billion, it is the list of countries by population (United Nations), second-most populous country after ...
,
Hong Kong Hong Kong)., Legally Hong Kong, China in international treaties and organizations. is a special administrative region of China. With 7.5 million residents in a territory, Hong Kong is the fourth most densely populated region in the wor ...
,
India India, officially the Republic of India, is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area; the List of countries by population (United Nations), most populous country since ...
,
Indonesia Indonesia, officially the Republic of Indonesia, is a country in Southeast Asia and Oceania, between the Indian Ocean, Indian and Pacific Ocean, Pacific oceans. Comprising over List of islands of Indonesia, 17,000 islands, including Sumatra, ...
,
Colombia Colombia, officially the Republic of Colombia, is a country primarily located in South America with Insular region of Colombia, insular regions in North America. The Colombian mainland is bordered by the Caribbean Sea to the north, Venezuel ...
, the
Netherlands , Terminology of the Low Countries, informally Holland, is a country in Northwestern Europe, with Caribbean Netherlands, overseas territories in the Caribbean. It is the largest of the four constituent countries of the Kingdom of the Nether ...
,
Thailand Thailand, officially the Kingdom of Thailand and historically known as Siam (the official name until 1939), is a country in Southeast Asia on the Mainland Southeast Asia, Indochinese Peninsula. With a population of almost 66 million, it spa ...
,
Malaysia Malaysia is a country in Southeast Asia. Featuring the Tanjung Piai, southernmost point of continental Eurasia, it is a federation, federal constitutional monarchy consisting of States and federal territories of Malaysia, 13 states and thre ...
, the
Philippines The Philippines, officially the Republic of the Philippines, is an Archipelagic state, archipelagic country in Southeast Asia. Located in the western Pacific Ocean, it consists of List of islands of the Philippines, 7,641 islands, with a tot ...
, the
United Arab Emirates The United Arab Emirates (UAE), or simply the Emirates, is a country in West Asia, in the Middle East, at the eastern end of the Arabian Peninsula. It is a Federal monarchy, federal elective monarchy made up of Emirates of the United Arab E ...
and
Vietnam Vietnam, officially the Socialist Republic of Vietnam (SRV), is a country at the eastern edge of mainland Southeast Asia, with an area of about and a population of over 100 million, making it the world's List of countries and depende ...
. In addition, the group is active in around 70 countries through cooperations and distribution partnerships.


Business Activities


Merz Aesthetics

Merz Aesthetics develops and sells products in the field of aesthetic medicine, e.g. a
botulinum toxin Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium ''Clostridium botulinum'' and related species. It prevents the release of the neurotransmitter acetylcholine from axon en ...
, dermal fillers or medical technology. It is the world's largest company dedicated exclusively to medical aesthetics. Bob Rhatigan manages this business as CEO. Merz Aresthetics uses celebrities to market its products. In 2019, model
Christie Brinkley Christie Lee Brinkley (née Hudson; born February 2, 1954) is an American model. Brinkley appeared on an unprecedented three consecutive covers of ''Sports Illustrated'' Sports Illustrated Swimsuit Issue, Swimsuit Issues in 1979, 1980, and 1981 ...
promoted a non-invasive wrinkle-tightening procedure.
Gwyneth Paltrow Gwyneth Kate Paltrow ( ; born September 27, 1972) is an American actress and businesswoman. The daughter of filmmaker Bruce Paltrow and actress Blythe Danner, she established herself as a leading lady appearing in mainly mid-budget and perio ...
became the first brand ambassador for Merz Aesthetics in 2020. In 2023,
Christina Aguilera Christina María Aguilera ( , ; born December 18, 1980) is an American singer-songwriter, actress and television personality. Recognized as Cultural impact of Christina Aguilera, an influential figure in music and having received Public imag ...
promoted anti-wrinkle injections. The company is also primary sponsor for the
North Carolina Courage The North Carolina Courage are an American professional Association football, soccer team based in Cary, North Carolina, that competes in the National Women's Soccer League (NWSL). It was founded on January 9, 2017, after Stephen Malik acqui ...
. Merz announced its first three ambassadors for the Asia-Pacific region in 2022; Korean celebrities
Lee Min-ho Lee Min-ho (, born June 22, 1987) is a South Korean actor and singer. He gained widespread fame with his role as Gu Jun-pyo in the Korean drama, television series ''Boys Over Flowers (2009 TV series), Boys Over Flowers'' (2009), which also earn ...
,
Kim Ha-neul Kim Ha-neul (; born February 21, 1978) is a South Korean actress. After starting her career as a model, she rose to fame by starring in the films ''Ditto (2000 film), Ditto'' (2000), ''My Tutor Friend'' (2003), ''Too Beautiful to Lie'' (2004), ...
and Jeon So-min. In November 2024, the FDA reprimanded Merz for a misleading Instagram ad featuring Nate Berkus promoting Xeomin. The agency criticized claims about the drug’s rapid effects and unique benefits, citing a lack of supporting data, and found the risk disclosures inadequate, making the ad misleading about Xeomin’s safety.


Merz Therapeutics

Merz Therapeutics develops and distributes products for the treatment of neurological movement disorders such as
dystonia Dystonia is a neurology, neurological Hyperkinesia, hyperkinetic Movement disorders, movement disorder in which sustained or repetitive muscle contractions occur involuntarily, resulting in twisting and repetitive movements or abnormal fixed po ...
and
spasticity Spasticity () is a feature of altered skeletal muscle performance with a combination of paralysis, increased tendon reflex activity, and hypertonia. It is also colloquially referred to as an unusual "tightness", stiffness, or "pull" of muscles. ...
. It has its headquarters in Frankfurt. Stefan König has been the managing director of this division since 2023. In 2024, Merz Therapeutics acquired Inbrija, an inhaled Parkinson’s disease medication, and Ampyra (also known as Fampyra in some markets), a sustained-release multiple sclerosis tablet for $185 million from
Acorda Therapeutics Acorda Therapeutics, Inc. is an American biotechnology company based in Pearl River, New York. The company develops therapies that improve neurological function in people with Parkinson's disease, multiple sclerosis and other neurological disorde ...
, which had filed for bankruptcy.


Merz Consumer Care

Merz Consumer Care develops and distributes health, beauty, and wellness products. The main brands are tetesept and Merz Spezial. It has its headquarters in Frankfurt. Xenia Barth has been the managing director of this division since 2022. In May 2023, the name Merz Lifecare was introduced as the corporate brand instead of Merz Consumer Care. Merz Consumer Care GmbH has been retained as the company name.


History


Early days

In 1908, the trained pharmacist and chemist Friedrich Merz set up his own pharmaceutical production in Frankfurt am Main. At the time of its foundation, Merz already held a patent and a utility model protection. The company subsequently expanded and one year later moved to a former cigarette factory, where the company's headquarters have been located since. In the beginning, Merz developed and produced the first contraceptive for birth control, as well as menthol refreshment cigarettes, and ointments against scaly skin. During the
Second World War World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
, Allied air raids on Frankfurt destroyed about 70% of the buildings. However, Merz had outsourced duplicates of its production machinery to Reinheim (
Darmstadt Darmstadt () is a city in the States of Germany, state of Hesse in Germany, located in the southern part of the Frankfurt Rhine Main Area, Rhine-Main-Area (Frankfurt Metropolitan Region). Darmstadt has around 160,000 inhabitants, making it the ...
) and was thus able to quickly rebuild production after the end of the war.


Product Expansion

In 1953, Merz entered the cosmetics business with the first anti-wrinkle product (Placentubex). From the 1960s onwards, Merz developed dragées for beauty care. Merz Spezial Dragees came into the market in 1964 and were promoted in the 1970s and 1980s under the slogan "Natural beauty comes from within". In the 1970s, the company also expanded its products for medical prescription, for example for the treatment of
Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become ...
and lowering elevated blood lipids. In 2002, Merz developed
Memantine Memantine, sold under the brand name Namenda among others, is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. It is taken by mouth. Common side effects include headache, constipation, sleepiness, and dizz ...
, the world's first active ingredient for the treatment of moderate to severe Alzheimer's dementia. In 2005, Merz brought a new generation of botulinum toxins into the market. At that time, the preparation was the only botulinum toxin type A (BoNT/A) without complexing foreign proteins and thus reduced the risk of antibody-mediated therapy failure.


Change of Managing Director

In 2012, the previous managing director and grandson of the company founder, Jochen Hückmann, retired from the business and handed over the management to Burchard. Hückmann had held the management since the early 1970s. During this time, the company continued to expand its position internationally among other things with the development of the active ingredient Memantine.


Medical technology in the field of aesthetics

The
patent A patent is a type of intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an sufficiency of disclosure, enabling discl ...
for Memantine expired in Germany in 2012. Until then, it was the only approved drug against moderate and severe forms of dementia. In the USA, the drug still had three years of patent protection. In order not to suffer a drop in sales after the patent expired, the expansion of the aesthetic and special neurology divisions was pushed ahead. Three years earlier, Merz had acquired the US company Bioform Medical for EUR 190 million. Bioform specialised in the production of fillers for aesthetic medicine. This was followed in 2013 by the purchase of the Swiss company Neocutis, whose aesthetic dermatology products were mainly in the USA by physicians. In the same year Merz took over the Swiss company Anteis, which also produced fillers for aesthetic medicine. Merz entered the non-invasive facelift medical device business in 2014 with the acquisition of US company Ulthera for a sum close to $600 million. In 2015 Merz launched a subsidiary in
Thailand Thailand, officially the Kingdom of Thailand and historically known as Siam (the official name until 1939), is a country in Southeast Asia on the Mainland Southeast Asia, Indochinese Peninsula. With a population of almost 66 million, it spa ...
.


Creation of independent businesses

Merz established a new corporate structure in late 2020. This organisational structure consists of three independently operating business divisions: Merz Aesthetics, Merz Therapeutics and Merz Consumer Care. In addition, the global Merz Aesthetics team moved from Frankfurt to
Raleigh, North Carolina Raleigh ( ) is the List of capitals in the United States, capital city of the U.S. state of North Carolina. It is the List of municipalities in North Carolina, second-most populous city in the state (after Charlotte, North Carolina, Charlotte) ...
. In early 2020, the company's business collapsed for three months as a result of the initial impact of the
COVID-19 pandemic The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December ...
. Cosmetic and medical procedures were cancelled due to fear of contracting the virus and the scarcity of
personal protective equipment Personal protective equipment (PPE) is protective clothing, helmets, goggles, or other garments or equipment designed to protect the wearer's body from injury or infection. The hazards addressed by protective equipment include physical, elect ...
such as gloves. It was announced at the beginning of 2023 that Merz would invest around EUR 120 million in the Reinheim site and that production at the site between the old town and the Gersprenzauen meadows would be phased out.


References


External links


Merz Homepage
{{Authority control Manufacturing companies based in Frankfurt Pharmaceutical companies of Germany Pharmaceutical companies established in 1908 1908 establishments in Germany Medical and health organisations based in Hesse