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Marjorie Elizabeth Dulcie Bick (11 December 1915 – 18 October 2013) was an Australian biochemist.


Early life and education

Born the daughter of Charles William Bick of
Sandringham Sandringham can refer to: Places Australia * Sandringham, New South Wales, a suburb of Sydney * Sandringham, Queensland, a rural locality * Sandringham, Victoria, a suburb of Melbourne **Sandringham railway line **Sandringham railway station * ...
, Marjorie studied at Firbank Girl's Grammar School from 1920 and
matriculated Matriculation is the formal process of entering a university, or of becoming eligible to enter by fulfilling certain academic requirements such as a matriculation examination. Australia In Australia, the term ''matriculation'' is seldom used now ...
in 1932 to undertake a Bachelor of Science degree at the
University of Melbourne The University of Melbourne (colloquially known as Melbourne University) is a public university, public research university located in Melbourne, Australia. Founded in 1853, it is Australia's second oldest university and the oldest in the state ...
in 1937, then completed a Master of Science Degree at Melbourne in 1941.


Biochemist

Bick began her career as a biochemist at the
Walter and Eliza Hall Institute of Medical Research Walter may refer to: People and fictional characters * Walter (name), including a list of people and fictional and mythical characters with the given name or surname * Little Walter, American blues harmonica player Marion Walter Jacobs (1930–1 ...
, which beside the Commonwealth Serum Laboratories, was then one of the few institutions offering women in Australia the opportunity of a scientific career. She was amongst a number of notable biochemists, mostly women, like Beryl Splatt and Lorna Silvester who had a major influence on the nation's development of clinical biochemistry, She worked in the field of blood transfusion specialising in the production of
blood serum Serum () is the fluid and solvent component of blood which does not play a role in clotting. It may be defined as blood plasma without the clotting factors, or as blood with all cells and clotting factors removed. Serum contains all proteins ex ...
in the laboratory. In 1939, she was seconded to the Australian Red Cross Society (Victorian Division) Blood Transfusion Services. In 1940, she drove from Melbourne with Sheila Summons, Nancy Hayward and Kathleen Gilles to attend the Science Congress in Canberra where she discussed problems in blood transfusion with the Adelaide committee.


World War Two

Bick was invited to the USA and Canada with Dr Lucy Bryce to study developments in blood transfusion,  and worked at
Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
in the Plasma Fractionation Laboratory. Her research found a direct correlation between the platelet count of human blood, and its vasoconstrictor activity after clotting. Returning to Australia, she became biochemist to the Australian Red Cross Society, overseeing Victoria's Red Cross Blood Bank during WW2, during which she held the rank of captain in the
Australian Army Medical Corps The Royal Australian Army Medical Corps (RAAMC) is the branch of the Australian Army responsible for providing medical care to Army personnel. The AAMC was formed in 1902 through the amalgamation of medical units of the various Australian colon ...
. By 1944, she was Honorary Director of Training and Equipment at the Blood Bank in the
Royal Melbourne Hospital The Royal Melbourne Hospital (RMH), located in Parkville, Victoria, an inner suburb of Melbourne, is one of Australia's leading public hospitals. It is a major teaching hospital for tertiary health care with a reputation in clinical research. Th ...
and traveled again with Dr Bryce to study in America. They arrived on the ''S.S.'' ''Kanangoora'' in March 1945 and visited the Hooper Research Foundation in
Los Angeles Los Angeles, often referred to by its initials L.A., is the List of municipalities in California, most populous city in the U.S. state of California, and the commercial, Financial District, Los Angeles, financial, and Culture of Los Angeles, ...
then traveled to
New Orleans New Orleans (commonly known as NOLA or The Big Easy among other nicknames) is a Consolidated city-county, consolidated city-parish located along the Mississippi River in the U.S. state of Louisiana. With a population of 383,997 at the 2020 ...
and
Washington Washington most commonly refers to: * George Washington (1732–1799), the first president of the United States * Washington (state), a state in the Pacific Northwest of the United States * Washington, D.C., the capital of the United States ** A ...
, and attended a conference of the Blood Substitutes Committee of the National Research Council. Bryce then traveled to investigate clinical methods while Bick stayed on in Boston for eighteen months undertaking laboratory work on plasma fractionation in the Department of Physical Chemistry at
Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
under Professor Edwin J. Cohn, a pioneer in the field. She and Bryce reported on war conditions and attitudes to Australia in America and on the mass production methods at the
Cutter Laboratories Cutter Laboratories was a family-owned pharmaceutical company located in Berkeley, California, founded by Edward Ahern Cutter in 1897. Cutter's early products included anthrax vaccine, hog cholera (swine fever) virus, and anti-hog cholera serum� ...
of packing and shipping plasma and whole blood to be parachuted into the Pacific war zones. Their research coincided with a plan to expand the Blood Bank into a new floor of the Royal Melbourne Hospital.


Post-war career

In 1949, Bick concluded nine years of work for the Red Cross Blood Transfusion Service and joined the
Alfred Hospital The Alfred Hospital, (also known as The Alfred or Alfred Hospital) is a leading tertiary hospital in Melbourne, Victoria. It is the second oldest hospital in Victoria after Melbourne Hospital which is still operating on its original site. The ...
as a Senior Biochemist where she oversaw the management and implementation of new laboratory procedures at the Hospital. Recipient of a
Fulbright Scholarship The Fulbright Program, including the Fulbright–Hays Program, is one of several United States cultural exchange programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people ...
in 1955, she studied new techniques in the USA at the
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is a teaching hospital located in the West End neighborhood of Boston, Massachusetts. It is the original and largest clinical education and research facility of Harvard Medical School/Harvar ...
, Boston, and in the United Kingdom at the Isotope School of the Atomic Energy Commission and at
University College, London University College London (Trade name, branded as UCL) is a Public university, public research university in London, England. It is a Member institutions of the University of London, member institution of the Federal university, federal Uni ...
. Bick was a founding member and Victorian representative 1961–1963 of the Australasian Association of Clinical Biochemists (AACB) which was established 26 May 1961 during an
ANZAAS The Australian and New Zealand Association for the Advancement of Science (ANZAAS) is an organisation that was founded in 1888 as the Australasian Association for the Advancement of Science to promote science. It was modelled on the British ...
Congress in
Brisbane Brisbane ( ; ) is the List of Australian capital cities, capital and largest city of the States and territories of Australia, state of Queensland and the list of cities in Australia by population, third-most populous city in Australia, with a ...
. Bick then pursued her interest in environmental science and was awarded a Research Scholarship for research at the National Institute of Environmental Health in
North Carolina North Carolina ( ) is a U.S. state, state in the Southeastern United States, Southeastern region of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, South Carolina to the south, Georgia (U.S. stat ...
1967–1969, and then 1969–1971 worked as a biochemist at the Medical Research Council, Division of Clinical Chemistry, in the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotlan ...
, publishing on the effect of human exposure to pesticides and to hydrocarbons. Her analysis by
gas-liquid chromatography Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for Separation process, separating and analyzing compounds that can be vaporized without Chemical decomposition, decomposition. Typical uses of GC include t ...
of biopsy specimens of human body fat collected in 1965 from 53 individuals found DDT-derived material and dieldrin present in all samples; a mean concentration of total DDT equivalent stored was 1.81 ppm, and the mean concentration of dieldrin was 0.046 ppm. In other investigations she found that occupational exposure to
esterase In biochemistry, an esterase is a class of enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis (and as such, it is a type of hydrolase). A wide range of different esterases exist that differ ...
inhibitors used as pesticides in a group of orchardists, when spraying with reasonable care, is sufficient to cause a decrease in red-cell
acetylcholinesterase Acetylcholinesterase (HUGO Gene Nomenclature Committee, HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme th ...
activity. Bick returned to Australia in 1972 and worked in Pre-Clinical Drug Evaluation at the
Department of Health A health department or health ministry is a part of government which focuses on issues related to the general health of the citizenry. Subnational entities, such as states, counties and cities, often also operate a health department of their o ...
in
Canberra Canberra ( ; ) is the capital city of Australia. Founded following the Federation of Australia, federation of the colonies of Australia as the seat of government for the new nation, it is Australia's list of cities in Australia, largest in ...
and during the 1970s and 80s contributed to Drug Toxicity Evaluation at the
Therapeutic Goods Administration The Therapeutic Goods Administration (TGA) is the medicine and therapeutic regulatory agency of the Australian Government. As part of the Department of Health, Disability and Ageing, the TGA regulates the safety, quality, efficacy and advertisi ...
.


Personal life

In the 1950s, Bick was a member and secretary of the first all-women sailing club, The Victorian Ladies' Yacht Club. Retired in 1980, Bick ran a Victorian country Post Office and general store, later living in
Canberra Canberra ( ; ) is the capital city of Australia. Founded following the Federation of Australia, federation of the colonies of Australia as the seat of government for the new nation, it is Australia's list of cities in Australia, largest in ...
and then
Brighton Brighton ( ) is a seaside resort in the city status in the United Kingdom, city of Brighton and Hove, East Sussex, England, south of London. Archaeological evidence of settlement in the area dates back to the Bronze Age Britain, Bronze Age, R ...
. She died on 18 October 2013.


Publications

* * * * * * * * * * * * * * * *


References

{{DEFAULTSORT:Bick, Marjorie 1915 births 2013 deaths Australian biochemists Australian scientists Australian environmental scientists WEHI staff University of Melbourne alumni 20th-century Australian women scientists Military personnel from Melbourne Royal Australian Army Medical Corps officers Australian Army personnel of World War II Scientists from Melbourne