Malouetine is an
aminosteroid neuromuscular blocking agent and
antinicotinic alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids.
Alkaloids are produced by a large varie ...
isolated from ''
Malouetia'' spp.
The structure of malouetine inspired the development of modern aminosteroid muscle relaxants such as
pancuronium bromide and
vecuronium bromide
Vecuronium bromide, sold under the brand name Norcuron among others, is a medication used as part of general anesthesia to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is also used to help with endotracheal ...
by workers at
Organon
The ''Organon'' (, meaning "instrument, tool, organ") is the standard collection of Aristotle's six works on logical analysis and dialectic. The name ''Organon'' was given by Aristotle's followers, the Peripatetics, who maintained against the ...
.
References
Nicotinic antagonists
Steroidal alkaloids
Alkaloids found in Apocynaceae
Neuromuscular blockers
Quaternary ammonium compounds
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