Autologous cultured chondrocytes on porcine collagen membrane (Maci) is a
treatment to correct
cartilage
Cartilage is a resilient and smooth type of connective tissue. Semi-transparent and non-porous, it is usually covered by a tough and fibrous membrane called perichondrium. In tetrapods, it covers and protects the ends of long bones at the joints ...
defects in the knee.
It is used to treat symptomatic, full-thickness cartilage defects of the knee with or without bone involvement.
[ ] Autologous cultured chondrocytes on porcine collagen membrane is an autologous cellularized scaffold product.
This treatment is approved by the US Food and Drug Administration (FDA).
It is only administered to adults.
Healthy cartilage is removed from the person's own knees and a 'scaffold' is created on which the healthy tissue growths.
This is an
autologous matrix-induced chondrogenesis procedure which prevents tissue rejection complications since the transplanted cartilage comes from the same person.
Autologous cultured chondrocytes on porcine collagen membrane was approved for use in the United States in May 2019.
See also
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Microfracturing
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Knee osteoarthritis
In humans and other primates, the knee joins the thigh with the leg and consists of two joints: one between the femur and tibia (tibiofemoral joint), and one between the femur and patella (patellofemoral joint). It is the largest joint in the hu ...
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Knee pain
Knee pain is pain in or around the knee.
The knee joint consists of an articulation between four bones: the femur, tibia, fibula and patella. There are four compartments to the knee. These are the medial and lateral tibiofemoral compartments, the ...
References
Implants (medicine)
Orthopedic surgical procedures
Cartilage replacement therapy
Cell therapies
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