Loránd Kesztyűs ( Sarkad,

Hungary Hungary is a landlocked country in Central Europe. Spanning much of the Pannonian Basin, Carpathian Basin, it is bordered by Slovakia to the north, Ukraine to the northeast, Romania to the east and southeast, Serbia to the south, Croatia and ...

, 11 April 1915 −

Debrecen Debrecen ( ; ; ; ) is Hungary's cities of Hungary, second-largest city, after Budapest, the regional centre of the Northern Great Plain Regions of Hungary, region and the seat of Hajdú-Bihar County. A city with county rights, it was the large ...

, Hungary, 17 August 1979) was a Hungarian

physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...

, immunologist, pathophysiologist, a full member of the

Hungarian Academy of Sciences The Hungarian Academy of Sciences ( , MTA) is Hungary’s foremost and most prestigious learned society. Its headquarters are located along the banks of the Danube in Budapest, between Széchenyi rakpart and Akadémia utca. The Academy's primar ...

Career

He studied at the

University of Debrecen The University of Debrecen ( ) is a university located in Debrecen, Hungary. It is the oldest continuously operating institution of higher education in Hungary ever since its establishment in 1538. The university has a well established progra ...

until 1938, then worked at the Physiological and General Pathological Institute of the university. In 1948 he was appointed director of the Pathophysiological Institute of Debrecen, a post which he held until his death. During his directorship the institute became the research center of

immunology Immunology is a branch of biology and medicine that covers the study of Immune system, immune systems in all Organism, organisms. Immunology charts, measures, and contextualizes the Physiology, physiological functioning of the immune system in ...

in Hungary. Antibodies to muscle proteins were first prepared by Kesztyűs and his team; they also studied the reaction of these antibodies with the muscle protein antigens. During the early period of his career he studied - together with István Went -

antibodies An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as bacteria and viruses, including those that caus ...

and

flavins Flavins (from Latin ''flavus'', "yellow") refers generally to the class of organic compounds containing the tricyclic heterocycle isoalloxazine or its isomer alloxazine, and derivatives thereof. The biochemical source of flavin is the yellow B ...

, on the ground of their researches they could successfully produce immunizer

pharmaceutical drug Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the ...

s used as treatment for

allergies Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include Allergic rhinitis, hay fever, Food allergy, food al ...

. Later he investigated the relationship between

nervous system In biology, the nervous system is the complex system, highly complex part of an animal that coordinates its behavior, actions and sense, sensory information by transmitting action potential, signals to and from different parts of its body. Th ...

and

immunity Immunity may refer to: Medicine * Immunity (medical), resistance of an organism to infection or disease * ''Immunity'' (journal), a scientific journal published by Cell Press Biology * Immune system Engineering * Radiofrequence immunity ...

, and stated that despite the

neurological Neurology (from , "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the brain, the s ...

understanding being in force at that time the nervous system doesn't impact either on production of antibodies, or on

anaphylaxis Anaphylaxis (Greek: 'up' + 'guarding') is a serious, potentially fatal allergic reaction and medical emergency that is rapid in onset and requires immediate medical attention regardless of the use of emergency medication on site. It typicall ...

. He was a corresponding (1967), then a full member (1976) of the

, and the founder and first chairman of the Hungarian Immunological Society (1971).

Works

*''A kórélettan tankönyve.'' ectures on pathophysiology.Budapest, Medicina, 1963, 587 p. (With József Sós) *''Immunität und Nervensystem.'' Budapest, Akadémiai, 1967, 159 p. *''Kórélettan.'' athophysiology.Budapest, Medicina, 1975, 762 p.

References

*''A Magyar Tudományos Akadémia tagjai 1825–2002 II.'' embers of the Hungarian Academy of Sciences 1825–2002.Budapest, 2003, pp. 667. {{DEFAULTSORT:Kesztyus Lorand Hungarian immunologists Hungarian physiologists Members of the Hungarian Academy of Sciences 1979 deaths 1915 births