Lethal Concentration
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Lethality (also called deadliness or perniciousness) is how capable something is of causing
death Death is the end of life; the irreversible cessation of all biological functions that sustain a living organism. Death eventually and inevitably occurs in all organisms. The remains of a former organism normally begin to decompose sh ...
. Most often it is used when referring to
diseases A disease is a particular abnormal condition that adversely affects the structure or function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical conditions that are asso ...
,
chemical weapons A chemical weapon (CW) is a specialized munition that uses chemicals formulated to inflict death or harm on humans. According to the Organisation for the Prohibition of Chemical Weapons (OPCW), this can be any chemical compound intended as ...
,
biological weapons Biological agents, also known as biological weapons or bioweapons, are pathogens used as weapons. In addition to these living or replicating pathogens, toxins and biotoxins are also included among the bio-agents. More than 1,200 different kin ...
, or their
toxic Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a subst ...
chemical components. The use of this term denotes the ability of these weapons to kill, but also the possibility that they may not kill. Reasons for the lethality of a weapon to be inconsistent, or expressed by percentage, can be as varied as minimized exposure to the weapon, previous exposure to the weapon minimizing susceptibility, degradation of the weapon over time and/or distance, and incorrect deployment of a multi-component weapon. This term can also refer to the after-effects of weapon use, such as
nuclear fallout Nuclear fallout is residual radioactive material that is created by the reactions producing a nuclear explosion. It is initially present in the mushroom cloud, radioactive cloud created by the explosion, and "falls out" of the cloud as it is ...
, which has highest lethality nearest the deployment site, and in proportion to the subject's size and nature; e.g. a child or small animal. Lethality can also refer to the after-effects of a major chemical or oil/gas process loss of containment, causing fire, explosion, or a toxic cloud. Lethality curves can be developed in
process safety Process safety is an interdisciplinary engineering domain focusing on the study, prevention, and management of large-scale fires, explosions and chemical accidents (such as toxic gas clouds) in process plants or other facilities dealing with haza ...
to assess and describe mortality patterns around the accident location. The impact is typically greatest closest to the event site and lessens to the outskirts of the impact zone. Blast overpressure,
thermal radiation Thermal radiation is electromagnetic radiation emitted by the thermal motion of particles in matter. All matter with a temperature greater than absolute zero emits thermal radiation. The emission of energy arises from a combination of electro ...
,
toxicity Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacteria, bacterium, or plant, as well as the effect o ...
and location affect the degree of lethality. Lethality is also a term used by
microbiologist A microbiologist (from Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of microscopic organisms such as bacteria, algae, fungi, and some types of par ...
s and
food scientist Food science (or bromatology) is the basic science and applied science of food; its scope starts at overlap with agricultural science and nutritional science and leads through the scientific aspects of food safety and food processing, informing ...
s as a measure of the ability of a process to destroy bacteria.Stumbo, C.R. ''Thermobacteriology in Food Processing''. Elsevier, 2013. 145. Lethality may be determined by enumeration of survivors after incremental exposures.


See also

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Lethal dose In toxicology, the lethal dose (LD) is an indication of the lethal toxicity of a given substance or type of radiation. Because resistance varies from one individual to another, the "lethal dose" represents a dose (usually recorded as dose per kilog ...
, an indication of the lethal toxicity of a given substance or type of radiation *
Stopping power Stopping power is the supposed ability of a weapon – typically a ranged weapon such as a firearm – to cause a target (human or animal) to be incapacitated or immobilized. Stopping power contrasts with lethality in that it pertains only to a ...
*
Toxicity Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacteria, bacterium, or plant, as well as the effect o ...


References

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