Ladin's sign is a
clinical sign
Signs and symptoms are the observed or detectable signs, and experienced symptoms of an illness, injury, or condition. A sign for example may be a higher or lower temperature than normal, raised or lowered blood pressure or an abnormality showin ...
of
pregnancy
Pregnancy is the time during which one or more offspring develops ( gestates) inside a woman's uterus (womb). A multiple pregnancy involves more than one offspring, such as with twins.
Pregnancy usually occurs by sexual intercourse, but ...
in which there is softening in the midline of the
uterus
The uterus (from Latin ''uterus'', plural ''uteri'') or womb () is the organ in the reproductive system of most female mammals, including humans that accommodates the embryonic and fetal development of one or more embryos until birth. The ...
anteriorly at the junction of the uterus and
cervix
The cervix or cervix uteri (Latin, 'neck of the uterus') is the lower part of the uterus (womb) in the human female reproductive system. The cervix is usually 2 to 3 cm long (~1 inch) and roughly cylindrical in shape, which changes durin ...
. It occurs and is detectable with a manual examination at about 6 weeks' gestation. Ladin's sign is often present during the woman's first pelvic exam when pregnancy is suspected. Cervical length is also significant in pregnancy and shorter or shortening length can increase chances of preterm labour and delivery as this shortening happens naturally at the beginning of labour. The cervix softens from conception and combined with other signs of early pregnancy, detecting Ladin's sign can assist clinicians in verifying a diagnosis of pregnancy.
Abnormal softening of the cervix can also occur in pregnancy, so testing for abnormalities of uterine cervical softening, including sheer wave speed measurement, can be used as a method of distinguishing between normal and abnormal softening.
See also
*
Chadwick sign Chadwick sign is a bluish discoloration of the cervix, vagina, and labia resulting from increased blood flow. It can be observed as early as 6 to 8 weeks after conception, and its presence is an early sign of pregnancy.
These colour changes were d ...
*
Goodell's sign In medicine, Goodell's sign is an indication of pregnancy. It is a significant softening of the vaginal portion of the cervix from increased vascularization. This vascularization is a result of hypertrophy and engorgement of the vessels below the gr ...
*
Hegar sign Hegar's sign is a non-sensitive indication of pregnancy in women—its absence does not exclude pregnancy. It pertains to the features of the cervix and the uterine isthmus. It is demonstrated as a softening in the consistency of the uterus, and the ...
References
{{Eponymous medical signs for urinary system, reproductive system, and obstetrics
Medical signs
Obstetrics
Midwifery