Ligand-dependent corepressor is a
protein that in humans is encoded by the ''LCOR''
gene.
Function
LCOR is a transcriptional
corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound
nuclear receptor
In the field of molecular biology, nuclear receptors are a class of proteins responsible for sensing steroids, thyroid hormones, vitamins, and certain other molecules. These receptors work with other proteins to regulate the expression of speci ...
s through a single LxxLL motif, also referred to as a nuclear receptor (NR) box.
References
Further reading
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External links
PDBe-KBprovides an overview of all the structure information available in the PDB for Human Ligand-dependent corepressor
Transcription coregulators
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