Karl Hürthle (March 16, 1860 – March 23, 1945) was a German

physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical a ...

and histologist who was a native of

Ludwigsburg Ludwigsburg (; Swabian: ''Ludisburg'') is a city in Baden-Württemberg, Germany, about north of Stuttgart city centre, near the river Neckar. It is the largest and primary city of the Ludwigsburg district with about 88,000 inhabitants. It is ...

. In 1884 he received his doctorate from the

University of Tübingen The University of Tübingen, officially the Eberhard Karl University of Tübingen (german: Eberhard Karls Universität Tübingen; la, Universitas Eberhardina Carolina), is a public research university located in the city of Tübingen, Baden-Wü ...

, where he remained until 1886, working as a prosector at the anatomical institute. At Tübingen, he was a student and assistant to physiologists

Karl von Vierordt Karl von Vierordt (July 1, 1818 – November 22, 1884) was a German physiologist. Vierordt was born in Lahr, Baden. He studied at the universities of Berlin, Göttingen, Vienna, and Heidelberg, and began a practice in Karlsruhe in 1842. In ...

(1818-1884) and Paul Grützner (1847-1919). In 1887 he became an assistant to

Rudolf Heidenhain Rudolf Peter Heinrich Heidenhain (; 29 January 1834 – 13 October 1897) was a German physiologist born in Marienwerder, East Prussia (now Kwidzyn, Poland). His son, Martin Heidenhain, was a highly regarded anatomist. Academic career He studie ...

(1834-1897) at the physiological institute in Breslau, and in 1895 attained the title of ''professor extraordinarius''. In 1898, he succeeded Heidenhain at the department of physiology in Breslau. Later in his career, he worked at the physiological institute at Tübingen, and also in the department of experimental

pathology Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...

and

therapy A therapy or medical treatment (often abbreviated tx, Tx, or Tx) is the attempted remediation of a health problem, usually following a medical diagnosis. As a rule, each therapy has indications and contraindications. There are many different ...

at the Kerckhoff Institute in Bad Nauheim (now known as the

Max Planck Institute Max or MAX may refer to: Animals * Max (dog) (1983–2013), at one time purported to be the world's oldest living dog * Max (English Springer Spaniel), the first pet dog to win the PDSA Order of Merit (animal equivalent of OBE) * Max (gorilla) (1 ...

for Heart and Lung Research). Hürthle is remembered for contributions made in the field of

haemodynamics Hemodynamics or haemodynamics are the dynamics of blood flow. The circulatory system is controlled by homeostatic mechanisms of autoregulation, just as hydraulic circuits are controlled by control systems. The hemodynamic response continuously m ...

. He performed extensive research involving

blood pressure Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" r ...

, blood viscosity, intracranial circulation, blood supply of organs, vasodilatation, and a phenomenon he called ''Windkesseleffekt'', of which he demonstrated plays an important role in the maintenance of blood pressure. He also described the motion phenomena of the arterial vascular wall, performed studies involving the structure of striated muscle, and investigated the function and

morphology Morphology, from the Greek and meaning "study of shape", may refer to: Disciplines *Morphology (archaeology), study of the shapes or forms of artifacts *Morphology (astronomy), study of the shape of astronomical objects such as nebulae, galaxies, ...

of the

thyroid gland The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans it is in the neck and consists of two connected lobe (anatomy), lobes. The lower two thirds of the lobes are connected by a thin band of Connective tissue, tissue cal ...

. A large, granular

epithelial Epithelium or epithelial tissue is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. It is a thin, continuous, protective layer of compactly packed cells with a little intercellula ...

cell sometimes found in the thyroid is called a "

Hürthle cell A Hürthle cell is a cell in the thyroid that is often associated with Hashimoto's thyroiditis as well as benign and malignant tumors ( Hürthle cell adenoma and Hürthle cell carcinoma, formerly considered a subtype of follicular thyroid cancer). ...

".Hürthle cells
@ Who Named It

Selected publications

* ''Zur Technik der Untersuchung des Blutdruckes'' (Studies involving blood pressure), 1888 * ''Untersuchungen über die Innervation der Hirngefäße'' (Studies on the innervation of brain vessels), 1889 * ''Ueber eine Methode zur Registrierung des arteriellen Blutdrucks beim Menschen'' (A method for registration of arterial blood pressure in humans), 1896 * ''Über die Struktur der querstreiftem Muskelfasern von Hydrophilus'' 1909 * ''Histologische Struktur und optische Eigenschaften der Muskeln'' (Histological structure and optical properties of muscles), 1925 * ''Blutkreislauf im Gehirn'' (Blood circulation in the brain), 1927 * ''Die mittlere Blutversorgung der einzelnen Organe'' (The average blood supply to the individual organs), 1927 * ''Über tonische und pulsatorische Bewegungen der Arterienwand'' (About tonic and pulsatory movements of the arterial wall), 1939

References

* ''This article was based on a translation of an equivalent article at the

German Wikipedia The German Wikipedia (german: Deutschsprachige Wikipedia) is the German-language edition of Wikipedia, a free and publicly editable online encyclopedia. Founded on March 16, 2001, it is the second-oldest Wikipedia (after the English Wikipedia), ...

External links

* {{DEFAULTSORT:Hurthle, Karl German physiologists German histologists 1945 deaths 1860 births Academic staff of the University of Breslau University of Tübingen alumni